People with autism may develop new behaviours in adolescence or early adult life, in addition to those associated with the primary disorder. Some of these behaviours have been postulated to be symptoms of depressive disorder. This article notes the methodological problems of investigating depression in people with autism. The authors also attempt to clarify the symptoms that may be significant in diagnosing depression in this group, by using treatment response methods.
BERNEY, T.P. (2000) ‘Autism: An Evolving Concept’, British Journal of Psychiatry176: 20-25.
2.
CLARKE, D.J. & GOMEZ, G.A. (1999) ‘Modified DCR-10 Criteria in the Diagnosis of Depression Associated with Intellectual Disability’, Journal of Intellectual Disability Research43 (5): 413-420.
3.
CLARKE, D.J. , BAXTER, M., PERRY, D. & PRASHER, V. (1999) ‘The Diagnosis of Affective and Psychotic Disorders in Adults with Autism: Seven Case Reports’, Autism3 (2): 149-164.
4.
CLINICAL PSYCHIATRIC COMMITTEE (1965) ‘Report to the Medical Research Council by its Clinical Psychiatry Committee: Clinical Trial of the Treatment of Depressive Illness’, British Medical Journal881-886.
5.
COOPER, S.A. & COLLACOTT, R.A. (1994) ‘Standardised Diagnostic Criteria for Depression in People with Learning Disabilities’, in Abstracts of the Mental Handicap Section of the Royal College of Psychiatrists Annual Meeting. London: Royal College of Psychiatrists.
6.
COOPER, S.A. & COLLACOTT, R.A. (1996) ‘Depressive Episodes in Adults with Learning Disability’, Irish Journal of Psychological Medicine13 (3): 105-113.
7.
DEPARTMENT OF HEALTH (1995) The Health of the Nation: A Strategy for People with Learning Disability. London: HMSO.
8.
FRASER, W.I. (2000) ‘Three Decades after Penrose’, British Journal of Psychiatry176: 10-11.
9.
GHAZIUDDIN, M. & GREDEN, J. (1998) ‘Depression in Children with Autism/Pervasive Development Disorder: A Case-Control Family History Study’, Journal of Autism and Developmental Disorder28: 111-115.
10.
GHAZIUDDIN, M. & TSAI, L. (1991) ‘Depression in Autistic Disorder’, British Journal of Psychiatry159: 721-723.
11.
GHAZIUDDIN, M. , TSAI, L. & GHAZIUDDIN, N. (1991) ‘Fluoxetine in Autism with Depression’, Journal of the American Academy of Child and Adolescent Psychiatry30: 508-509.
12.
GILLBERG, C. & SCHAUMANN, H. (1989) ‘Autism: Specific Problems of Adolescence’, in Diagnosis and Treatment of Autism. pp. 375-382. New York: Plenum.
13.
GOODMAN, W.K. , PRICE, L.H., RASMUSSEN, S.A., DELGADD, D.L., HENINGER, G.R., CHARNEY, D.S. (1989) ‘Efficiency of Fluovoxamine in Obsessive Compulsive Disorder: A Double-Blind Comparison with Placebo’, Archives of General Psychiatry46: 36-44.
14.
HELLINGS, J.A. , KELLY, L.A., GABRIELLI, W.F., KILGORE, E. & SHAH, P. (1996) ‘Sertraline Response in Adults with Mental Retardation and Autistic Disorder’, Journal of Clinical Psychiatry57 (8): 333-336.
15.
HOLMES, N. , SHAH, A. & WING, L. (1982) ‘The Disability Assessment Schedule: A Brief Screening Device for Use with the Mentally Retarded’, Psychological Medicine12: 879-890.
16.
HUMBLE, M. & WISTEDT, B. (1992) ‘Serotonin Panic Disorder and Agoraphobia: Short-Term and Long-Term Efficacy of Citalopram in Panic Disorders’, International Clinical Psychopharmacology6 (suppl. 5): 21-39.
17.
LAINHART, J.E. & FOLSTEIN, S.E. (1994) ‘Affective Disorders in People with Autism: A Review of Published Cases’, Journal of Autism and Developmental Disorders24: 587-601.
18.
LOWRY, M.A. & SOVNER, R. (1992) ‘Severe Behaviour Problems Associated with Rapid Cycling Bipolar Disorder in Two Adults with Profound Mental Retardation’, Journal of Intellectual Disability Research36 (3): 296-281.
19.
MARSTON, G.M. , PERRY, D.W. & ROY, A. (1997) ‘Manifestations of Depression in People with Intellectual Disability’, Journal of Intellectual Disability Research41 (6): 476-480.
20.
MEINS, W. (1995) ‘Symptoms of Major Depression in Mentally Retarded Adults’, Journal of Intellectual Disability Research39: 41-45.
21.
MEINS, W. (1996) ‘A New Depression Scale Designed for Use with Adults with Mental Retardation’, Journal of Intellectual Disability Research40: 222-226.
22.
PERRY, D.W. , HINDER, S., KRISHNAN, V.H.R. & ROY, A. (1996) ‘The Use of Specific Serotonin Re-Uptake Inhibitors in People with Learning Disability, Autism and Depression’, Human Psychopharmacology11: 425-426.
23.
REISS, S. & ROJAHN, J. (1993) ‘Joint Occurrence of Depression and Aggression in Children and Adults with Mental Retardation’, Journal of Intellectual Disability Research37: 287-294.
24.
RICKETTS, R.W. , GOZA, A.B., ELLIS, C.R., SINGH, Y.N., SINGH, N.N. & COOKE, J.C. (1993) ‘Fluoxetine Treatment of Severe Self-Injury in Young Adults with Mental Retardation’, Journal of the American Academy of Child and Adolescent Psychiatry32: 865-870.
25.
SOVNER, R. , FOX, C.J., LOWRY, M.J. & LOWRY M.A. (1993) ‘Fluoxetine Treatment of Depression and Associated Self Injury in Two Adults with Mental Retardation’, Journal of Intellectual Disability Research37: 301-311.
26.
SPREATS, S. , BEHAR, D., RENESKI, B. & MIAZZO, P. (1989) ‘Lithium Carbonate for Aggression in Mentally Retarded Persons’, Comprehensive Psychiatry30: 505-511.
27.
WORLD HEALTH ORGANIZATION (1992) The International Classification of Mental and Behavioural Disorders: Clinical Descriptions and Diagnostic Guidelines, 10th rev. (ICD-10). Geneva: WHO.