This study aimed to examine the relationship between psychological well-being, spiritual well-being, and health-related quality of life (HRQOL) among patients with coronary artery disease. A descriptive correlational design and a convenience sampling method were adopted and data were collected from 401 patients suffering from coronary artery disease who were treated in outpatient clinics in government, private, and educational health sectors from June 2022 to September 2022. Findings demonstrated that participants reported low and moderate levels of psychological and spiritual well-being, and high HRQOL. A significant positive correlation was demonstrated between HRQOL and income, educational level, psychological well-being, and spiritual well-being. Income, psychological well-being, and spiritual well-being were the main predictors for HRQOL. Thus, this study could help policymakers, hospital administrators, and healthcare professionals develop proper strategies and programs to promote psychological and spiritual well-being, which influence patients’ treatment outcomes and increase their HRQOL.
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