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Abstract

Background: Many children and young people (CYP) presenting with mental health crises are admitted to hospital due to concerns around illness severity and risk. Whilst inpatient admissions have an important role for such children, there are a number of burdens associated with them, and safe avoidance of admissions is favourable. We systematically reviewed the literature for studies of interventions reported as alternatives to a hospital admission in CYP presenting with mental health crises, in any inpatient setting. Methods: Three databases (PsychInfo, PubMed and Web of Science) were searched for peer-reviewed papers in October 2020, with an updated search in May 2021. Results: We identified 19 papers of interventions delivered in the emergency department, the home, outside of home but outside of clinics and in hospital clinics. The quality of most included studies was low, with less than half being randomised controlled trials and only half of these at low risk of bias. The best quality studies and greatest evidence for efficacy came from in-home interventions, in particular multisystemic therapy, which improved psychological outcomes, and though a large number of CYP still ended up being admitted, there appeared to be decreased length of stay. Conclusions: Overall, we could not recommend a particular intervention as an alternative to inpatient admission; however, our review describes benefits across a range of types of interventions that might be considered in multi-modal treatments. We also provide recommendations for future research, in particular the evaluation of new interventions as they emerge.

Keywords

Child adolescent mental health inpatient admissions crisis

Background

Mental health disorders are a substantial burden for children and young people’s (CYP) health globally (Polanczyk et al., 2015), with suicide a leading cause of death (Wasserman et al., 2005). In the UK, recent data have shown that 16% of CYP have a mental health disorder, with over half of older adolescents with a disorder having self-harmed or attempted suicide (Vizard et al., 2020). Similar prevalence rates have been reported in Europe and the United States (Kovess-Masfety et al., 2016; Merikangas et al., 2010). Though these are longstanding issues, the recent COVID-19 pandemic appears to have worsened the mental health for some children (Ford et al., 2021). Many CYP with mental health disorders will present to health care providers with an acute (sometimes called psychiatric) crisis due to their mental health. Such crises can be defined as subjective experiences where a change in mental wellbeing occurs, and the person becomes unstable or at risk to themselves or others (Jennings & Child, 2017). In high income countries, numbers of such presentations for CYP seemed to have increased, both to secondary and primary care (Mahajan et al., 2009; Morgan et al., 2017; Newton et al., 2009; Pittsenbarger & Mannix, 2014). Severity of illness, concern about risk (especially in relation to suicide) (Hawton et al., 2012), available community services (Lancet, 2020) and social circumstances (Paranjothy et al., 2018) may mean that such presentations result in an inpatient admission. Whilst hospitalisation rates for most paediatric conditions in high income countries have decreased in recent years, admissions because of mental health have increased (Torio et al., 2015).

Inpatient mental health admissions can provide important and vital services for significantly unwell CYP (Green et al., 2007), for example more intensive levels of care and the opportunity for longer, good quality, therapeutic relationships with inpatient staff (Sergent, 2009). However, they can also carry substantial burden. Mental health admissions can be lengthy, in locations away from a usual place of residence, leading to disconnection from friends and family and separation from education or employment. These burdens are especially amplified for CYP experiencing repeated admissions (Miller et al., 2020). Inpatient mental health admissions are also more costly for health care systems (Green et al., 2007) versus outpatient care. Demand can also outstrip capacity (O’Herlihy et al., 2003), resulting in admissions of CYP in adult psychiatric wards or non-mental health inpatient settings such as paediatric medical wards (Worrall et al., 2004). Safe and effective interventions acting as alternatives to inpatient admissions for CYP presenting in crisis are therefore highly favourable. Policy makers have turned attention on to this issue, for example in the UK there are strategies in place to improve community services (Alderwick & Dixon, 2019).

Developing and implementing alternatives to inpatient mental health admissions for CYP presenting in crisis requires an up-to-date synthesis of the literature. Previous systematic reviews on this topic (Kwok et al., 2016; Shepperd et al., 2009) are now outdated (with the latest literature search performed in 2014) and also included papers of interventions with an admission component (such as short-term hospitalisations) which could be a confounder for the effects of proposed alternatives. We therefore systematically reviewed the literature for studies of interventions reported as alternatives to a mental health admission in CYP presenting with a significant mental health crisis, in any inpatient setting. We specifically examined for:

effectiveness at avoiding admission or any impact on reducing the length of an inpatient stay if one followed.

Improvements in psychological parameters for CYP secondary to such interventions.

Methods

We searched three databases: PsychInfo, PubMed and Web of Science in October 2020, with an updated search in May 2021. We used search terms to encompass ‘children and young people’, ‘mental health crisis’ and ‘potential locations of care’ (Supplementary Appendix A). Searches were conducted individually by two researchers (DC and IL) who selected abstracts for inclusion or exclusion. Papers were then downloaded and considered independently, with LH providing adjudication. Reference lists within studies were also screened.

We included studies reporting outcomes of interventions specifically as alternatives to a mental health admission for CYP presenting with a mental health crisis. We defined admission as any hospitalisation in any inpatient setting (including general medical settings). We excluded (1) studies where some or all participants were >18 years; (2) studies not published in English; (3) reviews; (4) papers which did not provide any outcome measures or insufficient outcome measures, or only described interventions; (4) studies where the intervention included an admission.

Independent bias assessments were conducted by DC and IL using the Cochrane Review tools for assessing risk of bias in randomised trials (RCTs) (Sterne et al., 2019) and non-RCT (Sterne et al., 2016). Discrepancies were discussed for agreement with final adjudication by LH.

Results

We found 782 papers in initial searches of databases and were left with 640 unique studies after duplicate removal. Seventy-one papers were retrieved, with 60 excluded based on full text assessment. We found an additional 8 studies from screening reference lists. We included a total of 19 studies. A summary of the search with numbers is shown in Figure 1.

Figure 1.

PRISMA flow diagram of included and excluded studies.

Eight studies were RCTs, 4 studies were service evaluations, 4 studies used an uncontrolled pre–post-treatment investigation, 2 papers used pre-intervention historical/retrospective control groups and 1 paper used a matched control group. Fourteen studies were conducted in the USA, 2 were conducted in Germany, 2 in Canada and 1 in the UK. Two studies reported on interventions specifically for CYP with suicidal risk, 1 for psychosis and 1 for disruptive behaviour/externalising crisis presentations and 15 were for mixed types of crisis mental health presentations. For RCTs, we found 4 papers at low risk of bias, 2 raising some concerns and 2 at high risk of bias, and for non-RCTs, we found 1 paper at low risk of bias, 2 papers at moderate risk, 6 papers at serious risk of bias and 2 papers at critical risk. Detailed summaries of included studies, including bias assessment are shown in Table 1. Detailed rationale for classifying final bias category for each study is shown in Supplementary Appendix B.

Table 1.

Summary of the studies included.

Author (year), country	Design	Sample	N (%male, %female)	Age range (mean, SD)	Outcome measure(s)	Intervention (duration)	Intervention details	Comparison condition	Main findings	Conclusions	Overall risk of bias
Single-session interventions for emergency department crisis presentations
Gillig (2004), USA	Service evaluation	Adolescents admitted for emergency hospitalisation evaluation	48 (45.83%, 54.17%)	12–18 (modal age: 16.5)	Inpatient admission rate	Emergency evaluation interview + brief therapeutic intervention (max. 24 hours)	Semi-structured interview and mental status evaluation. After that, a supportive, reality-based, present-focused therapeutic intervention was offered. Adolescents could be helped for up to 24 hours if necessary	N/A	5 patients were hospitalised right after the evaluation (10%). 0 patients were hospitalised in the following month. 4.2% (n = 2) patients were hospitalised within 6 months	The majority of the adolescents referred to emergency hospitalisation were maintained in the community after receiving the emergency evaluation and brief therapeutic intervention	Critical
Parker et al. (2003), Canada	Service Evaluation	Adolescents with psychiatric crisis	n.s.	n.s.	Admission rate and length of inpatient stay	Rapid response model (single-session offered max 48 hours post-referral)	Brief interview focused on crisis and risk	Pre-implementation	Site 1: RRM phase had no significant impact on number of consultations leading to admission. RRM phase had a significant effect on the monthly average length of inpatient stay (F(1,42) = 3.1, p < .05): M₁ = 14.8, M_{first RRM} = 11.2, M_{RRM termination} = 9.5, M_{second RRM} = 19.3. Site 2: Significant effects of RRM phase on number of consultations leading to admission: decrease from 22% pre-RRM to 2% post-RRM (χ² = 31.6, N = 340, d.f. = 1, p < .001). Effect of RRM phase on length of inpatient stay not investigated	Suggestion of lower admission rate and length of stay associated with RRM implementation, although each was true or investigated only for one site rather than both	Serious
Wharff et al. (2012) USA	Cohort external historical retrospective control group	Suicidal adolescents at the ED	In experimental condition: 100 (24%, 76%)	13–18 (15.6, 1.5)	Admission rate	Family-based crisis intervention (FBCI) in the emergency room (single-session)	CBT- and family-based session using psychoeducation, therapeutic readiness and safety planning	Suicidal adolescents (n = 150) at ED before the implementation of the intervention	Significant decrease in admission rate from pre-FBCI (55%) to post-FBCI (35%): p < .0001	FBCI was associated with a lower percentage of patients admitted to hospital in comparison to a control group attending the clinic before its implementation	Low
Exclusively in-home interventions
Henggeler et al. (1999), USA	RCT	Adolescents referred to emergency psychiatric hospitalisation	113 (65%, 35%)	10–17 (13, n.s.)	GSI-BSI, CBCL, PEI, self-esteem subscale of FFS	Multisystemic therapy (3–6 months)	Family and behavioural therapy strategies used to intervene in the key social systems	Hospitalisation (n = 56)	Both groups reported pre- to post-treatment improvements in GSI-BSI (child and caregiver-reported), CBCL internalising (caregiver-reported) and CBCL-social functioning (caregiver-reported), and a deterioration in FACES-III family adaptability (caregiver) (p < .05). MST was reported to be superior to hospitalisation in improving externalising symptoms in both caregiver and teacher-reports: F(1,102) = 6.55, p < .011 and F(1, 45) = 4.10, p < .048. MST patients reported a pre- to post-treatment decrease from M = 73.3 (SD = 10.3) to M = 63.7 (SD = 12.4) in caregiver reports and M= 71.1 (SD = 10.7) to M = 64.8 (SD = 11.8) in teacher-reports. Hospitalised patients reported a pre–post-treatment decrease from M = 70.6 (SD = 12.3 to M = 64.3 (SD = 14.2) in caregiver reports and an increase from M = 67.8 (SD = 15.1) to M = 68.0 (SD = 13.0) in teacher-reports. MST was also reported to be superior than hospitalisation in FACES-III family adaptability (youth-reported) and Faces-III family cohesion (caregiver-reported): F(2, 220) = 3.28, p = .039 and F(2, 206) = 6.56, p < .001. Families in the MST condition became more structured M = 23.1 (SD = 6.7) to M = 21.8 (SD = 8.1) in comparison to admitted patients: M = 22.1 (SD = 6.7) to M = 23.8 (SD = 7.4). In the MST, family cohesion increased from pre- to post-treatment from M = 32.2 (SD = 8.4) to M = 34.4 (SD = 6.6) while this decreased in the hospitalisation condition from M = 36.1 (SD = 5.3) to M = 34.7 (SD = 6.4). Patients in the MST condition spent less day out of school (FFS) by the end of treatment (M = 14 SD = 36.8) than hospitalised patients (M = 37 SD = 59.8): F(1,110) = 5.72, p < .001. Hospitalisation was reported to be superior to MST in increasing youth self-esteem (FFS): F(1, 109) = 7.72, p = .006. Hospitalised patients increased their pre- post-treatment score from M = 2.21 (SD = 1.0) to M = 2.73 (SD = 0.9) while patients in the MST condition decreased their pre- post-treatment score from M = 2.57 (SD = 0.9) to M = 2.55 (SD = 1.1). No significant time- or group-differences were reported for PEI alcohol, marijuana and arrests, Faces-III family cohesion (youth-reported), CBCL-social functioning (youth-reported), FFS conventional involvement and FFS Antisocial friend (p > .05)	While both treatments improved child’s self-reported and caregiver-reported symptoms severity, caregiver-reported internalising symptoms and social functioning and family adaptability as reported by youths, MST proved to be superior to hospitalisation in many areas. For example, MST was better than hospitalisation at improving externalising symptoms (caregiver and teacher-reports), family adaptability (youth-reported) and cohesion (caregiver-reported) and was associated with less days spent out of school. Hospitalisation was however superior to MST in improving youth self-esteem	Low
Henggeler et al. (2003), USA	RCT	Adolescents referred to emergency psychiatric hospitalisation	113 (65%, 35%)	10–17 (12.9, 2.1)	GSI-BSI, CBCL, PEI, self-esteem subscale of FFS	Multisystemic therapy (3–6 months)	Family and behavioural therapy strategies used to intervene in the key social systems	Hospitalisation (n = 56)	Clinical improvements were maintained until the 12-months follow-up point, but the group differences which were initially found in Henggeler et al. (1999) and Huey et al. (2004) dissipated	Both MST and hospitalisation were effective at improving the of CYP in crises on the long-term, but initial differences seen between groups dissipated at 1-year post-treatment	Low
Huey et al. (2004), USA	RCT	Adolescents referred to emergency psychiatric hospitalisation	113 (65%, 35%)	10–17 (12.9, 2.1)	FFS, BSI, CBCL, HSC, YRBSS	Multisystemic therapy (3–6 months)	Family and behavioural therapy strategies used to intervene in the key social systems	Hospitalisation (n = 56)	A significant time effect was found in both groups for most measures, with patients scoring lower at follow-up than pre-treatment in CBCL caregiver-rated attempted suicide (t = −5.25, p < .001), CBCL anxiety/depression (t = −5.70, p < .001), and youth-rated BSI suicidal ideation (t = −5.97, p < .001), BSI depression (t = −3.47, p < .001) and hopelessness (t = −2.65, p < .01). Group differences for these measures were not significant. Patients in the MST condition reported a steeper decrease in child- reported suicide attempts from pre-treatment (31%) to follow-up (4%) than hospitalised CYP (from 19% to 4%): t = 3.60, p <.001. This effect was not reported for the caregiver-rated attempted suicide where results did not reach statistical significance (p > .05). Different trajectories were reported in the two groups for FFS caregiver-rated parental control (t = 2.08, p < .05), with MST parents reporting an initial increase in control at post-treatment (M = 3.06, SD = 0.54) in comparison to pre-treatment (M = 2.85, SD = 0.58, but which then decreased back to baseline levels at 1-year follow-up (M = 2.87, SD = 0.59). In the hospitalisation group, parental control was maintained at similar levels from pre-treatment (M = 2.92, SD = 0.62) to post-treatment (M = 2.95, SD = 0.51) and follow-up (M = 2.92, SD = 0.54). No significant time or group effects were reported for the youth-rated FFS parental control	Compared to hospitalisation, MST was found to be more effective in reducing youth-reported suicide attempts. Both treatments were equally effective in decreasing caregiver-reported attempted suicide, suicidal ideation, hopelessness and depression and anxiety symptoms	Low
Lay et al. (2001), Germany	Uncontrolled pre-post study	CYP with externalising psychiatric disorders requiring inpatient admission	50 (74%, 26%)	5–16 (9.8, 2.4)	SGKJ, MEI, non-involved clinician in the care of the child ratings on: symptom load, level of functioning, psychosocial environment	Home-treatment (1–2/week for 2 hours for 3.5 months)	Utilised principles of behaviour modification and parent training: reinforcement schedules, training of social skills and therapeutic exercises	N/A	A significant decrease was reported in the MEI total symptoms score from pre-treatment (M = 11.9) to post-treatment (M = 8.1): p < .001. Before treatment, n = 18 (36%) of the sample scored ≤9, n = 27 (54%) scored 10–19 and n = 5 (10%) scored ≥20 in the MEI. After treatment, n = 34 (68%) scored ≤9, n = 14 (28%) scored 10–19 and n = 2 (4%) scored ≥20. This difference between pre- and post-treatment reached statistical significance (p < .001). Significant pre- to post-treatment differences were reported in the child-rated psychosocial functioning as well (p < .001), with n = 27 (54%) and n = 23 (46%) scoring 5 and 4 respectively, while post-treatment n = 2 (4%) scored 4, n = 20 (40%) scored 5, n = 17 (34%) scored 6, n = 9 (18%) scored 7, n = 1 (2%) scored 8 and n = 1 (2%) scored 9. In comparison to pre-treatment, significantly more participants achieved higher scores in parent-rated psychosocial functioning at post-treatment in the following sub-domains: family (p = .001), peers (p = .02), interests (p = .001) and autonomy (p = .02), while school performance did not reach statistical significance (p = .22) and school discipline and social behaviour had no data. In comparison to pre-treatment, significantly more participants achieved higher scores in all the therapist-rated sub-domains: family (p = .001), peers (p = .002), interests (p = .001), autonomy (p = .001), school performance (p = .004), school discipline (p = .002) and school social behaviour (p = .003)	The home-treatment was associated with a decrease in psychological symptoms and psychosocial adjustment, showing positive results in almost all areas of functioning considered	Serious
Mosier et al. (2001), USA	Uncontrolled pre-post study	CYP who require restrictive and intensive mental health services	104 (62%, 38%)	4–17 (n.s.)	Y-OQ	In-home family centered treatment	24/7 access to services, exploring areas to improve as a family system	N/A	Scores on the Y-OQ decreased from pre-treatment through the intervention: pre-treatment M = 106.53 SD = 36.68), time 2 (M = 90.30 SD = 37.26), time 3 (M = 79.48 SD = 40.52), post-treatment (M = 75.17 SD = 37.79). At time 2 (approximately 2 weeks post-referral), out of the 64 people who provided data, 5 recovered (8%), 29 achieved reliable improvements (45%), 30 remained unchanged (47%) and 0 deteriorated (0%). At time 3 (approximately 2 weeks post time 2), out of the 46 people who provided data, 10 patients recovered (22%), 18 reliably improved (39%), 8 remained unchanged (17%) and 10 deteriorated (22%). At time 4 (end of treatment), out of the 29 people who provided data, 5 patients recovered (17%), 13 patients improved reliably (45%), 5 patients remained unchanged (17%) and 6 patients deteriorated (21%). Comparing the mean Y-OQ score at the end of treatment of the in-home family treatment to the normative scores of a sample receiving inpatient/outpatient treatment revealed that although the mean was lower for the in-home intervention (M = 75.17 SD = 37.79) than for the control (M = 78.6 SD = 36.40), this difference did not reach statistical significance (t(369) = 1.17, p > .05)	The in-home family treatment was suggested to lead to improvements or even recovery for a number of patients, from pre-treatment to throughout the treatment and finalisation. When compared to a group of patients receiving outpatient treatment, no evidence was found for superiority of the in-home intervention	Serious
Rowland et al. (2005), USA	RCT	CYP at risk of out-of-home placement	31 (58%, 42%)	n.s. (14.5, n.s.)	Out-of-home placement (including admission), CBCL, YRBSS, PEI, criminal activity, SRD, school placement, FACES-III, SSQ	Multisystemic therapy (3–6 months)	Family and behavioural therapy strategies used to intervene in the key social systems	Usual care	A significantly higher change was reported in externalising symptoms for MST in comparison to usual care (F(1, 25) = 4.62, p = .041), with MST children reporting a decrease in scores from M = 66.80 (SD = 12.74) at pre-treatment to M = 60.53 (SD = 13.58) at follow-up and children in usual care reporting similar scores between pre-treatment (M = 63.36, SD = 10.93) and follow-up (M = 63.00, SD = 11.39). A significantly higher change was reported in internalising symptoms for MST in comparison to usual care (F(1,28) = 6.05, p =.021), with MST children reporting a decrease in scores from M = 62.27 (SD = 9.79) at pre-treatment to M = 57.07 (SD = 13.19) at follow-up and children in usual care reporting an increase in scores from pre-treatment (M = 57.29, SD = 14.42) to follow-up (M = 59.00, SD = 11.80). MST was also superior in decreasing minor delinquencies in comparison to usual care (F(1, 25) = 5.74, p = .02), with MST patients reporting a steeper decrease in scores from M = 26.33 (SD = 26.44) at pre-treatment to M = 5.27 (SD = 8.25) at follow-up, than usual care patients (pre-treatment: M = 5.53 SD = 10.88; follow-up M = 3.13, SD = 5.26). By the end of the trial, youth in the MST condition spent 42% more days per month in general education settings (M = 85.64, SD = 78.91) compared to youth in the usual care condition (M = 49.64, SD = 77.25): F(1, 24) = 3.16, p = .07. By the end of the trial, MST patients spent significantly less monthly days in out-of-home placement (M = 3.75 SD = 4.77) than youth in the usual care condition (M = 11.83 SD = 11.46): F(1, 26) = 5.68, p = .025. No significant group or time differences were found for youth dangerousness, caregiver-reported internalising and externalising symptoms, substance abuse, self-reported index offences, arrests/month in the community, family adaptability and cohesion	MST was reported to be superior to usual care in improving youth-rated externalising and internalising symptoms, self-reported minor delinquencies, days spent in general education and monthly days in out-of-home placement by the end of treatment	Some concerns
Schoenwald et al. (2000), USA	RCT	Adolescents referred to emergency psychiatric hospitalisation	113 (65%, 35%)	10–17 (13, n.s.)	Admission rate and length of stay	Multisystemic therapy (3–6 months)	Family and behavioural therapy strategies used to intervene in the key social systems	Hospitalisation (n = 56)	44% of the patients receiving MST were admitted to hospital by the end of treatment. The mean days hospitalised was significantly lower for patients in the MST group (M = 2.39, SD = 4.55) than patients in the control group (M = 8.82, SD = 11.55): t = 3.91, p = .001. The mean hospitalisation days per hospitalised youth was lower in the MST condition (M = 5.44, SD = 5.58) than the control group (M = 8.82, SD = 11.55), but this did not reach statistical significance: p > .50. Patients admitted from MST group spent less days hospitalised per episode (M = 3.78, SD = 5.04) than patients in the control condition (M = 6.06, SD = 4.05), but this difference did not reach statistical significance (p > .50)	The majority of patients receiving MST avoided admission by the end of treatment. It was suggested that MST was superior at decreasing the number of overall days hospitalised and days hospitalised per episode in comparison to admission	Low
Schmidt et al. (2006), Germany	Matched sample control group	CYP requiring psychiatric hospitalisation	105 (n.s.)	6–17 (n.s.)	MEI, behaviour changes (child, parents, therapist)	Home-treatment (3 months)	Child-centred tailored, home-based and family-focused treatment	Hospitalisation	Both groups achieved significant positive pre-treatment to follow-up changes in the total MEI symptom score (p < .001). Hospitalisation was superior in improving the total symptom score and achieving higher behaviour changes. For home-treatment patients, the MEI symptoms scores decreased from M = 12.0 (SD = 5.2) at pre-treatment to M = 8.0 (SD = 5.2) at post-treatment, while for CYP admitted, the scores decreased from M = 14.8 (SD = 5.4) at pre-treatment to M = 6.2 (SD = 3.7) at post-treatment p < .001. Receiving the home-treatment was associated with significant improvements from intake to follow-up in 4 of the 5 functioning subscales (family, peers, interests and autonomy) while for hospitalisation, change from pre-treatment to follow-up was only significant in 3 subscales (family, interests, autonomy). When comparing the degree of change from pre-treatment to follow-up between the two treatment groups, no significant differences were reported for the child- and parent-rated behaviour changes at post-treatment, patients in the home-treatment group scored significantly lower (M = 4.1; SD = 0.9/M = 4.2; SD = 0.7) than patients in the hospitalisation group (M = 4.6; SD = 0.6/M = 4.5; SD = 0.6): child (p = .02), parent (p = .03). These changes were not significant (p = .05) when comparing the therapist ratings for the two treatment groups. When investigating the blind examiners’ rating of each treatment’s effectiveness, hospitalisation proved to be superior in every measure: symptoms (hospitalisation: M = 2.2, SD = 0.9; home: M = 1.8, SD = 1.0; p = .03), level of functioning (hospitalisation: M = 2.0, SD = 0.9; home: M = 1.5, SD = 1.0; p = .01), psychosocial environment (hospitalisation: M = 1.9, SD = 0.9; home: M = 1.3, SD = 1.0; p = .008), global rating (hospitalisation: M = 2.1, SD = 0.9; home: M = 1.6, SD = 1.0; p = .01)	CYP admitted had higher significant improvements reported in the total symptoms score (p < .001) and child- and parent-rated behaviour. Although both treatments led to clinical and social functioning improvements, hospitalisation was superior at improving psychological symptoms and level of functioning and determining positive behaviour changes by the end of treatment	Moderate
Wilmshurst (2002), USA	RCT	CYP with emotional and behavioural disorders (EBDs)	65 (n.s., n.s.)	6–14 (n.s., n.s.)	SCIS, SSRS	Family preservation program (up to 12 hours/week, 12 weeks)	Flexible and intensive in-home support available using problem-solving and CBT-based techniques	5-day residential program (5DR) (5 days/week, 3 months). Individualised and flexible day treatment	A significantly higher decrease in internalising symptoms in the family therapy group was detected from pre- treatment (M = 69.76; SD = 13.3) to 1-year follow (M = 62.58; SD = 11.6) in comparison to the residential treatment where an increase occurred from pre-treatment (M = 65.74; SD = 11.8) to 1 year follow-up (M = 66.41; SD = 12.8): F(2, 62) = 3.92, p = .025. All patients significantly improved in externalising symptoms (F(2, 62) = 28:67, p = 001), behavioural problems (F(2, 66) = 24.89, p = .001) and social competence F (2, 66) = 11.61, p = .001) from pre-treatment to post-treatment and 1 year follow-up, but no significant group differences were reported for these measures (p > .05)	Although both treatments improved externalising and behavioural problems and social competence, the family programme was superior in improving internalising symptoms in comparison to the residential treatment, which was reported to worsen the problems	Some concerns
Outside of the home but outside of hospital clinics
Darwish et al. (2006), UK	Service Evaluation	CYP with complex psychological needs	42 (n.s.)	n.s.	Admission rate	Community intensive therapy (CITT) (n.s.)	Services offered were similar to inpatient setting but delivered in the community. Strong emphasis on interagency network and especially with educational services. Individual and family therapy were offered flexibly, limited group therapy activities, and dieticians, and clinical psychologists were available if needed	A similar sample attending the service before the implementation of the CITT	Number of inpatient admissions decreased considerably after CITT implementation: 5–6 CYP were admitted the year before implementation at any one time while for the 5 years after implementation, 0–1 CYP were admitted every year	CITT was suggested to be effective in reducing the likelihood of inpatient psychiatric admission of CYP with complex mental health needs	Serious
Vanderploeg et al. (2016), USA	Service Evaluation	CYP in psychiatric crisis	n.s.	n.s.	The Ohio scale	Emergency mobile psychiatric services (EMPSs) (average of 20.8 days of help, maximum 45 days)	Emergency crises service delivered at various locations 24/7: crisis stabilisation and support, screening and assessment, suicide assessment and prevention, brief solution-focused interventions, and referral and linkage to ongoing care	N/A	Significant pre- to post-treatment changes occurred in parent- and clinician-rated child functioning and problem severity. Parent-rated functioning scores increased from M = 42.94 at pre-treatment to M = 45.52 at post-treatment (t = 4.70, p < .001), clinician-rated functioning scores increased from M = 43.44 at pre-treatment to M = 45.38 at discharge (t = 14.96, p < .001), parent-rated problem severity decreased from M = 28.66 at pre-treatment to M = 23.04 at discharge (t = −8.53, p < .001) and clinician-rated problem severity decreased from M = 28.51 at intake to M = 25.56 at discharge (t = −21.24, p < .001). The percentage of clinically significant change in scores for each measures was reported as follow: 13% for parent-rated functioning, 8.4% for clinician-rated functioning, 19.1% for parent-rated problem severity and 10.4% for clinician-rated problem severity	EMPS improved psychological outcomes and social functioning and led to clinically significant results for some children	Critical
Winsberg et al. (1980), USA	RCT	CYP with severe behaviour disorders referred to admission	49 (84%, 16%)	5–13 (n.s.)	BRS, DESB, DCB, MAT, SESAT, PSS (in mothers), FFC	Community treatment (6 months)	Highlight on support for the parents and involvement of social services for the family. Distinguishing characteristic of the program: continuous availability of staff, persistent advocacy and treatment flexibility. Pharmacology or individual therapy provided where needed	Inpatient hospitalisation (6 months)	A significant decrease in scores for all measures was detected for all factors in the community treatment group. A decrease from M = 2.40 (SD = .69) to M = 1.95 (SD = .81) was reported on the BRS aggressivity scale (t = 2.58, p < .05), from M = 2.61 (SD = .75) to M = 2.07 (SD = .71) on the BRS inattentiveness scale (t = 3.53, p < .01), and from M = 3.18 (SD = .72) to M = 2.35 (SD = .78) on the BRS hyperactivity scale (t = 4.27, p < .01). A decrease from M = .85 (SD = .69) to M = .48 (SD = .83) was detected on the DESB (t = 2.58, p < .05) and a decrease from M = 1.93 (SD = 1.26) to M = 1.32 (SD = 1.24) was reported on the DCB (t = 2.22, p < .05). For the hospitalisation group, pre- to post-treatment differences were not significant on any scale, apart from BRS inattentiveness scale where the scores decreased from M = 1.81 (SD = .69) to M = 1.49 (SD = .41) (t = 2.32 p < .05). The time x treatment group interaction on these measures was not investigated. Patients from both groups reported significant improvements in reading and arithmetic by end of treatment in comparison to intake (p < .05), but the gain ratio (the change between the pre- and post-treatment scores divided by number of school months attended) did not differ significantly between the two treatment groups (p > .05). No significant time or time x group differences were reported for mother’s mental health on the PSS or the FFC domains	Community treatment was reported to improve more psychological symptoms than hospitalisation, however no statistical tests were conducted to investigate the difference in change between the two groups. Both groups reported similar achievements in arithmetic and reading by the end of treatment and parental mental health was not impacted (neither positively nor negatively) by either of the two treatments	High
Exclusively clinic-based interventions, including day treatment
Asarnow et al. (2015), USA	Uncontrolled pre-post study	Adolescent suicide attempters	35 (14%, 86%)	n.s. (14.89, 1.60)	NIMH DISC-IV, HASS, CES-D, BHS, SAS	SAFETY program (M total sessions = 10.14)	Based on cognitive-behavioural techniques, aims to enhance safety and reduce suicide risk. Included individual, parental and family sessions	N/A	Significant pre-treatment to follow-up differences were reported on all scales. HASS suicide attempt scores decreased from M = 0.89 (SD = 1.86) to M = 0.13 (SD = 0.34) (t = 2.42, p = .019, d = .64); HASS active suicide behaviour and ideation decreased from M = 3.71 (SD = 4.42) to M = 1.81 (SD = 2.69) (t = 2.63, p = .019, d = .59); scores on the HASS passive suicide ideation decreased from M = 12.69 (SD = 9.79) to M = 9.19 (SD = 10.14) (t = 2.56, p = .016, d = .39); total HASS scores decreased from M = 16.40 (SD = 13.52) to M = 11.04 (SD = 12.05) (t = 2.70, p = .011, d = .46); CES-D youth scores decreased from M = 24.54 (SD = 12.33) to M = 13.69 (SD = 9.83) (t = 4.53, p < .001, d = .91); CES-D parent scores decreased from M = 20.26 (SD = 13.34) to M = 10.86 (SD = 8.55) (t = 3.47, p = .002, d = .71); BHS scores decreased from M = 8.86 (SD = 5.70) to M = 3.94 (SD = 3.79) (t = 5.58, p < .001, d = 1.01); SAS total scores decreased from M = 41.96 (SD = 7.07) to M = 32.53 (SD = 7.26) (t = 6.13, p < .001, d = 1.27); SAS school scores decreased from M = 13.90 (SD = 4.94) to M = 10.37 (SD = 3.57) (t = 3.53, p = .002, d = .90); SAS peer scores decreased from M = 17.26 (SD = 4.60) to M = 12.78 (SD = 3.54) (t = 5.36, p < .001, d = 1.11); SAS family scores decreased from M = 14.02 (SD = 3.61) to M = 11.45 (SD = 3.83) (t = 2.79, p = .009, d = .66); SAS spare time scores decreased from M = 5.15 (SD = 1.76) to M = 4.58 (SD = 1.57) (t = 2.76, p = .01, d = .52)	The SAFET program was reported to be effective in improving all clinical, functioning and family outcomes	Moderate
Greenfield et al. (1995), Canada	Cohort external historical retrospective control group	CYP in crisis referred from the emergency department	980 (n.s.)	n.s.	Admission rate	Emergency room follow-up team (ERFUT)	Immediate, intensive (daily if needed), short-term, family and psycho-dynamically oriented treatment in addition to other interventions	CYP presenting to the emergency room in crisis before the implementation of the service	A 16% reduction in the proportion of patients admitted was recorded after the implementation of the ERFUT in comparison to a period before its implementation: p < .001. Less patients were hospitalised after the implementation (n = 118, 21%), in comparison to before (n = 152, 37%). A decrease was also reported on the number of people subsequently returning to the emergency room after the implementation of the ERFUT (n = 16, 2.82%) in comparison to before (n = 19, 4.61%), but this difference did not reach statistical significance. No statistical differences were reported between the two study groups in the mean number of return emergency room visits per patient and the number of hospitalisations per patient after a second emergency room visit. No difference was reported in the number of return visits to the emergency room between the patients referred to the ERFUT and the patients who attended the emergency room but were not referred to the ERFUT in the same period	In comparison to a period before its implementation, ERFUT was associated with a decrease in admissions for CYP presenting to the emergency department in psychological crisis	Serious
Silberstein et al. (1968), USA	RCT	Psychotic children and adolescents that require psychiatric hospitalisation	48 (69%, 31%)	4.16–17 (10.33, n.s.)	Rate of inpatient admission, hospitalisation requests, police difficulties, out of regular school placements	Parental counselling with or without medication (1 hr/week)	n.s.	No counselling with or without medication	Most of the patients were maintained in the community and no significant differences were reported between the 4 groups in regard to the number of patients hospitalised (p > .05). The number of patients who successfully avoided hospitalisation in each group were as follows: parental counselling + medication group - n = 11 (N = 12, 91.7%); parental counselling + placebo - n = 11 (N = 12, 91.7%); no counselling + medication - n = 14 (N = 14, 100%); no counselling + placebo - n = 10 (N = 10, 100%). No significant group differences occurred for amount of patients who did not provoke hospitalisation requests, did not get into police difficulties and remained in their regular classroom: parental counselling + medication (n = 11, n = 9, n = 8 out of N = 12), parental counselling + placebo (n = 11, n = 10, n = 9 out of N = 12), no counselling + medication (n = 13, n= 14, n = 11 out of N = 14), no counselling + placebo (n = 10, n = 10, n = 8 out of N = 10)	The majority of the patients in the trial were maintained in the community, did not provoke hospitalisation requests, did not get into police difficulties and remained in their regular classroom. Neither parental counselling nor medication proved to be more effective in comparison to each other or in comparison to no treatment	High
Kiser et al. (1996) USA	Uncontrolled pre-post	CYP moderately to severely affected by a diagnosable psychiatric disorder	114 (n.s.)	5–18 (11.6, n.s.)	CBCL, YRS, utilization of mental health services. Intake and follow-up questionnaire (parent report of child functioning), FAD	Partial hospitalisation (12–397 days, M = 115.9)	Individual therapy, family therapy, group psychotherapy, psychoeducational groups	N/A	Treatment significantly decreased scores on all CBCL subscales from intake to follow-up apart from sex problems (from M = 59.36 to M = 55.92, t = 1.33, p = .195): withdrawn (from M = 63.72 to M = 57.95, t = 5.25, p < .001), somatic complaints (from M = 61.47 to M = 58.08, t = 3.11, p = .003); anxious/depressed (from M = 65.81 to M = 61.02, t = 3.95, p < .001); social problems (from M = 65.29 to M = 62.69, t = 2.70, p = .008); thought problems (from M = 65.44 to M = 59.67, t = 5.66, p < .001); attention problems (from M = 69.26 to M = 64.29, t = 4.28, p < .001); delinquent problems (from M = 67.01 to M = 64.12, t = 2.49, p = .015); aggressive behaviour (from M = 70.26 to M = 64.35, t = 4.49, p < .001); total problems (from M = 70.08 to M = 63.14, t = 6.24, p < .001); internalising (from M = 65.16 to M = 58.59, t = 4.90, p < .001); externalising (from M = 68.82 to M = 63.34, t = 4.84, p < .001). Treatment significantly decreased scores on all YSR subscales from intake to follow-up: withdrawn (from M = 59.62 to M = 55.80, t = 2.91, p = .005), somatic complaints (from M = 61.02 to M = 56.60, t = 2.76, p = .008); anxious/depressed (from M = 61.34 to M = 55.94, t = 3.95, p < .001); social problems (from M = 59.76 to M = 55.76, t = 2.38, p = .021); thought problems (from M = 60.36 to M = 55.46, t = 3.28, p = .002); attention problems (from M = 61.50 to M = 56.54, t = 2.89, p = .006); delinquent problems (from M = 64.06 to M = 59.60, t = 3.77, p < .001); aggressive behaviour (from M = 62.58 to M = 57.56, t = 3.59, p < .001); sex problems (from M = 62.83 to M = 54.80, t = 4.66, p < .001); total problems (from M = 63.44 to M = 54.04, t = 5.58, p < .001); internalising (from M = 60.30 to M = 51.86, t = 4.94, p < .001); externalising (from M = 63.44 to M = 56.10, t = 4.90, p < .001). Treatment significantly improved parent-rated child functioning levels from intake to follow-up in the following domains: school suspensions (from 39% to 36%, χ² = 8.78, df = 1, p < .01), child/adolescents is a good quality friend (from 65% to 88%, χ² = 6.45, df = 1, p < .05), incarcerated (from 4.7% to 6.3%, χ² = 19.6, df = 1, p < .01), trouble with police (from 13.4% to 16.4%, χ² = 11.6, df = 1, p < .01). The following parent-rated child functioning dimensions did not reach statistical significance from intake to follow-up: school (grade C or above, students failing, conduct: satisfactory or excellent); peer relations (well-adjusted/somewhat adjusted socially, many friends); community integration (on probation while for the eligible for work/holding jobs, no statistical test was conducted). For the parent-rated FAD, treatment was associated with a significant change from intake to follow-up in the following subscales: roles (from M = 2.50 to M = 2.38, t = 2.68, p = .009), behaviour control (from M = 1.88 to M = 1.73, t = 3.41, p < .001) and a marginally significant effect in affective involvement (from M = 2.34 to M = 2.22, t = 1.98, p = .051). The intake-follow-up difference did not reach significance in: problem solving, communication, affective responsiveness, general functioning. For the child-rated FAD, treatment was associated with a significant change from intake to follow-up in the following subscales: Affective involvement (from M = 2.60 to M = 2.43, t = 2.24, p = .030) and behaviour control (from M = 2.18 to M = 1.92, t = 3.48, p < .001). The intake-follow-up difference did not reach statistical significance in: problem solving, communication, roles, affective responsiveness and general functioning. Use of inpatient treatment decreased from 35.1% at intake to 10.7% at follow-up	The partial hospitalisation was successful in improving all clinical outcomes (apart from sex problems as rated by the child) and some school, peer relations and community integration functioning outcomes. Both parents and children reported that affective involvement and behaviour control improved in the family by end of treatment. The treatment also decreased the use of mental health inpatient services	Critical

Note: CBCL = Child Behaviour Checklist; GSI-BSI = The Global Severity Index of the Brief Symptom Inventory; BSI = Brief Symptom Inventory; PEI = Personal Experiences Inventory; FFS = Family, Friend and Self Scale; HSC = Hopelessness Scale for Children; YRBSS = Youth Risk Behaviour Survey; SGKJ = Skala zur Gesamtbeurteilung von Kindern und Jugendlichen; MEI = Mannheim Parent Interview; SRD = Self-report Delinquency Scale; FACES-III = Family Adaptability and Cohesion Evaluation Scales - Third Edition; SSQ = Social Support Questionnaire; SCIS = Standardized Client Information System; SSRS = Social Skills Rating System; The Ohio Scale; BRS = The Conners Behaviour Rating Scale; DESB = The Devereux Elementary School Behaviour Rating Scale; DCB = Devereux Child Behaviour Rating Scale; MAT = Metropolitan Achievement Test; SESAT = Stanford Early School Achievement Test; PSS = Psychiatric Status Schedule; FFC = Family Functioning Checklist; YRS = Youth Self-Report; FAD = McMaster Family Assessment Device; Y-OQ = Youth Outcome Questionnaire; NIMH DISC-IV = NIMH Diagnostic Interview Schedule for Children Version IV; Columbia Suicide History Form; HASS = Harkavy–Asnis Suicide Survey; CES-D = Center for Epidemiological Studies-Depression Scale; BHS = Beck Hopelessness Scale; SAS = Social Adjustment Scale.

Included papers did not allow sufficiently robust information to perform meta-analysis, and so, we present findings here narratively, with interventions grouped by: (1) Single-session interventions for emergency department crisis presentations and (2) Community-based crisis interventions (as (i) exclusively in-home interventions, (ii) interventions outside of the home but outside clinics and (iii) exclusively clinic-based outpatient interventions, including intensive day treatment).

Single-session interventions for emergency department crisis presentations

We found three papers which evaluated the effectiveness of single-session urgent response consultations in emergency departments. Two papers were service evaluations (Gillig, 2004; Parker et al., 2003), and one paper used a pre-intervention historical/retrospective control group (Wharff et al., 2012). One paper was at critical risk of bias (Gillig, 2004), one at serious risk of bias (Parker et al., 2003) and one at low risk of bias (Wharff et al., 2012). Gillig (2004) investigated the effects of offering an emergency evaluation interview and a brief therapeutic intervention at a maximum of 24 hours after CYP presentation, using a supportive, reality-based and present-focused therapeutic approach. They reported that only 10% (n = 5) of the patients seen by the emergency consultation team were hospitalised right after the input was received, no patients were hospitalised in the month following the input and 4.2% (n = 2) patients were hospitalised 6 months later. Parker et al. (2003) analysed a Rapid Response Model (RRM) which offered consultations to CYP in acute mental health crises within 48 hours of their presentation to the ED, focussing on the crisis and risk. They used two sites: one site studied outcomes over 4 years (with pre-RRM, during RRM implementation, post-RRM termination and during RRM re-implementation as four time periods) and another over 2 years (pre-RRM and post-RRM as two time periods). Findings were mixed. For the first site, no change was reported in the number of admissions over the four time periods but RRM stage had a significant effect on the monthly average length of inpatient stay: F(1, 42) = 3.1, p < .05). For the second site, there was a reported decrease in the percentage of admissions, with a reduction from 22% at pre-RRM to 2% at post-RRM (χ² = 31.6, N = 340, d.f. = 1, p < .001). Wharff et al. (2012) investigated a single-session family-based crisis intervention (FBCI) for suicidal adolescents, delivered in a paediatric ED and focussing on constructing a safety plan and encouraging family communication. They reported a reduction in numbers admitted during the implementation of FBCI (55%–35%, p < .0001).

Community-based treatments

We found fourteen papers investigating the effectiveness of community-based treatments for CYP presenting in crisis. Nine were of home interventions, three were community interventions outside of the home but outside clinics and two were exclusively clinic-based outpatient interventions, including day treatment.

Exclusively in-home interventions.

We found nine papers studying in-home interventions – five studying multisystemic therapy (MST) and four papers of other family-based interventions in the home.

Five papers investigated the effectiveness of multisystemic therapy (MST) delivered at home and which combined a range of therapeutic approaches. All five papers were RCTs, although four were in effect different outcomes from one single trial (Henggeler et al., 1999, 2003; Huey et al., 2004; Schoenwald et al., 2000). The risk of bias assessment revealed that four papers were at low risk of bias (Henggeler et al., 1999, 2003; Huey et al., 2004; Rowland et al., 2005; Schoenwald et al., 2000) while one raised some concerns (Rowland et al., 2005).

The effects of MST on admission rates and length of stay were investigated by two papers in two separate trials (Rowland et al., 2005; Schoenwald et al., 2000). In one RCT, in a sample of CYP in mental health crisis assessed to require an admission, MST was compared to hospitalisation (Schoenwald et al., 2000). At the end of treatment, 44% of those assigned to the MST group (approximately 4 months post-referral) were admitted to hospital and mean length of stay was lower than the hospitalised control group (mean days 2.39 vs. 8.82, t = 3.91, p = .001). In a second RCT, CYP at risk of out-of-home placement (e.g. inpatient hospitalisation, group homes and foster care) were randomly assigned to receive either MST or usual care (Rowland et al., 2005). The study did not report on the number of patients hospitalised following the intervention in either group. However, number of days spent in out-of-home placement per month were lower in the intervention group (mean days 3.75 vs. 11.83, F = 5.68, p = .025).

Potential psychological benefits of MST were investigated in four papers, three reporting outcomes from a single trial comparing MST to inpatients, and one from another trial comparing MST to usual care. Compared to hospitalisation (Henggeler et al., 1999; Huey et al., 2004), MST was reported to have superiority in improving a number of psychological measures. Post-intervention changes were superior compared to admission controls for the caregiver-rated externalising symptoms (F(1,102) = 6.55, p < .011), teacher rated externalising symptoms (F(1, 45) = 4.10, p < .048), youth-reported family adaptability (F(2, 220) = 3.28, p = .039), caregiver-rated family cohesion (F(2, 206) = 6.56, p < .001) and youth-reported suicide attempts (t = 3.60, p < .001). However, a further paper of 12–16 month follow-up revealed that generally superiority was not sustained (Henggeler et al., 2003). Change in self-esteem was initially superior in the hospitalised group (F(1, 109) = 7.72, p = .006); however, again this was not sustained at 12–16-month follow-up. For MST compared to treatment as usual (Rowland et al., 2005), there was superior change in youth-rated externalising symptoms (F(1, 25) = 4.62, p = .041) and internalising symptoms (F(1,28) = 6.05, p = .021) for the MST group.

We found four papers of other family-based interventions delivered at home which reported on psychological outcomes. One was an RCT (Wilmshurst, 2002), one was a study using a matched sample control group (Schmidt et al., 2006) and two were uncontrolled studies investigating pre- to post-treatment changes (Lay et al., 2001; Mosier et al., 2001). Bias assessment revealed that two papers were at serious risk of bias (Lay et al., 2001; Mosier et al., 2001), one paper was at moderate risk (Schmidt et al., 2006) while the other paper raised some concerns (Wilmshurst, 2002). Neither paper described proportions of CYP receiving the alternative interventions who required admission. In the RCT, Wilmshurst (2002) reported that the in-home treatment was superior to a 5-day residential programme in improving internalising symptoms at follow-up (F (2,62) = 3.92 and p = .025). Comparing the intervention to a matched control group receiving hospitalisation, Schmidt et al. (2006) reported that by the end of treatment, hospitalisation was superior at improving psychological symptoms related to major DSM-IV diagnoses (p < .001), child-rated behaviour (p = .02), parent-rated behaviour (p = .03) and increased functioning in more domains (family, peers, interests and autonomy) than the in-home treatment (family, interests and autonomy). Lay et al. (2001) compared pre- and post-treatment outcomes in a sample of CYP requiring an intervention as an alternative to admission presenting with high risk externalising behaviours. Improvements were reported in the total symptoms related to major DSM-IV diagnoses (p < .001) and child-rated psychosocial functioning (p < .001). Mosier et al. (2001) also compared pre- and post-treatment outcomes of an in-home famility therapy for CYP requiring restrictive and intensive mental health treatment. In comparison to pre-treatment, post-treatment improvements were reported in clinical symptoms for a number of CYP, with some being reported to have recovered. No statistical tests were conducted for this comparison. The end of treatment mean clinical symptoms of the group was compared to the normative scores of patients receiving inpatient/outpatient treatment, but no significant differences were reported.

Interventions outside of the home but outside of hospital clinics.

We found three papers which evaluated the effectiveness of community interventions outside of the home but away from clinic settings. The stated aim of these interventions was to stabilize the patients by offering an array of services, delivered flexibly in the community depending on need (e.g. schools). One paper was an RCT (Winsberg et al., 1980) and two papers were service evaluations (Darwish et al., 2006; Vanderploeg et al., 2016). The risk of bias assessment revealed that one paper was at high risk of bias (Winsberg et al., 1980), one was at critical risk (Vanderploeg et al., 2016) and one was at serious risk (Darwish et al., 2006). Only one of these papers, Darwish et al. (2006), reported on admission outcomes for their intervention, reporting that their community intensive therapy decreased admissions compared to a pre-intervention historical group (decreasing to one person per year over 5 years versus six people per year at pre-implementation, no statistics presented). Two papers reported on psychological outcomes. Winsberg et al. (1980) reported pre- and post-intervention scales and hospitalisation on a group of CYP in crisis, on a range of psychological parameters. Post-intervention, the community treatment improved symptoms of aggression (t = 2.58, p < .05), inattentiveness (t = 3.53, p < .01), hyperactivity (t = 4.27, p < .01), school behaviour (t = 2.58, p < .05), and overall child behaviour (t = 2.22, p < .05). In comparison, hospitalisation improved only inattentiveness (t = 2.32 p < .05). There was however no comparison of differences between the interventions and hospitalised groups. Vanderploeg et al. (2016) studied changes in a sample of CYP receiving emergency mobile psychiatric services however they did not compare their outcomes to a control group. They reported that improvements were achieved in parent-rated problem severity (t = −8.53, p < .001), clinician-rated problem severity (t = −21.24, p < .001) parent-rated child functioning (t = 4.70, p < .001) and clinician-rated child functioning (t = 14.96, p < .001).

Exclusively clinic-based interventions, including intensive day treatment.

We found four papers which evaluated the effects of interventions in clinic-based settings (one including intensive day treatment) in CYP presenting in crisis as alternatives to hospitalisation. One paper was an RCT (Silberstein et al., 1968), one paper used a matched sample control group (Greenfield et al., 1995) and two papers were uncontrolled pre–post-intervention studies (Asarnow et al., 2015; Kiser et al., 1996). The risk of bias assessment revealed that one paper was at moderate risk of bias (Asarnow et al., 2015), one at high risk of bias (Silberstein et al., 1968), one at serious risk of bias (Greenfield et al., 1995) and one at critical risk (Kiser et al., 1996).

Silberstein et al. (1968) compared 4 separate groups of CYP presenting with psychosis receiving: (1) parental counselling with or (2) without medication; (3) no counselling plus medication; and (4) no counselling plus placebo. There were no differences in rates of admissions between groups. Greenfield et al. (1995) investigated the outcomes of implementing an emergency room follow-up team and reported that in comparison to a period before its implementation, the admission rate of CYP presenting to the emergency room in psychiatric crisis decreased by 16% (p < .001). No statistical difference was reported between the two groups in the number of hospitalisations occurring per patient after a second emergency room visit.

Kiser et al. (1996) reported on psychological outcomes of an outpatient day program for CYP in mental health crisis as an alternative to admission. Post-intervention, improvements were reported in being withdrawn (parent report: t = 5.25, p < .001; CYP report: t = 2.91, p = .005), somatic complaints (parent report: t = 3.11, p = .003; CYP report: t = 2.76, p = .008), anxious/depressed (parent report: t = 3.95, p < .001; CYP report: t = 3.95, p < .001), social problems (parent report: t = 2.70, p = .008; CYP report: t = 2.38, p = .021), thought problems (parent report: t = 5.66, p < .001; CYP report: t = 3.28, p = .002), attention problems (parent report: t = 4.28, p < .001; CYP report: t = 2.89, p = .06), delinquent behaviour (parent report: t = 32.49, p = .015; CYP report: t = 3.77, p < .001), aggressive behaviour (parent report: t = 4.49, p < .001; CYP report t = 3.59, p < .001); sex problems (significant for CYP report only: t = 4.66, p < .001), total problems (parent report: t = 6.24, p < .001; CYP report t = 5.58, p < .001), internalising (parent report: t = 4.90, p < .001; CYP report: t = 4.94, p < .001) and externalising (parent report: t = 4.84, p < .001; CYP report t = 4.90, p < .001). Both parents and CYP also reported that at follow-up, family functioning was improved in the following domains: roles (parent report only: t = 2.68, p = .009), affective involvement (CYP report only: t = 2.24, p = .03) and behaviour control (parent report: t = 3.41, p = .001; CYP report: t = 3.48, p = .001). Follow-up improvements were also reported in rates of school suspensions (from 39% to 36%, χ² = 8.78, df = 1, p < .01) and CYP being a good quality friend (from 65% to 88%, χ² = 6.45, df =1, p < .05), while a deterioration occurred in the CYP’s legal status, with increased incarceration rates (from 4.7% to 6.3%, χ² = 19.6, df = 1, p < .01) and more trouble with the police at follow-up (from 13.4% to 16.4%, χ² = 11.6, df = 1, p < .01). Asarnow et al. (2015) reported on psychological outcomes of an outpatient intervention (the SAFETY program) delivered to adolescent suicide attempters. They reported pre- to post-treatment improvements in all outcomes measured: suicide attempts (t = 2.42, p = .019, d = .64), active suicide behaviour and ideation (t = 2.63, p = .019, d = .59), passive suicide ideation (t = 2.56, p = .016, d = .39), total suicidality score (t = 2.70, p = .011, d = .46), CYP reported youth depression symptoms (t = 4.53, p < .001, d = .91), parent-reported parental depression symptoms (t = 3.47, p = .002, d = .71), hopelessness (t = 5.58, p < .001, d = 1.01), social adjustment total score (t = 6.13, p < .001, d = 1.27), social adjustment at school (t = 3.53, p = .002, d = .90), social adjustment with peers (t = 5.36, p < .001, d = 1.11), social adjustment with the family (t = 2.79, p = .009, d = .66) and social adjustment in the spare time (t = 2.76, p = .01, d = .52).

Discussion

In this systematic review of studies of alternatives to inpatient admissions for CYP presenting with a mental health crisis, we found a range of published studies on interventions in different settings. We found studies describing interventions in emergency departments, the home, other community settings and hospital-based clinics. In general, the level of evidence was poor with less than half of included studies RCTs, of which only half were considered of low risk of bias in bias assessments. Studies also varied with regard to consistency of reporting on measures on preventing admissions and psychological outcomes. This meant that robust data for meta-analysis was insufficient. The greatest level of evidence came from home-treatments, in particular MST. The studies we found for MST offered treatment for 3–6 months and used family and behavioural therapy techniques to address the strengths and weaknesses of the CYP and their environment (i.e. family, peers and school) in a highly individualised treatment plan. MST was reported as improving a range of psychological parameters associated with risk for CYP (such as suicide attempts) and benefits for families (adaptation and cohesion though not maintained at 4 months); and though a large proportion of CYP appeared to still ultimately be admitted (in one study 44%), there was evidence that length of stay from these admissions was reduced compared to admission alone. We found some evidence suggesting that brief emergency department-based interventions could have a beneficial impact on admission rates. These interventions consisted of either a single treatment session or support over a short period of time (i.e. 24 hours), and used either brief interviews to understand the crisis and risk, or cognitive-behavioural and family therapy techniques for psychoeducation, therapeutic readiness and safety planning. However, none of these studies were RCTs, and there was no information on impact upon psychological parameters in any paper. Evidence for other community interventions, and clinic-based interventions were scarce, and generally of low quality. However, we found some evidence for reduction in admission rates and improvements in post-intervention symptom severity, child and family functioning, although these were not compared to outcomes of control groups.

Our review did not find sufficient amount of quality data to recommend a specific type of intervention for CYP presenting in crisis, a similar conclusion to the two other systematic reviews on this topic which included searches from over 6 years ago (Kwok et al., 2016; Shepperd et al., 2009). However, the evidence we have presented provides useful information for the development of new and existing services, including the potential for mix-models of care, or ‘menus’ of care for individual patients’ needs by understanding variable benefits of different models. Given the challenges associated with the complexity of such CYP presenting in crisis, especially with regard to risk, the limited availability of good quality data is perhaps understandable. However, with such presentations increasing, and pressure on inpatient units rising (Children’s Commissioner, 2020), this is clearly an area which needs to see an increase in research as a priority. With new emphasis on improvement for CYP with mental health disorders, especially those presenting in crisis (Ougrin et al., 2018), it is likely that new models will develop. It is important that as they do so, they are robustly evaluated, in particular with comparison to controls (including for example pre-intervention controls), with consistent measurement and reporting of success at reducing absolute numbers of admissions, duration of admissions and also psychological impacts for CYP and families. Studies should also report detail on change between groups of intervention and control, for a large proportion of studies we found in our review presented only pre and post values for intervention and control separately, and this impedes the opportunity for an appropriate pooling of studies in meta-analysis (Higgins et al., 2017).

Beyond the limitations which we have highlighted above, our review has a number of strengths. We used an a priori search strategy of multiple databases, with defined inclusion and exclusion criteria for the studies and two independent researchers performed searches. We also investigated on a large range of intervention types by also including non-RCTs, in comparison to previous reviews that looked at RCTs only. We reported on all outcomes described and had two independent researchers to conduct thorough bias assessments, with a third providing final adjudication.

In conclusion, although we found a range of interventions in different settings, the quality of studies was insufficient to allow for an overall recommendation. Interventions using multisystemic therapy at home had the best quality, with evidence suggesting benefits around avoiding admissions, length of admission and psychological outcomes. However, these interventions generally failed to show long-term effects. New models of care should be robustly evaluated using consistent outcomes.

Supplemental Material

sj-pdf-1-ccp-10.1177_13591045211044743 – Supplemental material for Alternatives to mental health admissions for children and adolescents experiencing mental health crises: A systematic review of the literature

Supplemental material, sj-pdf-1-ccp-10.1177_13591045211044743 for Alternatives to mental health admissions for children and adolescents experiencing mental health crises: A systematic review of the literature by Denisa A Clisu, Imogen Layther, Deborah Dover, Russell M Viner, Tina Read, David Cheesman, Sally Hodges and Lee D Hudson in Clinical Child Psychology and Psychiatry

Footnotes

Declaration of conflicting interests

The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Funding

The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This article is supported by Great Ormond Street Hospital Charity.

ORCID iDs

Denisa A Clisu

Lee D Hudson

Supplemental material

Supplemental material for this article is available online.

Appendix A

Search terms used for all databases: [(children and adolescents OR children OR adolescents OR youth) AND mental health AND (crisis OR crises)] AND [emergency department OR a&e OR ‘alternatives to hospital admission’ OR ‘home treatment’ OR ‘community based crisis’ OR ‘alternative care’ OR ‘short stay hospital’ OR ‘acute day hospital’ OR ‘acute ward’ OR ‘crisis houses’ OR ‘family based treatment’ OR ‘multisystemic therapy’ OR ‘crash pad*’ NOT (homeless OR homelessness)].

Appendix B

Table B2.

Results of risk of bias assessment for non-randomised trials using the ROBINS-I tool.

Reference	Confounding	Notes	Selection of participants	Notes	Classification of interventions	Notes	Deviations from intended intervention	Notes	Missing data	Notes	Measurement of outcome	Notes	Selection of reported results	Notes	Overall bias
Asarnow et al. (2015), USA	Moderate	Single group study but standardization used to control for possible confounders	Moderate	Some pre-established eligibility criteria used	Not applicable	Single group design	Low	No deviations mentioned	Moderate	Although substantial missing data were reported, the authors used an appropriate statistical analysis to account for it	Low	Validated and reliable outcome measures used	Low	No potential bias identified	Moderate
Darwish et al. (2006), UK	Critical	Retrospective control group and no statistical analysis conducted to determine baseline group differences	Serious	No pre-established eligibility criteria used	Moderate	Retrospective study of different time periods in which patients attending a clinic either received or did not receive the new intervention	Low	No deviations mentioned	Low	No significant missing data reported	Low	Validated and reliable outcome measures used	Low	No potential bias identified	Serious
Gillig (2004), USA	Critical	Single group design – potential for confounding	Serious	No pre-established eligibility criteria used	Not applicable	Single group design	Low	No deviations mentioned	Low	No significant missing data report	Low	Validated and reliable outcome measures used	Low	No potential bias identified	Critical
Greenfield et al. (1995), Canada	Critical	Retrospective control group and no statistical analysis conducted to determine baseline group differences	Serious	No pre-established eligibility criteria used	Moderate	Retrospective study of different time periods in which patients attending a clinic either received or did not receive the new intervention	Low	No deviations mentioned	Low	No significant missing data reported	Low	Validated and reliable outcome measures used	Low	No potential bias identified	Serious
Kiser et al. (1996), USA	Critical	Single group design – potential for confounding	Serious	No pre-established eligibility criteria used	Not applicable	Single group design	Low	No deviations mentioned	Low	No significant missing data reported	Low	Validated and reliable outcome measures used	Low	No potential bias identified	Critical
Lay et al. (2001), Germany	Critical	Single group design – potential for confounding	Low	Clear pre-established eligibility criteria used	Not applicable	Single group deign	Low	No deviations mentioned	Low	No significant missing data reported	Low	Validated and reliable outcome measures used	Low	No potential bias identified	Serious
Mosier et al. (2001), USA	Serious	Single group design but statistical analysis conducted to determine baseline group differences in comparison to normative scores on the same scale for a sample receiving inpatient/outpatient treatment	Serious	No pre-established eligibility criteria used	Not applicable	Single group design	Low	No deviations mentioned	Moderate	Although substantial missing data was reported, the authors used an appropriate statistical analysis to account for it	Low	Validated and reliable outcome measures used	Low	No potential bias identified	Serious
Parker et al. (2003), Canada	Critical	Retrospective study – potential for confounding	Serious	No pre-established eligibility criteria used	Moderate	Retrospective study of different time periods in which patients attending a clinic either received or did not receive the new intervention	Low	No deviations mentioned	Low	No significant missing data reported	Low	Validated and reliable outcome measures used	Low	No potential bias identified	Serious
Schmidt et al. (2006), Germany	Moderate	Although matched samples were used in the trial, the authors could not recruit the same number of patients in the control group as the experimental condition	Low	Clear pre-established eligibility criteria used	Low	Treatment and control groups used	Low	No deviations mentioned	Low	No significant missing data reported	Low	Validated and reliable outcome measures used	Low	No potential bias identified	Moderate
Vanderploeg et al. (2016), USA	Critical	Single group design – potential for confounding	Serious	No pre-established eligibility criteria used	Not applicable	Single group design	Low	No deviations mentioned	Low	No clear information on whether there was any missing data or not	Low	Validated and reliable outcome measures used	Low	No potential bias identified	Critical
Wharff et al. (2012) USA	Low	Matched control group used, and statistical analysis were conducted to determine differences between groups at baseline. No differences were found	Low	Clear pre-established eligibility criteria used	Moderate	Matched retrospective comparison group	Low	No deviations mentioned	Low	No significant missing data reported	Low	Validated and reliable outcome measures used	Low	No potential bias identified	Low

Author biographies

Denisa Clisu is a research assistant at the GOS UCL Intitute of Child Health.

Imogen Layther worked as a research assiatnt at Great Ormond Street Hospital.

Deborah Dover has over ten years experience as a Consultant in Paediatric Liaison Psychiatrist at RFH Barnet. Her special interests include quality improvement, working with physical conditions, supporting young people in crisis and suicide prevention. She is Deputy Medical Director for Barnet, Enfield and Haringey Mental Health Trust, has recently graduated as an NHSEI QSIR teaching associate and has completed the Nye Bevan programme in executive leadership.

Russell Viner is a professor of adolesent Health at the UCL GOS Institute of Child Health. He is a former president of the Royal College of Paediatrics and Child Health.

Tina Read is psychiatrist, and trust Wide Lead for CAMHS, Barnet, Enfield and Haringey Mental Health Trust.

David Cheesman has over 19 years as a board director in the NHS organisations. He is Director of Strategy & Transformation at Barnet Enfield & Haringey Mental Health NHS Trust – a large, complex hospital serving people in North Central London. David was previously Programme Director for Guy’s & St Thomas’ (GSTT) Comprehensive Cancer Centre. Prior to joining GSTT, David was Director of Strategy at the North West London Hospitals NHS Trust, following three years at Mid Essex Hospital Services NHS Trust where he was Executive Director of Operations. He had previously been on the Board of Whipps Cross University Hospital 2002 to 2006 as Director of Acute Services and then Director of Strategy and Performance.

Sally Hodges is Clinical Chief Operating Officer of the Tavistock and Portman NHS Trust in London. Prior to taking up this role she was Director of CYAF. Before that she was Associate Clinical Director of Complex Needs in CYAF, and the Patient and Public Involvement (PPI) lead for the Trust. Sally is a Consultant Clinical Psychologist, and has been working with the Trust since May 1996, specialising in children and young people with learning and developmental disabilities. She also holds a Leadership MSc from the University of Birmingham and the NHS Leadership Academy.

Lee Hudson is a clincial associate professor at the GOS UCL Institute of Child Health and an honorary consultant paediatrician at Great Ormond Street Hospital.

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