SchrollMMunckO.Estimation of peripheral atherosclerotic disease by ankle blood pressure measurements in a population study of 60 year old men and women. J Chron Dis1982; 34: 261–69.
2.
CriquiMHFronekABarrett-ConnorEKlauberMRGabrielSGoodmanD.The prevalence of peripheral arterial disease in a defined population. Circulation1985; 71: 510–15.
3.
HaleWEMarksRGMayFEMooreMTStewartRB. Epidemiology of intermittent claudication: Evaluation of risk factors. Age Aging1988; 17: 57–60.
4.
AgnerE.Natural history of angina pectoris, possible intermittent claudication and intermittent claudication during the eight decade. Acta Med Scand1981; 201: 271–76.
5.
KannelWBMcGeeDL. Update on some epidemiologic features of intermittent claudication: The Framingham Study. J Am Geriatr Soc1985; 33: 13–18.
6.
DormandyJMahirMAscadyGFate of the patient with chronic leg ischaemia. J Cardiovasc Surg1989; 30: 50–57.
7.
KannelWBShurtleffD.The Framingham Study. Cigarettes and the development of intermittent claudication. Geriatrics1973; 28: 61–68.
8.
KozakGPRowbothamJL. Diabetic foot disease: A major problem. KozakGP eds. Management of diabetic foot problems. Philadelphia: WB Saunders, 1984.
9.
FriedmanSAHillingHERobertsB.Etiologic factors in aortoiliac and femoropopliteal vascular disease. N Engl J Med1964; 271: 1382–85.
10.
HaycraftJB. Uber die Einwirkung eines Sekrates des officinellen Blutegels auf die Gerinnbarkeit des Blutes. Arch Exp Pathol Pharmakol1884; 18: 209.
11.
MarkwardtF.Die Isoliegrung und chemische Charakterisisierung des Hirudins. Hoppe-Seylers Z Physiol Chem1957; 308: 147–56.
12.
MarkwardtF.Hirudin as an inhibitor of thrombin. Methods Enzymol1970; 19: 924–32.
13.
GrossenbacherHAudenJBillKLierschMMarkiW.Isolation and characterization of recombinant desulphatohirudin from eyast: A highly selective thrombin inhibitor. Thromb Haemost1987; Suppl VII: 34.
14.
MeyhackBHeimJRinkHZimmermanWMarkiW.Desulphatohirudin, a specific thrombin inhibitor: Expression and secretion in yeast. Thromb Haemost1987; Suppl VII: 33.
15.
ZoldelyiPWebsterMWIFusterVRecombinant hirudin in patients with chronic stable coronary artery disease, safety, half-life and effect on coagulation parameters. Circulation1993; 88 (Part I): 2015–22.
16.
VerstraeteMNurmohamedMKienastMBiologic effects of recombinant hirudin (CGP39393) in human volunteers. J Am Coll Cardiol1993; 22: 1080–92.
17.
CannonCPMaraganoreJMLoscalzoJAnticoagulant effects of Hirulog, a novel thrombin inhibitor, in patients with coronary artery disease. Am J Cardiol1993; 71: 778–82.
18.
Skrzypczak-JankumECarperosVERavichandranKGStructure of the hirugen and hirulog-1 complexes of alpha-thrombin. J Mol Biol1992; 221: 1379–93.
19.
BourdonPJablonskiJChaoBHMaragnoreJM. Structure–function relationship of hirulog peptide interactions with thrombin. FEBS Lett1991; 294: 163–66.
20.
FoxIDawsonALoyndsPAnticoagulant activity of Hirulog™, a direct thrombin inhibitor, in humans. Thromb Haemost1993; 2: 157–63.
21.
LidonRMTherouxPJuneauMAdelmanBMaraganoreJ.Initial experience with direct antithrombin hirulog, in unstable angina. Circulation1993; 88: (Part I): 1495–501.
22.
TopolEJBonanRJewittDUse of a direct antithrombin, hirulog, in place of heparin during coronary angioplasty. Circulation1993; 87: 1622–29.
23.
WaxmanLSmithDEArcuriKEVlasukGP. Tick anticoagulant peptide (TAP) is a novel inhibitor of blood coagulation factor Xa. Science1990; 248: 593–96.
DunwiddieCTNuttEMVlasukGPSiegalPKSSchafferLW. Anticoagulant efficacy and immunogenicity of the selective factor Xa inhibitor antistatin following subcutaneous administration in the Rhesus monkey. Thromb Haemost1992; 3: 371–76.
26.
Warn-CramerBJRapaportSI. Studies the factor Xa/phospholipid-induced intravascular coagulation in rabbits. Arterioscler Thromb1993; 13: 1551–57.
27.
HaskelEJTorrSRDayKCPrevention of arterial reocclusion after thrombolysis with recombinant lipoprotein-associated coagulation inhibitor. Circulation1991; 84: 821–27.
28.
RufWEdgingtonTS. An anti-tissue factor monoclonal antibody which inhibits TFVIIa complex is a potent anticoagulant in plasma. Thromb Haemost1991; 5: 529–33.
29.
TheryCSimonnearuGMeyerG.Randomized trial of subcutaneous low molecular weight heparin VY216 (Fraxiparine) compared with intravenous unfractionated heparin in the curative treatment of submassive pulmonary embolism. Circulation1992; 85: 1380–89.
30.
HullRDRaskobGEPineoGFSubcutaneous low molecular weight heparin compared with continuous intravenous heparin in the treatment of proximal vein thrombosis. N Engl J Med1992; 326: 975–82.
31.
AlbadaJNieuwenhuisHKSixmaJJ. Treatment of acute venous thromboembolism with low molecular weight heparin (fragmin). Circulation1989; 80: 935–40.
32.
HarkerLAMalpassTWBransonHEMechanism of abnormal bleeding in patients undergoing cardiopulmonary bypass: Acquired transient platelet dysfunction associated with selective α-granule release. Blood1980; 56: 824–34.
33.
StronyJPhillipsMBrandsDAurintricarboxylic acid in a canine model of coronary artery thrombosis. Circulation1990; 81: 1106–14.
34.
YasudaTGoldHKLeinbackRCLysis of plasminogen activator-resistant platelet-rich coronary artery thrombus with combined bolus injection of recombinant tissue type plasminogen activator and antiplatelet GPIIb/IIIa antibody. J Am Coll Cardiol1990; 16: 1738–35.
35.
MusialJNiewiarowskiSRuchinskiBInhibition of platelet adhesion to surfaces of extracorporeal circuits by disintegrins: RDG-containing peptides from viper venoms. Circulation1990; 82: 261–73.
36.
SaltielRWardA.Ticlopidine: A review of its pharmacodynamics and pharmacokinetic properties and therapeutic efficacy in platelet-dependent disease states. Drugs1987; 34: 222–62.
37.
FitzgeraldGAReillyLAPedersonAK. The biochemical pharmacology of thromboxane synthase inhibition in man. Circulation1985; 72: 1194–201.
38.
MullaneKMFoinabaioD.Thromboxane synthestase inhibitors reduce infarct size by a platelet-dependent, aspirin-sensitive mechanism. Circ Res1988; 62: 668–78.
39.
SaussyDLJrMaisDeKnappDRHalushkaPV. Thromboxane A2 and prostaglandin endoperoxide receptors in platelets and vascular smooth muscle. Circulation1985; 72: 1202–207.
40.
ClubbFJSchmitzJMButlerMMEffect of dietary omega-3 fatty acid on serum lipids, platelet function, and atherosclerosis in Watanabe heritable hyperlipidemic rabbits. Arterioscler Thromb1989; 9: 529–37.
41.
SpectorAAKaduceTLFigardPHEicosapentaenoic and prostacyclin production by the cultured human endothelial cells. J Lipid Res1983; 24: 1595–604.
42.
NeedlemanPSprecherHWhitakerMOWycheA.Mechanism underlying the inhibition of platelet aggregation by eicosapentaenoic acid and its metabolites. In: SamuelssonBRamwellPWPaolettiR eds. Advances in prostaglandin and thromboxane research. New York: Raven Press, 1980.
43.
Fischer-DzogaKKuoYFWisslerRW. The proliferation effect of platelet and hyperlipidemic serum on stationary primary cultures. Atherosclerosis1983; 47: 35–45.
44.
TiellMLSussmanIIGordonPB. Suppression of fibroblast proliferation in vitro and myointimal hyperplasia in vivo by the trazolopyrimidine, Trapidil. Artery1983; 12: 33–50.
45.
Antiplatelet Trialists' Collaboration.Secondary prevention of vascular disease by prolonged antiplatelet treatment. Br Med J1988; 296: 320–33.
46.
Antiplatelet Trialists' Collaboration.Collaborative overview of randomized trials of antiplatelet therapy. Br Med J1994; 308: 81–106.