2011 ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/ SCAI/SIR/SNIS/SVM/SVS Guideline on the Management of Patients With Extracranial Carotid and Vertebral Artery Disease: Executive Summary

ACCF/AHA Task Force on Practice Guidelines. Manual for ACCF/ AHA Guideline Writing Committees: Methodologies and Policies from the ACCF/AHA Task Force on Practice Guidelines . Available at: http://assets.cardiosource.com/Methodology_Manual_for_ACC_AHA_Writing_Committees.pdfandhttp://circ.ahajournals.org/manual/. Accessed October 1, 2010.

Adams HP Jr. , del Zoppo GJ , Alberts MJ , et al. Guidelines for the early management of adults with ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups [published corrections appear in Stroke. 2007 ;38:e38 and Stroke 2007;38: e96]. Stroke. 2007 ;38:1655-711

Rashid P. , Leonardi-Bee J. , Bath P. Blood pressure reduction and secondary prevention of stroke and other vascular events: a systematic review. Stroke 2003;34:2741-8.

Sacco RL , Adams R. , Albers G. , et al. Guidelines for prevention of stroke in patients with ischemic stroke or transient ischemic attack: a statement for healthcare professionals from the American Heart Association/American Stroke Association Council on Stroke. Stroke 2006;37:577-617.

PROGRESS Collaborative Group Randomised trial of a perindoprilbased blood-pressure-lowering regimen among 6,105 individuals with previous stroke or transient ischaemic attack. Lancet 2001 ;358: 1033-41.

Lawes CM , Bennett DA , Feigin VL , et al. Blood pressure and stroke: an overview of published reviews . Stroke 2004;35:776-85.

Neal B. , MacMahon S. , Chapman N. , et al. Effects of ACE inhibitors, calcium antagonists, and other blood-pressure-lowering drugs: results of prospectively designed overviews of randomised trials. Lancet 2000;356:1955-64.

Wolf PA , D’Agostino RB , Kannel WB , et al. Cigarette smoking as a risk factor for stroke: the Framingham Study. JAMA 1988;259: 1025-9.

Shinton R. , Beevers G. Meta-analysis of relation between cigarette smoking and stroke. BMJ 1989;298:789-94.

Kawachi I. , Colditz GA , Stampfer MJ , et al. Smoking cessation and decreased risk of stroke in women. JAMA 1993;269:232-6.

Robbins AS , Manson JE , Lee IM , et al. Cigarette smoking and stroke in a cohort of U.S. male physicians . Ann Intern Med 1994;120: 458-62.

Wannamethee SG , Shaper AG , Whincup PH , et al. Smoking cessation and the risk of stroke in middle-aged men. JAMA 1995;274: 155-60.

Amarenco P. , Bogousslavsky J. , Callahan A.III et al. High-dose atorvastatin after stroke or transient ischemic attack. N Engl J Med 2006;355:549-59.

Adams RJ , Albers G. , Alberts MJ , et al. Update to the AHA/ASA recommendations for the prevention of stroke in patients with stroke and transient ischemic attack. Stroke 2008;39:1647-52.

Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. Circulation 2002;106:3143-421.

Frick MH , Elo O. , Haapa K. , et al. Helsinki Heart Study: primary-prevention trial with gemfibrozil in middle-aged men with dyslipidemia. Safety of treatment, changes in risk factors, and incidence of coronary heart disease. N Engl J Med 1987;317:1237-45.

Kris-Etherton PM , Harris WS , Appel LJ Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease. Circulation 2002;106:2747-57.

Rubins HB , Robins SJ , Collins D. , et al. , Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group. Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. N Engl J Med 1999 ;341:410-8.

Brown BG , Zhao XQ , Chait A. , et al. Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease. N Engl J Med 2001;345:1583-92.

Gerstein HC , Miller ME , Byington RP , et al. Effects of intensive glucose lowering in type 2 diabetes. N Engl J Med 2008;358:2545-59.

Patel A. , MacMahon S. , Chalmers J. , et al. Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes. N Engl J Med 2008;358:2560-72.

Colhoun HM , Betteridge DJ , Durrington PN , et al. Primary prevention of cardiovascular disease with atorvastatin in type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS): multicentre randomised placebo-controlled trial. Lancet 2004;364:685-96.

Goldstein LB , Adams R. , Alberts MJ , et al. Primary prevention of ischemic stroke: a guideline from the American Heart Association/ American Stroke Association Stroke Council: cosponsored by the Atherosclerotic Peripheral Vascular Disease Interdisciplinary Working Group; Cardiovascular Nursing Council; Clinical Cardiology Council; Nutrition, Physical Activity, and Metabolism Council; and the Quality of Care and Outcomes Research Interdisciplinary Working Group . Stroke 2006;37:1583-633.

The Canadian Cooperative Study Group A randomized trial of aspirin and sulfinpyrazone in threatened stroke . N Engl J Med 1978;299:53-9.

Antithrombotic Trialists’ Collaboration Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients. BMJ 2002;324:71-86.

CAPRIE Steering Committee A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE) . Lancet 1996;348:1329-39.

Diener HC , Bogousslavsky J. , Brass LM , et al. Aspirin and clopidogrel compad with clopidogrel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): randomised, double-blind, placebo-controlled trial. Lancet 2004;364:331-7.

Diener HC , Cunha L. , Forbes C. , et al. European Stroke Prevention Study: 2: dipyridamole and acetylsalicylic acid in the secondary prevention of stroke. J Neurol Sci 1996;143:1-13.

Sacco RL , Diener HC , Yusuf S. , et al. Aspirin and extended-release dipyridamole versus clopidogrel for recurrent stroke. N Engl J Med 2008;359:1238-51.

Mohr JP , Thompson JL , Lazar RM , et al. A comparison of warfarin and aspirin for the prevention of recurrent ischemic stroke. N Engl J Med 2001;345:1444-51.

Halkes PH , van Gijn J. , Kappelle LJ , et al. Medium intensity oral anticoagulants versus aspirin after cerebral ischaemia of arterial origin (ESPRIT): a randomised controlled trial. Lancet Neurol 2007;6: 115-24.

Risk factors for stroke and efficacy of antithrombotic therapy in atrial fibrillation: analysis of pooled data from five randomized controlled trials. Arch Intern Med 1994;154:1449-57.

Woessner R. , Grauer M. , Bianchi O. , et al. Treatment with anticoagulants in cerebral events (TRACE). Thromb Haemost 2004;91:690-3.

The Publications Committee for the Trial of ORG 10172 in Acute Stroke Treatment (TOAST) Investigators Low molecular weight heparinoid, ORG 10172 (danaparoid), and outcome after acute ischemic stroke: a randomized controlled trial. JAMA 1998;279:1265-72.

Barnett HJ , Taylor DW , Eliasziw M. , et al. , North American Symptomatic Carotid Endarterectomy Trial Collaborators. Benefit of carotid endarterectomy in patients with symptomatic moderate or severe stenosis. N Engl J Med 1998;339:1415-25.

Randomised trial of endarterectomy for recently symptomatic carotid stenosis: final results of the MRC European Carotid Surgery Trial (ECST). Lancet 1998;351:1379-87.

National Institute of Neurological Disorders and Stroke Stroke and Trauma Division North American Symptomatic Carotid Endarterectomy Trial (NASCET) Investigators. Clinical alert: benefit of carotid endarterectomy for patients with high-grade stenosis of the internal carotid artery. Stroke 1991;22:816-7.

Rothwell PM , Slattery J. , Warlow CP A systematic review of the risks of stroke and death due to endarterectomy for symptomatic carotid stenosis. Stroke 1996;27:260-5.

Brott TG , Hobson RW , Howard G. , et al. Stenting versus endarterectomy for treatment of carotid-artery stenosis. N Engl J Med 2010;363:11-23.

Hobson RW , Weiss DG , Fields WS , et al. , The Veterans Affairs Cooperative Study Group. Efficacy of carotid endarterectomy for asymptomatic carotid stenosis. N Engl J Med 1993;328:221-7.

Executive Committee for the Asymptomatic Carotid Atherosclerosis Study Endarterectomy for asymptomatic carotid artery stenosis. JAMA 1995;273:1421-8.

Gray WA , Hopkins LN , Yadav S. , et al. Protected carotid stenting in high-surgical-risk patients: the ARCHeR results. J Vasc Surg 2006;44:258-68.

Katzen BT , Criado FJ , Ramee SR , et al. Carotid artery stenting with emboli protection surveillance study: thirty-day results of the CASES-PMS study. Catheter Cardiovasc Interv 2007;70:316-23.

Rothwell PM , Goldstein LB Carotid endarterectomy for asymptomatic carotid stenosis: asymptomatic carotid surgery trial. Stroke 2004;35:2425-7.

Eckstein HH , Ringleb P. , Allenberg JR , et al. Results of the Stent-Protected Angioplasty versus Carotid Endarterectomy (SPACE) study to treat symptomatic stenoses at 2 years: a multinational, prospective, randomised trial. Lancet Neurol 2008;7:893-902.

Chiam PT , Roubin GS , Panagopoulos G. , et al. One-year clinical outcomes, midterm survival, and predictors of mortality after carotid stenting in elderly patients. Circulation 2009;119:2343-8.

Roubin GS , New G. , Iyer SS , et al. Immediate and late clinical outcomes of carotid artery stenting in patients with symptomatic and asymptomatic carotid artery stenosis: a 5-year prospective analysis. Circulation 2001;103:532-7.

Zahn R. , Ischinger T. , Hochadel M. , et al. Carotid artery stenting in octogenarians: results from the ALKK Carotid Artery Stent (CAS) Registry. Eur Heart J 2007;28:370-5.

Ederle J. , Dobson J. , Featherstone RL , et al. Carotid artery stenting compared with endarterectomy in patients with symptomatic carotid stenosis (International Carotid Stenting Study): an interim analysis of a randomised controlled trial. Lancet 2010;375:985-97.

Gurm HS , Yadav JS , Fayad P. , et al. Long-term results of carotid stenting versus endarterectomy in high-risk patients. N Engl J Med 2008;358:1572-9.

Yadav JS , Wholey MH , Kuntz RE , et al. Protected carotid-artery stenting versus endarterectomy in high-risk patients. N Engl J Med 2004;351:1493-501.

Yadav JS , Sneed D. , Ouriel K. , et al. Durability of carotid stenting for the prevention of stroke: 3-year follow-up of the SAPPHIRE trial and the US Carotid Feasibility. Circulation 2005;112:416. Abstract

Gray WA , Yadav JS , Verta P. , et al. The CAPTURE registry: results of carotid stenting with embolic protection in the post approval setting. Catheter Cardiovasc Interv 2007;69:341-8.

Harrod-Kim P. , Kadkhodayan Y. , Derdeyn CP , et al. Outcomes of carotid angioplasty and stenting for radiation-associated stenosis. AJNR Am J Neuroradiol 2005;26:1781-8.

Rothwell PM , Eliasziw M. , Gutnikov SA , et al. Endarterectomy for symptomatic carotid stenosis in relation to clinical subgroups and timing of surgery. Lancet 2004;363:915-24.

Bates ER , Babb JD , Casey DE Jr. et al. Accf/Scai/Svmb/Sir/ Asitn 2007 clinical expert consensus document on carotid stenting: a report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents (ACCF/ SCAI/SVMB/SIR/ASITN Clinical Expert Consensus Document Committee on Carotid Stenting). J Am Coll Cardiol 2007;49:126-70.

Safian RD , Bacharach JM , Ansel GM , et al. Carotid stenting with a new system for distal embolic protection and stenting in high-risk patients: the carotid revascularization with ev3 arterial technology evolution (CREATE) feasibility trial. Catheter Cardiovasc Interv 2004 ;63:1-6.

White CJ , Iyer SS , Hopkins LN , et al. Carotid stenting with distal protection in high surgical risk patients: the BEACH trial 30 day results. Catheter Cardiovasc Interv 2006;67:503-12.

Barnett HJ Carotid endarterectomy. Lancet 2004 ;363:1486-7.

Taylor DW , Barnett HJ , Haynes RB , et al., ASA and Carotid Endarterectomy (ACE) Trial Collaborators. Low-dose and high-dose acetylsalicylic acid for patients undergoing carotid endarterectomy: a randomised controlled trial. Lancet 1999 ;353:2179-84.

Bhatt DL , Fox KA , Hacke W. , et al. Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events. N Engl J Med 2006 ;354:1706-17.

AbuRahma AF , Robinson PA , Saiedy S. , et al. Prospective randomized trial of bilateral carotid endarterectomies: primary closure versus patching. Stroke 1999 ;30:1185-9.

Bond R. , Rerkasem K. , AbuRahma AF , et al. Patch angioplasty versus primary closure for carotid endarterectomy . Cochrane Database Syst Rev 2004;CD000160

Lamuraglia GM , Stoner MC , Brewster DC , et al. Determinants of carotid endarterectomy anatomic durability: effects of serum lipids and lipid-lowering drugs. J Vasc Surg 2005;41:762-8.

Roth SM , Back MR , Bandyk DF , et al. A rational algorithm for duplex scan surveillance after carotid endarterectomy. J Vasc Surg 1999;30:453-60.

Garg N. , Karagiorgos N. , Pisimisis GT , et al. Cerebral protection devices reduce periprocedural strokes during carotid angioplasty and stenting: a systematic review of the current literature . J Endovasc Ther 2009;16:412-27.

Mas JL , Chatellier G. , Beyssen B. , et al. Endarterectomy versus stenting in patients with symptomatic severe carotid stenosis. N Engl J Med 2006 ;355:1660-71.

Ginsberg HN , Kris-Etherton P. , Dennis B. , et al. Effects of reducing dietary saturated fatty acids on plasma lipids and lipoproteins in healthy subjects: the DELTA Study, protocol 1. Arterioscler Thromb Vasc Biol 1998;18:441-9.

Antiplatelet Trialists’ Collaboration Collaborative overview of randomised trials of antiplatelet therapy-I: prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients. BMJ 1994;308:81-106.

Berguer R. , Morasch MD , Kline RA , et al. Cervical reconstruction of the supra-aortic trunks: a 16-year experience. J Vasc Surg 1999;29:239-46.

Moore WS , Malone JM , Goldstone J. Extrathoracic repair of branch occlusions of the aortic arch. Am J Surg 1976;132:249-57.

Modarai B. , Ali T. , Dourado R. , et al. Comparison of extra-anatomic bypass grafting with angioplasty for atherosclerotic disease of the supra-aortic trunks. Br J Surg 2004;91:1453-7.

Cho L. , Mukherjee D. Basic cerebral anatomy for the carotid interventionalist: the intracranial and extracranial vessels. Catheter Cardiovasc Interv 2006;68:104-11.

Layton KF , Kallmes DF , Cloft HJ , et al. Bovine aortic arch variant in humans: clarification of a common misnomer. AJNR Am J Neuroradiol 2006;27:1541-2.

Wolf PA , Clagett GP , Easton JD , et al. Preventing ischemic stroke in patients with prior stroke and transient ischemic attack: a statement for healthcare professionals from the Stroke Council of the American Heart Association. Stroke 1999;30:1991-4.

Centers for Disease Control and Prevention Prevalence of disabilities and associated health conditions among adults-United States, 1999. MMWR Morb Mortal Wkly Rep 2001;50:120-5.

Pickett CA , Jackson JL , Hemann BA , et al. Carotid bruits as a prognostic indicator of cardiovascular death and myocardial infarction: a meta-analysis. Lancet 2008;371:1587-94.

Wiebers DO , Whisnant JP , Sandok BA , et al. Prospective comparison of a cohort with asymptomatic carotid bruit and a population-based cohort without carotid bruit. Stroke 1990;21:984-8.

Norris JW , Zhu CZ , Bornstein NM , et al. Vascular risks of asymptomatic carotid stenosis. Stroke 1991;22:1485-90.

Kuller LH , Arnold AM , Psaty BM , et al. 10-year follow-up of subclinical cardiovascular disease and risk of coronary heart disease in the Cardiovascular Health Study. Arch Intern Med 2006;166:71-8.

Arnold AM , Psaty BM , Kuller LH , et al. Incidence of cardiovascular disease in older Americans: the Cardiovascular Health Study. J Am Geriatr Soc 2005;53:211-8.

ICAVL standards for accreditation in noninvasive vascular testing: part II: vascular laboratory operations. extracranial cerebrovascular testing. http://www.icavl.org/icavl/pdfs/extracranial2007.pdf . Accessed August 29, 2008

ICAVL standards for accreditation in noninvasive vascular testing . http://www.icavl.org/icavl/apply/standards.htm

Young B. , Moore WS , Robertson JT , et al. An analysis of perioperative surgical mortality and morbidity in the asymptomatic carotid atherosclerosis study. Asymptomatic Carotid Artheriosclerosis Study. Stroke 1996;27:2216-24.

Halliday AW , Thomas D. , Mansfield A. , et al. The Asymptomatic Carotid Surgery Trial (ACST): rationale and design. Steering Committee. Eur J Vasc Surg 1994;8:703-10.

North American Symptomatic Carotid Endarterectomy Trial Collaborators Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. N Engl J Med 1991;325:445-53.

Hertzer NR , Flanagan RA Jr. , Beven EG , et al. Surgical versus non-operative treatment of asymptomatic carotid stenosis. 290 patients documented by intravenous angiography. Ann Surg 1986;204: 163-71.

Spence JD , Coates V. , Li H. , et al. Effects of intensive medical therapy on microemboli and cardiovascular risk in asymptomatic carotid stenosis. Arch Neurol 2010;67:180-6.

Marquardt L. , Geraghty OC , Mehta Z. , et al. Low risk of ipsilateral stroke in patients with asymptomatic carotid stenosis on best medical treatment: a prospective, population-based study. Stroke 2010;41: e11-7.

Abbott AL , Chambers BR , Stork JL , et al. Embolic signals and prediction of ipsilateral stroke or transient ischemic attack in asymptomatic carotid stenosis: a multicenter prospective cohort study. Stroke 2005;36:1128-33.

Goessens BM , Visseren FL , Kappelle LJ , et al. Asymptomatic carotid artery stenosis and the risk of new vascular events in patients with manifest arterial disease: the SMART study. Stroke 2007;38:1470-5.

Mayberg MR , Wilson SE , Yatsu F. , et al. , Veterans Affairs Cooperative Studies Program 309 Trialist Group. Carotid endarterectomy and prevention of cerebral ischemia in symptomatic carotid stenosis. JAMA 1991;266:3289-94.

Halliday A. , Mansfield A. , Marro J. , et al. Prevention of disabling and fatal strokes by successful carotid endarterectomy in patients without recent neurological symptoms: randomised controlled trial. Lancet 2004;363:1491-502.

Fisher M. , Paganini-Hill A. , Martin A. , et al. Carotid plaque pathology: thrombosis, ulceration, and stroke pathogenesis. Stroke 2005; 36:253-7.

Lal BK , Hobson RW , Pappas PJ , et al. Pixel distribution analysis of B-mode ultrasound scan images predicts histologic features of atherosclerotic carotid plaques. J Vasc Surg 2002;35:1210-7.

Redgrave JN , Coutts SB , Schulz UG , et al. Systematic review of associations between the presence of acute ischemic lesions on diffusion-weighted imaging and clinical predictors of early stroke risk after transient ischemic attack . Stroke 2007;38:1482-8.

Adams HP Jr. , Adams RJ , Brott T. , et al. Guidelines for the early management of patients with ischemic stroke: a scientific statement from the Stroke Council of the American Stroke Association. Stroke 2003;34:1056-83.

Williams JE , Rosamond WD , Morris DL Stroke symptom attribution and time to emergency department arrival: the delay in accessing stroke healthcare study. Acad Emerg Med 2000;7:93-6.

Lisabeth LD , Ireland JK , Risser JM , et al. Stroke risk after transient ischemic attack in a population-based setting. Stroke 2004;35: 1842-6.

Kleindorfer D. , Panagos P. , Pancioli A. , et al. Incidence and short-term prognosis of transient ischemic attack in a population-based study . Stroke 2005;36:720-3.

Lovett JK , Dennis MS , Sandercock PA , et al. Very early risk of stroke after a first transient ischemic attack . Stroke 2003;34:e138-40.

Johnston SC , Easton JD Are patients with acutely recovered cerebral ischemia more unstable?. Stroke 2003;34:2446-50.

Fisher M. Stroke and TIA: epidemiology, risk factors, and the need for early intervention . Am J Manag Care 2008;14:S204-11.

Heyman A. , Wilkinson WE , Hurwitz BJ , et al. Risk of ischemic heart disease in patients with TIA. Neurology 1984;34:626-30.

Dennis M. , Bamford J. , Sandercock P. , et al. Prognosis of transient ischemic attacks in the Oxfordshire Community Stroke Project. Stroke 1990;21:848-53.

Whisnant JP Clinical epidemiology in transient cerebral ischemic attacks (TIA) in the anterior and posterior circulation. Sundt TM , editor. Occlusive Cerebrovascular Disease: Diagnosis and Surgical Management 1987;Philadelphia, Pa: W.B. Saunders Co, 60-5.

Naylor AR Occam’s razor: intervene early to prevent more strokes!. J Vasc Surg 2008;48:1053-9.

Gautier JC Amaurosis fugax. N Engl J Med 1993;329:426-8.

Benavente O. , Eliasziw M. , Streifler JY , et al. Prognosis after transient monocular blindness associated with carotid-artery stenosis . N Engl J Med 2001;345:1084-90.

Gaul JJ , Marks SJ , Weinberger J. Visual disturbance and carotid artery disease: 500 symptomatic patients studied by non-invasive carotid artery testing including B-mode ultrasonography . Stroke 1986;17:393-8.

Gallego CJ , Herrera M. , Navarro M. Ophthalmological manifestations of cerebrovascular disease [in Spanish]. An Sist Sanit Navar 2008;31 Suppl3:111-26

Grant EG , Benson CB , Moneta GL , et al. Carotid artery stenosis: gray-scale and Doppler US diagnosis-Society of Radiologists in Ultrasound Consensus Conference. Radiology 2003;229:340-6.

Grant EG , Duerinckx AJ , El Saden SM , et al. Ability to use duplex US to quantify internal carotid arterial stenoses: fact or fiction?. Radiology 2000 ;214:247-52.

Long A. , Lepoutre A. , Corbillon E. , et al. Critical review of non- or minimally invasive methods (duplex ultrasonography, MR- and CT-angiography) for evaluating stenosis of the proximal internal carotid artery. Eur J Vasc Endovasc Surg 2002;24:43-52.

Cowper SE , Kuo PH , Bucala R. Nephrogenic systemic fibrosis and gadolinium exposure: association and lessons for idiopathic fibrosing disorders. Arthritis Rheum 2007;56:3173-5.

Chen CJ , Lee TH , Hsu HL , et al. Multi-slice CT angiography in diagnosing total versus near occlusions of the internal carotid artery: comparison with catheter angiography. Stroke 2004;35:83-5.

Osborn AG Diagnostic Cerebral Angiography. 2nd edition. Philadelphia, Pa: Lippincott Williams & Wilkins ; 1999.

Eisenberg RL , Bank WO , Hedgcock MW Neurologic complications of angiography in patients with critical stenosis of the carotid artery. Neurology 1980;30:892-5.

Earnest F. , Forbes G. , Sandok BA , et al. Complications of cerebral angiography: prospective assessmegsnt of risk. AJR Am J Roentgenol 1984;142:247-53.

Dion JE , Gates PC , Fox AJ , et al. Clinical events following neuroangiography: a prospective study . Stroke 1987;18:997-1004.

Grzyska U. , Freitag J. , Zeumer H. Selective cerebral intraarterial DSA: complication rate and control of risk factors. Neuroradiology 1990;32:296-9.

Hankey GJ , Warlow CP , Sellar RJ Cerebral angiographic risk in mild cerebrovascular disease. Stroke 1990;21:209-22.

Hankey GJ , Warlow CP , Molyneux AJ Complications of cerebral angiography for patients with mild carotid territory ischaemia being considered for carotid endarterectomy. J Neurol Neurosurg Psychiatry 1990;53:542-8.

Davies KN , Humphrey PR Complications of cerebral angiography in patients with symptomatic carotid territory ischaemia screened by carotid ultrasound. J Neurol Neurosurg Psychiatry 1993;56: 967-72.

Leonardi M. , Cenni P. , Simonetti L. , et al. Retrospective study of complications arising during cerebral and spinal diagnostic angiography from 1998 to 2003 . Interv Neuroradiol 2005 ;11:213-21.

MacMahon S. , Peto R. , Cutler J. , et al. Blood pressure, stroke, and coronary heart disease. part 1: prolonged differences in blood pressure: prospective observational studies corrected for the regression dilution bias. Lancet 1990;335:765-74.

Rodgers A. , MacMahon S. , Gamble G. , et al. Blood pressure and risk of stroke in patients with cerebrovascular disease: the United Kingdom Transient Ischaemic Attack Collaborative Group. BMJ 1996;313:147

Lewington S. , Clarke R. , Qizilbash N. , et al. Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet 2002;360:1903-13.

Heiss G. , Sharrett AR , Barnes R. , et al. Carotid atherosclerosis measured by B-mode ultrasound in populations: associations with cardiovascular risk factors in the ARIC study. Am J Epidemiol 1991;134:250-6.

Howard G. , Manolio TA , Burke GL , et al., The Atherosclerosis Risk in Communities (ARIC) and Cardiovascular Health Study (CHS) Investigators Does the association of risk factors and atherosclerosis change with age?. An analysis of the combined ARIC and CHS cohorts. Stroke 1997;28:1693-701.

Wilson PW , Hoeg JM , D’Agostino RB , et al. Cumulative effects of high cholesterol levels, high blood pressure, and cigarette smoking on carotid stenosis. N Engl J Med 1997;337:516-22.

Psaty BM , Arnold AM , Olson J. , et al. Association between levels of blood pressure and measures of subclinical disease. Multi-Ethnic Study of Atherosclerosis. Am J Hypertens 2006;19:1110-7.

Tell GS , Rutan GH , Kronmal RA , et al. , Cardiovascular Health Study (CHS) Collaborative Research Group. Correlates of blood pressure in community-dwelling older adults: the Cardiovascular Health Study. Hypertension 1994;23:59-67.

Crouse JR , Toole JF , McKinney WM , et al. Risk factors for extracranial carotid artery atherosclerosis . Stroke 1987;18:990-6.

Yusuf S. , Sleight P. , Pogue J. , et al. Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients: the Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med 2000;342:145-53.

Rohr J. , Kittner S. , Feeser B. , et al. Traditional risk factors and ischemic stroke in young adults: the Baltimore-Washington Cooperative Young Stroke Study. Arch Neurol 1996;53:603-7.

Howard G. , Wagenknecht LE , Cai J. , et al. Cigarette smoking and other risk factors for silent cerebral infarction in the general population. Stroke 1998;29:913-7.

Lu M. , Ye W. , Adami HO , et al. Stroke incidence in women under 60 years of age related to alcohol intake and smoking habit. Cerebrovasc Dis 2008;25:517-25.

Wasserman BA , Sharrett AR , Lai S. , et al. Risk factor associations with the presence of a lipid core in carotid plaque of asymptomatic individuals using high-resolution MRI: the Multi-Ethnic Study of Atherosclerosis (MESA). Stroke 2008;39:329-35.

Briel M. , Studer M. , Glass TR , et al. Effects of statins on stroke prevention in patients with and without coronary heart disease: a meta-analysis of randomized controlled trials . Am J Med 2004;117:596-606.

MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial. Lancet 2002;360:7-22.

Manson JE , Colditz GA , Stampfer MJ , et al. A prospective study of maturity-onset diabetes mellitus and risk of coronary heart disease and stroke in women. Arch Intern Med 1991;151:1141-7.

Karapanayiotides T. , Piechowski-Jozwiak B. , van Melle G. , et al. Stroke patterns, etiology, and prognosis in patients with diabetes mellitus. Neurology 2004;62:1558-62.

Folsom AR , Rasmussen ML , Chambless LE , et al. Prospective associations of fasting insulin, body fat distribution, and diabetes with risk of ischemic stroke: the Atherosclerosis Risk in Communities (ARIC) Study Investigators. Diabetes Care 1999;22: 1077-83.

Laakso M. Benefits of strict glucose and blood pressure control in type 2 diabetes: lessons from the UK Prospective Diabetes Study. Circulation 1999;99:461-2.

Nathan DM , Cleary PA , Backlund JY , et al. Intensive diabetes treatment and cardiovascular disease in patients with type 1 diabetes. N Engl J Med 2005;353:2643-53.

UK-TIA Study Group United Kingdom transient ischaemic attack (UK-TIA) aspirin trial: interim results. Br Med J (Clin Res Ed) 1988;296:316-20.

Keech A. , Simes RJ , Barter P. , et al. Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial. Lancet 2005;366:1849-61.

Keech A. , Simes J. , Barter P. , et al. Correction to the FIELD study report. Lancet 2006;368:1415.

McNeill AM , Rosamond WD , Girman CJ , et al. Prevalence of coronary heart disease and carotid arterial thickening in patients with the metabolic syndrome (the ARIC Study). Am J Cardiol 2004;94:1249-54.

Montalcini T. , Gorgone G. , Federico D. , et al. Association of LDL cholesterol with carotid atherosclerosis in menopausal women affected by the metabolic syndrome . Nutr Metab Cardiovasc Dis 2005;15:368-72.

Kawamoto R. , Ohtsuka N. , Ninomiya D. , et al. Carotid atherosclerosis in normal-weight metabolic syndrome. Intern Med 2007;46:1771-7.

Rundek T. , White H. , Boden-Albala B. , et al. The metabolic syndrome and subclinical carotid atherosclerosis: the Northern Manhattan Study. J Cardiometab Syndr 2007;2:24-9.

Montalcini T. , Gorgone G. , Gazzaruso C. , et al. Carotid atherosclerosis associated to metabolic syndrome but not BMI in healthy menopausal women. Diabetes Res Clin Pract 2007;76:378-82.

Kawamoto R. , Tomita H. , Inoue A. , et al. Metabolic syndrome may be a risk factor for early carotid atherosclerosis in women but not in men. J Atheroscler Thromb 2007;14:36-43.

Ishizaka N. , Ishizaka Y. , Toda E. , et al. Association between cigarette smoking, metabolic syndrome, and carotid arteriosclerosis in Japanese individuals. Atherosclerosis 2005;181:381-8.

Wallenfeldt K. , Hulthe J. , Fagerberg B. The metabolic syndrome in middle-aged men according to different definitions and related changes in carotid artery intima-media thickness (IMT) during 3 years of follow-up . J Intern Med 2005;258:28-37.

Iglseder B. , Cip P. , Malaimare L. , et al. The metabolic syndrome is a stronger risk factor for early carotid atherosclerosis in women than in men. Stroke 2005;36:1212-7.

Scuteri A. , Najjar SS , Muller DC , et al. Metabolic syndrome amplifies the age-associated increases in vascular thickness and stiffness . J Am Coll Cardiol 2004;43:1388-95.

Kawamoto R. , Tomita H. , Oka Y. , et al. Metabolic syndrome amplifies the LDL-cholesterol associated increases in carotid atherosclerosis . Intern Med 2005;44:1232-8.

Kawamoto R. , Tomita H. , Oka Y. , et al. Metabolic syndrome and carotid atherosclerosis: role of elevated blood pressure. J Atheroscler Thromb 2005;12:268-75.

Irace C. , Cortese C. , Fiaschi E. , et al. Components of the metabolic syndrome and carotid atherosclerosis: role of elevated blood pressure. Hypertension 2005;45:597-601.

Teramura M. , Emoto M. , Araki T. , et al. Clinical impact of metabolic syndrome by modified NCEP-ATP III criteria on carotid atherosclerosis in Japanese adults . J Atheroscler Thromb 2007;14:172-8.

Empana JP , Zureik M. , Gariepy J. , et al. The metabolic syndrome and the carotid artery structure in noninstitutionalized elderly subjects: the three-city study. Stroke 2007;38:893-9.

Winter Y. , Rohrmann S. , Linseisen J. , et al. Contribution of obesity and abdominal fat mass to risk of stroke and transient ischemic attacks. Stroke 2008 ;39:3145-51.

Goldstein LB , Adams R. , Becker K. , et al. Primary prevention of ischemic stroke: a statement for healthcare professionals from the Stroke Council of the American Heart Association. Circulation 2001;103:163-82.

North American Symptomatic Carotid Endarterectomy Trial: methods, patient characteristics, and progress. Stroke 1991;22:711-20.

Goldstein LB , Hasselblad V. , Matchar DB , et al. Comparison and meta-analysis of randomized trials of endarterectomy for symptomatic carotid artery stenosis. Neurology 1995;45:1965-70.

Rothwell PM , Eliasziw M. , Gutnikov SA , et al. Analysis of pooled data from the randomised controlled trials of endarterectomy for symptomatic carotid stenosis. Lancet 2003 ;361:107-16.

Rothwell PM , Gutnikov SA , Warlow CP Reanalysis of the final results of the European Carotid Surgery Trial. Stroke 2003;34: 514-23.

Mas JL , Trinquart L. , Leys D. , et al. Endarterectomy Versus Angioplasty in Patients with Symptomatic Severe Carotid Stenosis (EVA-3S) trial: results up to 4 years from a randomised, multicentre trial. Lancet Neurol 2008;7:885-92.

Bonati LH , Jongen LM , Haller S. , et al. New ischaemic brain lesions on MRI after stenting or endarterectomy for symptomatic carotid stenosis: a substudy of the International Carotid Stenting Study (ICSS). Lancet Neurol 2010;9:353-62.

Suissa S. Calculation of number needed to treat. N Engl J Med 2009;361:424-5.

Ferguson GG , Eliasziw M. , Barr HW , et al. The North American Symptomatic Carotid Endarterectomy Trial: surgical results in 1415 patients . Stroke 1999;30:1751-8.

Bond R. , Rerkasem K. , Cuffe R. , et al. A systematic review of the associations between age and sex and the operative risks of carotid endarterectomy. Cerebrovasc Dis 2005;20:69-77.

Bond R. , Rerkasem K. , Shearman CP , et al. Time trends in the published risks of stroke and death due to endarterectomy for symptomatic carotid stenosis. Cerebrovasc Dis 2004;18:37-46.

Bond R. , Rerkasem K. , Naylor AR , et al. Systematic review of randomized controlled trials of patch angioplasty versus primary closure and different types of patch materials during carotid endarterectomy. J Vasc Surg 2004;40:1126-35.

Naylor AR , Bolia A. , Abbott RJ , et al. Randomized study of carotid angioplasty and stenting versus carotid endarterectomy: a stopped trial. J Vasc Surg 1998;28:326-34.

Endovascular versus surgical treatment in patients with carotid stenosis in the Carotid and Vertebral Artery Transluminal Angioplasty Study (CAVATAS): a randomised trial. Lancet 2001 ;357:1729-37.

Brooks WH , McClure RR , Jones MR , et al. Carotid angioplasty and stenting versus carotid endarterectomy: randomized trial in a community hospital. J Am Coll Cardiol 2001;38:1589-95.

Ringleb PA , Allenberg J. , Bruckmann H. , et al. 30 day results from the SPACE trial of stent-protected angioplasty versus carotid endarterectomy in symptomatic patients: a randomised non-inferiority trial [published correction appears in Lancet. 2006;368:1238]. Lancet 2006;368:1239-47.

Coward LJ , Featherstone RL , Brown MM Safety and efficacy of endovascular treatment of carotid artery stenosis compared with carotid endarterectomy: a Cochrane systematic review of the randomized evidence. Stroke 2005;36:905-11.

Gurm HS , Nallamothu BK , Yadav J. Safety of carotid artery stenting for symptomatic carotid artery disease: a meta-analysis. Eur Heart J 2008;29:113-9.

Ederle J. , Featherstone RL , Brown MM Percutaneous transluminal angioplasty and stenting for carotid artery stenosis . Cochrane Database Syst Rev 2007 ;CD000515

Cywinski JB , Koch CG , Krajewski LP , et al. Increased risk associated with combined carotid endarterectomy and coronary artery bypass graft surgery: a propensity-matched comparison with isolated coronary artery bypass graft surgery. J Cardiothorac Vasc Anesth 2006;20:796-802.

Stoner MC , Abbott WM , Wong DR , et al. Defining the high-risk patient for carotid endarterectomy: an analysis of the prospective National Surgical Quality Improvement Program database. J Vasc Surg 2006;43:285-95.

Debing E. , Van den Brande P. Does the type, number or combinations of traditional cardiovascular risk factors affect early outcome after carotid endarterectomy?. Eur J Vasc Endovasc Surg 2006;31:622-6.

Coward LJ , Featherstone RL , Brown MM Percutaneous transluminal angioplasty and stenting for carotid artery stenosis . Cochrane Database Syst Rev 2004 ;CD000515

Back MR Commentary: protected carotid stenting in high-surgical-risk patients: the ARCHeR results. Perspect Vasc Surg Endovasc Ther 2006;18:349-51.

Coward LJ , Featherstone RL , Brown MM Percutaneous transluminal angioplasty and stenting for vertebral artery stenosis . Cochrane Database Syst Rev 2005 ;CD000516

Crawley F. , Brown MM Percutaneous transluminal angioplasty and stenting for carotid artery stenosis . Cochrane Database Syst Rev 2000 ;CD000515

Gray WA Endovascular treatment of extra-cranial carotid artery bifurcation disease . Minerva Cardioangiol 2005;53:69-77.

Gray WA A cardiologist in the carotids. J Am Coll Cardiol 2004;43:1602-5.

Illig KA , Zhang R. , Tanski W. , et al. Is the rationale for carotid angioplasty and stenting in patients excluded from NASCET/ACAS or eligible for ARCHeR justified?. J Vasc Surg 2003;37:575-81.

Kasirajan K. What is the latest in inventory for carotid stenting and cerebral protection? . Perspect Vasc Surg Endovasc Ther 2005;17:135-41.

Naylor AR Regarding "protected carotid stenting in high-surgical-risk patients: the ARCHeR results.". J Vasc Surg 2007;45:222-3.

Schonholz CJ , Uflacker R. , Parodi JC , et al. Is there evidence that cerebral protection is beneficial? Clinical data. J Cardiovasc Surg ( Torino) 2006;47:137-41.

Devlin TG , Baxter BW , Feintuch TA , et al. The Merci Retrieval System for acute stroke: the Southeast Regional Stroke Center experience. Neurocrit Care 2007 ;6:11-21.

DeRubertis BG , Chaer RA , Gordon R. , et al. Determining the quantity and character of carotid artery embolic debris by electron microscopy and energy dispersive spectroscopy. J Vasc Surg 2007;45:716-24.

Maleux G. , Demaerel P. , Verbeken E. , et al. Cerebral ischemia after filter-protected carotid artery stenting is common and cannot be predicted by the presence of substantial amount of debris captured by the filter device. AJNR Am J Neuroradiol 2006;27:1830-3.

Reimers B. , Tubler T. , de Donato G. , et al. Endovascular treatment of in-stent restenosis after carotid artery stenting: immediate and midterm results. J Endovasc Ther 2006 ;13:429-35.

Imai K. , Mori T. , Izumoto H. , et al. Successful stenting seven days after atherothrombotic occlusion of the intracranial internal carotid artery. J Endovasc Ther 2006;13:254-9.

Macdonald S. Is there any evidence that cerebral protection is beneficial? Experimental data. J Cardiovasc Surg ( Torino) 2006;47: 127-36.

Quan VH , Huynh R. , Seifert PA , et al. Morphometric analysis of particulate debris extracted by four different embolic protection devices from coronary arteries, aortocoronary saphenous vein conduits, and carotid arteries. Am J Cardiol 2005;95:1415-9.

Sprouse LR , Peeters P. , Bosiers M. The capture of visible debris by distal cerebral protection filters during carotid artery stenting: is it predictable?. J Vasc Surg 2005;41:950-5.

Bush RL , Lin PH , Bianco CC , et al. Reevaluation of temporary transvenous cardiac pacemaker usage during carotid angioplasty and stenting: a safe and valuable adjunct. Vasc Endovascular Surg 2004;38:229-35.

Ohki T. , Veith FJ Critical analysis of distal protection devices. Semin Vasc Surg 2003;16:317-25.

Bosiers M. , Peeters P. , Verbist J. , et al. Belgian experience with FilterWire EX in the prevention of embolic events during carotid stenting . J Endovasc Ther 2003;10:695-701.

Grube E. , Colombo A. , Hauptmann E. , et al. Initial multicenter experience with a novel distal protection filter during carotid artery stent implantation. Catheter Cardiovasc Interv 2003;58:139-46.

Sievert H. , Rabe K. Role of distal protection during carotid stenting . J Interv Cardiol 2002;15:499-504.

Al-Mubarak N. , Colombo A. , Gaines PA , et al. Multicenter evaluation of carotid artery stenting with a filter protection system. J Am Coll Cardiol 2002;39:841-6.

Jaeger H. , Mathias K. , Drescher R. , et al. Clinical results of cerebral protection with a filter device during stent implantation of the carotid artery. Cardiovasc Intervent Radiol 2001;24:249-56.

Tubler T. , Schluter M. , Dirsch O. , et al. Balloon-protected carotid artery stenting: relationship of periprocedural neurological complications with the size of particulate debris. Circulation 2001;104:2791-6.

Parodi JC , La Mura R. , Ferreira LM , et al. Initial evaluation of carotid angioplasty and stenting with three different cerebral protection devices. J Vasc Surg 2000;32:1127-36.

Ohki T. , Roubin GS , Veith FJ , et al. Efficacy of a filter device in the prevention of embolic events during carotid angioplasty and stenting: an ex vivo analysis. J Vasc Surg 1999;30:1034-44.

Kitta Y. , Obata JE , Takano H. , et al. Echolucent carotid plaques predict in-stent restenosis after bare metal stenting in native coronary arteries. Atherosclerosis 2008;197:177-82.

Geary GG The vascular therapist. Heart Lung Circ 2007 ;16:193-9.

Teng ZZ , Ji GY , Chu HJ , et al. Does PGA external stenting reduce compliance mismatch in venous grafts?. Biomed Eng Online 2007; 6:12.

Bosiers M. , de Donato G. , Deloose K. , et al. Are there predictive risk factors for complications after carotid artery stenting? J Cardiovasc Surg (Torino) 2007;48:125-30.

Parodi JC , Schonholz C. , Parodi FE , et al. Initial 200 cases of carotid artery stenting using a reversal-of-flow cerebral protection device. J Cardiovasc Surg ( Torino) 2007;48:117-24.

Peynircioglu B. , Geyik S. , Yavuz K. , et al. Exclusion of atherosclerotic plaque from the circulation using stent-grafts: alternative to carotid stenting with a protection device?. Cardiovasc Intervent Radiol 2007;30:854-60.

Younis GA , Gupta K. , Mortazavi A. , et al. Predictors of carotid stent restenosis. Catheter Cardiovasc Interv 2007;69:673-82.

de Souza JM , Espinosa G. , Santos MM , et al. Bilateral occlusion associated to steal phenomenon of internal carotid and left subclavian arteries: treatment by angioplasty and stenting. Surg Neurol 2007 ;67:298-302.

Chahwan S. , Miller MT , Pigott JP , et al. Carotid artery velocity characteristics after carotid artery angioplasty and stenting. J Vasc Surg 2007;45:523-6.

Kadkhodayan Y. , Moran CJ , Derdeyn CP , et al. Carotid angioplasty and stent placement for restenosis after endarterectomy. Neuroradiology 2007;49:357-64.

de Borst GJ , Ackerstaff RG , De Vries JP , et al. Carotid angioplasty and stenting for postendarterectomy stenosis: long-term follow-up. J Vasc Surg 2007;45:118-23.

Protack CD , Bakken AM , Saad WA , et al. Radiation arteritis: a contraindication to carotid stenting?. J Vasc Surg 2007;45:110-7.

Ali ZA , Alp NJ , Lupton H. , et al. Increased in-stent stenosis in ApoE knockout mice: insights from a novel mouse model of balloon angioplasty and stenting. Arterioscler Thromb Vasc Biol 2007 ;27:833-40.

Park B. , Aiello F. , Dahn M. , et al. Follow-up results of carotid angioplasty with stenting as assessed by duplex ultrasound surveillance. Am J Surg 2006;192:583-8.

Gupta R. , Al-Ali F. , Thomas AJ , et al. Safety, feasibility, and short-term follow-up of drug-eluting stent placement in the intracranial and extracranial circulation. Stroke 2006;37:2562-6.

Hauth EA , Drescher R. , Jansen C. , et al. Complications and follow-up after unprotected carotid artery stenting. Cardiovasc Intervent Radiol 2006 ;29:511-8.

Cao P. , De Rango P. , Verzini F. , et al. Outcome of carotid stenting versus endarterectomy: a case-control study. Stroke 2006;37:1221-6.

Lal BK , Hobson RW Management of carotid restenosis . J Cardiovasc Surg (Torino) 2006;47:153-60.

Halabi M. , Gruberg L. , Pitchersky S. , et al. Carotid artery stenting in surgical high-risk patients. Catheter Cardiovasc Interv 2006;67: 513-8.

Eskandari MK , Longo GM , Matsumura JS , et al. Carotid stenting done exclusively by vascular surgeons: first 175 cases. Ann Surg 2005;242:431-6.

Morrish W. , Grahovac S. , Douen A. , et al. Intracranial hemorrhage after stenting and angioplasty of extracranial carotid stenosis . AJNR Am J Neuroradiol 2000;21:1911-6.

Ho DS , Wang Y. , Chui M. , et al. Epileptic seizures attributed to cerebral hyperperfusion after percutaneous transluminal angioplasty and stenting of the internal carotid artery. Cerebrovasc Dis 2000;10: 374-9.

Buhk JH , Cepek L. , Knauth M. Hyperacute intracerebral hemorrhage complicating carotid stenting should be distinguished from hyperperfusion syndrome. AJNR Am J Neuroradiol 2006;27: 1508-13.

Henry M. , Gopalakrishnan L. , Rajagopal S. , et al. Bilateral carotid angioplasty and stenting. Catheter Cardiovasc Interv 2005;64: 275-82.

Nicosia A. , Leotta E. , Moshiri S. , et al. Carotid artery stenting in the presence of contralateral carotid occlusion: mind the hyperperfusion syndrome! Ital Heart J 2004;5:152-6.

Chen MS , Bhatt DL , Mukherjee D. , et al. Feasibility of simultaneous bilateral carotid artery stenting . Catheter Cardiovasc Interv 2004;61:437-42.

Hartmann M. , Weber R. , Zoubaa S. , et al. Fatal subarachnoid hemorrhage after carotid stenting. J Neuroradiol 2004;31:63-6.

Chuang YM , Wu HM Early recognition of cerebral hyperperfusion syndrome after carotid stenting-a case report. Kaohsiung J Med Sci 2001;17:489-94.

Capoccia L. , Speziale F. , Gazzetti M. , et al. Comparative study on carotid revascularization (endarterectomy vs stenting) using markers of cellular brain injury, neuropsychometric tests, and diffusion-weighted magnetic resonance imaging. J Vasc Surg 2010;51:584-91.

Tedesco MM , Lee JT , Dalman RL , et al. Postprocedural microembolic events following carotid surgery and carotid angioplasty and stenting. J Vasc Surg 2007;46:244-50.

Kwon BJ , Han MH , Kang HS , et al. Protection filter-related events in extracranial carotid artery stenting: a single-center experience. J Endovasc Ther 2006;13:711-22.

Cardaioli P. , Giordan M. , Panfili M. , et al. Complication with an embolic protection device during carotid angioplasty. Catheter Cardiovasc Interv 2004;62:234-6.

Eskandari MK , Najjar SF , Matsumura JS , et al. Technical limitations of carotid filter embolic protection devices. Ann Vasc Surg 2007;21:403-7.

Valibhoy AR , Mwipatayi BP , Sieunarine K. Fracture of a carotid stent: an unexpected complication. J Vasc Surg 2007;45:603-6.

Yallampalli S. , Zhou W. , Lin PH , et al. Delayed deformation of self-expanding stents after carotid artery stenting for postendarterectomy restenoses. J Vasc Surg 2006;44:412-5.

Setacci C. , de Donato G. , Setacci F. , et al. In-stent restenosis after carotid angioplasty and stenting: a challenge for the vascular surgeon . Eur J Vasc Endovasc Surg 2005 ;29:601-7.

Schillinger M. , Exner M. , Sabeti S. , et al. Excessive carotid in-stent neointimal formation predicts late cardiovascular events . J Endovasc Ther 2004;11:229-39.

Rapp JH , Wakil L. , Sawhney R. , et al. Subclinical embolization after carotid artery stenting: new lesions on diffusion-weighted magnetic resonance imaging occur postprocedure . J Vasc Surg 2007;45: 867-72.

Hart JP , Peeters P. , Verbist J. , et al. Do device characteristics impact outcome in carotid artery stenting? . J Vasc Surg 2006;44:725-30.

Powell RJ , Alessi C. , Nolan B. , et al. Comparison of embolization protection device-specific technical difficulties during carotid artery stenting. J Vasc Surg 2006;44:56-61.

Safian RD , Bresnahan JF , Jaff MR , et al. Protected carotid stenting in high-risk patients with severe carotid artery stenosis. J Am Coll Cardiol 2006;47:2384-9.

Hamood H. , Makhoul N. , Hassan A. , et al. Embolic protection: limitations of current technology and novel concepts. Int J Cardiovasc Intervent 2005;7:176-82.

Gruberg L. , Beyar R. Cerebral embolic protection devices and percutaneous carotid artery stenting. Int J Cardiovasc Intervent 2005;7:117-21.

Yadav JS Embolic protection devices: methods, techniques, and data. Tech Vasc Interv Radiol 2004;7:190-3.

Cil BE , Turkbey B. , Canyigit M. , et al. An unusual complication of carotid stenting: spontaneous rectus sheath hematoma and its endovascular management . Diagn Interv Radiol 2007;13:46-8.

Pipinos II , Johanning JM , Pham CN , et al. Transcervical approach with protective flow reversal for carotid angioplasty and stenting . J Endovasc Ther 2005;12:446-53.

Zorger N. , Finkenzeller T. , Lenhart M. , et al. Safety and efficacy of the Perclose suture-mediated closure device following carotid artery stenting under clopidogrel platelet blockade . Eur Radiol 2004;14:719-22.

Gupta A. , Bhatia A. , Ahuja A. , et al. Carotid stenting in patients older than 65 years with inoperable carotid artery disease: a single-center experience. Catheter Cardiovasc Interv 2000;50:1-8.

Schneider LM , Roubin GS Minimal contrast use in carotid stenting: avoiding contrast pitfalls. J Invasive Cardiol 2007;19:37-8.

Wholey MH , Al-Mubarek N. , Wholey MH Updated review of the global carotid artery stent registry. Catheter Cardiovasc Interv 2003;60:259-66.

Theiss W. , Hermanek P. , Mathias K. , et al. Pro-CAS: a prospective registry of carotid angioplasty and stenting . Stroke 2004;35: 2134-9.

Kastrup A. , Groschel K. , Krapf H. , et al. Early outcome of carotid angioplasty and stenting with and without cerebral protection devices: a systematic review of the literature. Stroke 2003;34:813-9.

Barbato JE , Dillavou E. , Horowitz MB , et al. A randomized trial of carotid artery stenting with and without cerebral protection. J Vasc Surg 2008;47:760-5.

Qureshi AI , Kirmani JF , Divani AA , et al. Carotid angioplasty with or without stent placement versus carotid endarterectomy for treatment of carotid stenosis: a meta-analysis. Neurosurgery 2005;56:1171-9.

Brahmanandam S. , Ding EL , Conte MS , et al. Clinical results of carotid artery stenting compared with carotid endarterectomy. J Vasc Surg 2008;47:343-9.

Luebke T. , Aleksic M. , Brunkwall J. Meta-analysis of randomized trials comparing carotid endarterectomy and endovascular treatment. Eur J Vasc Endovasc Surg 2007;34:470-9.

Murad MH , Flynn DN , Elamin MB , et al. Endarterectomy vs stenting for carotid artery stenosis: a systematic review and meta-analysis. J Vasc Surg 2008 ;48:487-93.

Meier P. , Knapp G. , Tamhane U. , et al. Short term and intermediate term comparison of endarterectomy versus stenting for carotid artery stenosis: systematic review and meta-analysis of randomised controlled clinical trials. BMJ 2010;340:c467.

Hobson RW CREST (Carotid Revascularization Endarterectomy versus Stent Trial): background, design, and current status. Semin Vasc Surg 2000;13:139-43.

Hobson RW , Howard VJ , Roubin GS , et al. Carotid artery stenting is associated with increased complications in octogenarians: 30-day stroke and death rates in the CREST lead-in phase . J Vasc Surg 2004;40:1106-11.

Roubin GS , Clark WM , Chakhtoura EY , et al. Low complication rates for carotid artery stenting in the credentialling phase of the carotid revascularization endarterectomy versus stenting trial . Stroke 2006;37:620. Abstract.

Moore WS , Kempczinski RF , Nelson JJ , et al. Recurrent carotid stenosis: results of the Asymptomatic Carotid Atherosclerosis Study. Stroke 1998;29:2018-25.

Matsagas MI , Bali C. , Arnaoutoglou E. , et al. Carotid endarterectomy with bovine pericardium patch angioplasty: mid-term results. Ann Vasc Surg 2006;20:614-9.

Cunningham EJ , Bond R. , Mehta Z. , et al. Long-term durability of carotid endarterectomy for symptomatic stenosis and risk factors for late postoperative stroke. Stroke 2002 ;33:2658-63.

Bond R. , Rerkasem K. , Naylor R. , et al. Patches of different types for carotid patch angioplasty. Cochrane Database Syst Rev 2004;CD000071

Cikrit DF , Larson DM , Sawchuk AP , et al. Discretionary carotid patch angioplasty leads to good results . Am J Surg 2006;192:e46-50.

Cunningham EJ , Bond R. , Mayberg MR , et al. Risk of persistent cranial nerve injury after carotid endarterectomy. J Neurosurg 2004;101:445-8.

Rockman CB , Halm EA , Wang JJ , et al. Primary closure of the carotid artery is associated with poorer outcomes during carotid endarterectomy . J Vasc Surg 2005;42:870-7.

Hansen F. , Lindblad B. , Persson NH , et al. Can recurrent stenosis after carotid endarterectomy be prevented by low-dose acetylsalicylic acid? A double-blind, randomised and placebo-controlled study. Eur J Vasc Surg 1993;7:380-5.

Petrik PV , Gelabert HA , Moore WS , et al. Cigarette smoking accelerates carotid artery intimal hyperplasia in a dose-dependent manner. Stroke 1995;26:1409-14.

Gelabert HA , el- Massry S. , Moore WS Carotid endarterectomy with primary closure does not adversely affect the rate of recurrent stenosis . Arch Surg 1994 ;129:648-54.

Salvian A. , Baker JD , Machleder HI , et al. Cause and noninvasive detection of restenosis after carotid endarterectomy. Am J Surg 1983;146:29-34.

AbuRahma AF , Robinson PA , Saiedy S. , et al. Prospective randomized trial of carotid endarterectomy with primary closure and patch angioplasty with saphenous vein, jugular vein, and polytetrafluoroethylene: long-term follow-up. J Vasc Surg 1998;27:222-32.

Lord RS , Raj TB , Stary DL , et al. Comparison of saphenous vein patch, polytetrafluoroethylene patch, and direct arteriotomy closure after carotid endarterectomy: part I: perioperative results. J Vasc Surg 1989;9:521-9.

Eikelboom BC , Ackerstaff RG , Hoeneveld H. , et al. Benefits of carotid patching: a randomized study. J Vasc Surg 1988;7:240-7.

Curley S. , Edwards WS , Jacob TP Recurrent carotid stenosis after autologous tissue patching. J Vasc Surg 1987;6:350-4.

Awad IA , Little JR Patch angioplasty in carotid endarterectomy: advantages, concerns, and controversies . Stroke 1989;20:417-22.

Bernstein EF , Torem S. , Dilley RB Does carotid restenosis predict an increased risk of late symptoms, stroke, or death?. Ann Surg 1990;212:629-36.

Nicholls SC , Phillips DJ , Bergelin RO , et al. Carotid endarterectomy: relationship of outcome to early restenosis. J Vasc Surg 1985;2:375-81.

O’Donnell TF Jr. , Callow AD , Scott G. , et al. Ultrasound characteristics of recurrent carotid disease: hypothesis explaining the low incidence of symptomatic recurrence . J Vasc Surg 1985;2:26-41.

Zierler RE , Bandyk DF , Thiele BL , et al. Carotid artery stenosis following endarterectomy. Arch Surg 1982;117:1408-15.

Stoney RJ , String ST Recurrent carotid stenosis. Surgery 1976;80:705-10.

Hertzer NR , Beven EG , O’Hara PJ , et al. A prospective study of vein patch angioplasty during carotid endarterectomy: three-year results for 801 patients and 917 operations. Ann Surg 1987;206:628-35.

Hertzer NR , Martinez BD , Benjamin SP , et al. Recurrent stenosis after carotid endarterectomy . Surg Gynecol Obstet 1979;149:360-4.

DeGroote RD , Lynch TG , Jamil Z. , et al. Carotid restenosis: long-term noninvasive follow-up after carotid endarterectomy. Stroke 1987;18:1031-6.

Wehman JC , Hanel RA , Guidot CA , et al. Atherosclerotic occlusive extracranial vertebral artery disease: indications for intervention, endovascular techniques, short-term and long-term results. J Interv Cardiol 2004;17:219-32.

Wityk RJ , Chang HM , Rosengart A. , et al. Proximal extracranial vertebral artery disease in the New England Medical Center Posterior Circulation Registry. Arch Neurol 1998;55:470-8.

Chimowitz MI , Lynn MJ , Howlett-Smith H. , et al. Comparison of warfarin and aspirin for symptomatic intracranial arterial stenosis. N Engl J Med 2005;352:1305-16.

Hornig CR , Lammers C. , Buttner T. , et al. Long-term prognosis of infratentorial transient ischemic attacks and minor strokes. Stroke 1992;23:199-204.

Marquardt L. , Kuker W. , Chandratheva A. , et al. Incidence and prognosis of ≥50% symptomatic vertebral or basilar artery stenosis: prospective population-based study. Brain 2009;132:982-8.

Blacker DJ , Flemming KD , Wijdicks EF Risk of ischemic stroke in patients with symptomatic vertebrobasilar stenosis undergoing surgical procedures. Stroke 2003;34:2659-63.

Savitz SI , Caplan LR Vertebrobasilar disease. N Engl J Med 2005 ;352:2618-26.

Caplan LR Atherosclerotic vertebral artery disease in the neck. Curr Treat Options Cardiovasc Med 2003;5:251-6.

Canyigit M. , Arat A. , Cil BE , et al. Management of vertebral stenosis complicated by presence of acute thrombus. Cardiovasc Intervent Radiol 2007;30:317-20.

Eckert B. Acute vertebrobasilar occlusion: current treatment strategies. Neurol Res 2005; 27 Suppl1:S36-41

Kasner SE , Lynn MJ , Chimowitz MI , et al. Warfarin vs aspirin for symptomatic intracranial stenosis: subgroup analyses from WASID. Neurology 2006;67:1275-8.

Benesch CG , Chimowitz MI , WASID Investigators Best treatment for intracranial arterial stenosis? 50 years of uncertainty. Neurology 2000;55:465-6.

Grotta JC , Norris JW , Kamm B. , et al. Prevention of stroke with ticlopidine: who benefits most?. Neurology 1992;42:111-5.

Sivenius J. , Riekkinen PJ , Smets P. , et al. The European Stroke Prevention Study (ESPS): results by arterial distribution. Ann Neurol 1991;29:596-600.

Berguer R. , Flynn LM , Kline RA , et al. Surgical reconstruction of the extracranial vertebral artery: management and outcome . J Vasc Surg 2000;31:9-18.

Berguer R. Suboccipital approach to the distal vertebral artery. J Vasc Surg 1999;30:344-9.

Berguer R. , Morasch MD , Kline RA A review of 100 consecutive reconstructions of the distal vertebral artery for embolic and hemodynamic disease. J Vasc Surg 1998;27:852-9.

Spetzler RF , Hadley MN , Martin NA , et al. Vertebrobasilar insufficiency: part 1: microsurgical treatment of extracranial vertebrobasilar disease. J Neurosurg 1987;66:648-61.

Hopkins LN , Martin NA , Hadley MN , et al. Vertebrobasilar insufficiency: part 2: microsurgical treatment of intracranial vertebrobasilar disease. J Neurosurg 1987;66:662-74.

Hopkins LN , Budny JL Complications of intracranial bypass for vertebrobasilar insufficiency. J Neurosurg 1989;70:207-11.

Hopkins LN , Budny JL , Castellani D. Extracranial-intracranial arterial bypass and basilar artery ligation in the treatment of giant basilar artery aneurysms . Neurosurgery 1983;13:189-94.

Hopkins LN , Budny JL , Spetzler RF Revascularization of the rostral brain stem . Neurosurgery 1982 ;10:364-9.

Berguer R. , Bauer RB Vertebral artery reconstruction: a successful technique in selected patients. Ann Surg 1981 ;193:441-7.

Berguer R. , Bauer RB Vertebrobasilar arterial occlusive diesase: medical and surgical management . New York, NY: Raven Press; 1984.

Roon AJ , Ehrenfeld WK , Cooke PB , et al. Vertebral artery reconstruction. Am J Surg 1979;138:29-36.

Malone JM , Moore WS , Hamilton R. , et al. Combined carotid-vertebral vascular disease: a new surgical approach. Arch Surg 1980;115:783-5.

Caplan L. , Tettenborn B. Embolism in the posterior circulation. In: Berguer R , Caplan L , editors. Vertebrobailar Arterial Disease. St. Louis, Mo : Quality Medical, 1992.

Thevenet A. , Ruotolo C. Surgical repair of vertebral artery stenoses . J Cardiovasc Surg (Torino ) 1984;25:101-10.

Edwards WH , Mulherin JL Jr. The surgical reconstruction of the proximal subclavian and vertebral artery. J Vasc Surg 1985;2:634-42.

Diaz FG , Ausman JI , de los Reyes RA , et al. Surgical reconstruction of the proximal vertebral artery. J Neurosurg 1984;61:874-81.

Imparato AM , Riles TS , Kim GE Cervical vertebral angioplasty for brain stem ischemia. Surgery 1981;90:842-52.

Eberhardt O. , Naegele T. , Raygrotzki S. , et al. Stenting of vertebrobasilar arteries in symptomatic atherosclerotic disease and acute occlusion: case series and review of the literature. J Vasc Surg 2006 ;43:1145-54.

Law MM , Colburn MD , Moore WS , et al. Carotid-subclavian bypass for brachiocephalic occlusive disease: choice of conduit and long-term follow-up. Stroke 1995;26:1565-71.

AbuRahma AF , Bates MC , Stone PA , et al. Angioplasty and stenting versus carotid-subclavian bypass for the treatment of isolated subclavian artery disease. J Endovasc Ther 2007;14:698-704.

De Vries JP , Jager LC , van den Berg JC , et al. Durability of percutaneous transluminal angioplasty for obstructive lesions of proximal subclavian artery: long-term results. J Vasc Surg 2005;41:19-23.

Sullivan TM , Gray BH , Bacharach JM , et al. Angioplasty and primary stenting of the subclavian, innominate, and common carotid arteries in 83 patients. J Vasc Surg 1998;28:1059-65.

Brountzos EN , Petersen B. , Binkert C. , et al. Primary stenting of subclavian and innominate artery occlusive disease: a single center’s experience. Cardiovasc Intervent Radiol 2004;27:616-23.

Hadjipetrou P. , Cox S. , Piemonte T. , et al. Percutaneous revascularization of atherosclerotic obstruction of aortic arch vessels. J Am Coll Cardiol 1999;33:1238-45.

Whitbread T. , Cleveland TJ , Beard JD , et al. A combined approach to the treatment of proximal arterial occlusions of the upper limb with endovascular stents . Eur J Vasc Endovasc Surg 1998;15:29-35.

Rodriguez-Lopez JA , Werner A. , Martinez R. , et al. Stenting for atherosclerotic occlusive disease of the subclavian artery. Ann Vasc Surg 1999;13:254-60.

Van Noord BA , Lin AH , Cavendish JJ Rates of symptom reoccurrence after endovascular therapy in subclavian artery stenosis and prevalence of subclavian artery stenosis prior to coronary artery bypass grafting . Vasc Health Risk Manag 2007;3:759-62.

Peterson BG , Resnick SA , Morasch MD , et al. Aortic arch vessel stenting: a single-center experience using cerebral protection. Arch Surg 2006;141:560-3.

Filippo F. , Francesco M. , Francesco R. , et al. Percutaneous angioplasty and stenting of left subclavian artery lesions for the treatment of patients with concomitant vertebral and coronary subclavian steal syndrome . Cardiovasc Intervent Radiol 2006;29:348-53.

van Hattum ES , De Vries JP , Lalezari F. , et al. Angioplasty with or without stent placement in the brachiocephalic artery: feasible and durable?. A retrospective cohort study. J Vasc Interv Radiol 2007;18:1088-93.

Naylor AR , Cuffe RL , Rothwell PM , et al. A systematic review of outcomes following staged and synchronous carotid endarterectomy and coronary artery bypass. Eur J Vasc Endovasc Surg 2003;25:380-9.

Moussa I. , Rundek T. , Mohr JP Asymptomatic Carotid Artery Stenosis: Risk Stratification and Management . London, UK: Informa Healthcare Publishers; 2006.

Brener B. , Hermans H. , Eisenbud D. , et al. The management of patients requiring coronary bypass and carotid endarterectomy. In: Moore W S , editor. Surgery for Cerebrovascular Disease. 2nd edition. Philadelphia, Pa: W.B. Saunders, 1996:278-9.

Ricotta JJ , Wall LP , Blackstone E. The influence of concurrent carotid endarterectomy on coronary bypass: a case-controlled study . J Vasc Surg 2005;41:397-401.

Byrne J. , Darling RC III , Roddy SP , et al. Combined carotid endarterectomy and coronary artery bypass grafting in patients with asymptomatic high-grade stenoses: an analysis of 758 procedures . J Vasc Surg 2006;44:67-72.

Dubinsky RM , Lai SM Mortality from combined carotid endarterectomy and coronary artery bypass surgery in the US. Neurology 2007;68:195-7.

Kougias P. , Kappa JR , Sewell DH , et al. Simultaneous carotid endarterectomy and coronary artery bypass grafting: results in specific patient groups. Ann Vasc Surg 2007;21:408-14.

Van der Heyden J. , Suttorp MJ , Bal ET , et al. Staged carotid angioplasty and stenting followed by cardiac surgery in patients with severe asymptomatic carotid artery stenosis: early and long-term results. Circulation 2007;116:2036-42.

Timaran CH , Rosero EB , Smith ST , et al. Trends and outcomes of concurrent carotid revascularization and coronary bypass. J Vasc Surg 2008;48:355-60.

Slovut DP , Olin JW Fibromuscular dysplasia. N Engl J Med 2004 ;350:1862-71.

Olin JW Recognizing and managing fibromuscular dysplasia. Cleve Clin J Med 2007;74:273-82.

Zhou W. , Bush RL , Lin PL , et al. Fibromuscular dysplasia of the carotid artery. J Am Coll Surg 2005;200:807.

Dayes LA , Gardiner N. The neurological implications of fibromuscular dysplasia. Mt Sinai J Med 2005;72:418-20.

Stahlfeld KR , Means JR , Didomenico P. Carotid artery fibromuscular dysplasia. Am J Surg 2007;193:71-2.

Ballotta E. , Thiene G. , Baracchini C. , et al. Surgical vs medical treatment for isolated internal carotid artery elongation with coiling or kinking in symptomatic patients: a prospective randomized clinical study . J Vasc Surg 2005;42:838-46.

Assadian A. , Senekowitsch C. , Assadian O. , et al. Combined open and endovascular stent grafting of internal carotid artery fibromuscular dysplasia: long term results . Eur J Vasc Endovasc Surg 2005;29: 345-9.

Finsterer J. , Strassegger J. , Haymerle A. , et al. Bilateral stenting of symptomatic and asymptomatic internal carotid artery stenosis due to fibromuscular dysplasia . J Neurol Neurosurg Psychiatry 2000;69:683-6.

DiLuna ML , Bydon M. , Gunel M. , et al. Neurological picture: complications from cervical intra-arterial heroin injection. J Neurol Neurosurg Psychiatry 2007;78:1198.

Zaidat OO , Frank J. Vertebral artery dissection with amphetamine abuse. J Stroke Cerebrovasc Dis 2001;10:27-9.

Schievink WI Spontaneous dissection of the carotid and vertebral arteries. N Engl J Med 2001;344:898-906.

Kawchuk GN , Jhangri GS , Hurwitz EL , et al. The relation between the spatial distribution of vertebral artery compromise and exposure to cervical manipulation. J Neurol 2008;255:371-7.

Cohen JE , Gomori JM , Umansky F. Endovascular management of symptomatic vertebral artery dissection achieved using stent angioplasty and emboli protection device. Neurol Res 2003;25:418-22.

Shah Q. , Messe SR Cervicocranial arterial dissection. Curr Treat Options Neurol 2007;9:55-62.

Turowski B. , Hanggi D. , Siebler M. Intracranial bilateral vertebral artery dissection during anticoagulation after cerebral venous and sinus thrombosis (CSVT). Acta Neurochir ( Wien) 2007;149: 793-7.

Lyrer P. , Engelter S. Antithrombotic drugs for carotid artery dissection. Stroke 2004;35:613-4.