Hounsfield GNComputerised transverse axial scanning (tomography): Part 1. Description of system. Br J Radiol1973; 46: 1016-22.
2.
Baker Jr HL, Campbell JK, Houser OW, Reese DF, Sheedy PF, Holman CBComputer assisted tomography of the head. An early evaluation. Mayo Clin Proc1974; 49: 17-27.
3.
Jacoby R., Levy R.Computed tomography in the elderly: 2. senile dementia: diagnosis and functional impairment. Br J Psychiatry1980; 136: 256-69.
4.
Colgan J., Naguib M., Levy R.Computed tomographic density numbers. A comparative study of patients with senile dementia and normal elderly controls. Br J Psychiatry1986; 149: 716-19.
5.
Pinching AJNeurological aspects of the acquired immune deficiency syndrome. J R Coll Phys Lond1988; 22: 136-39.
6.
Ell PJ, Costa DC, Harrison Mgj.Imaging cerebral damage in HIV infection. Lancet1987; ii: 569-70.
7.
Hinshaw WS, Bottomley PA, Holland GNRadiographic thin-section image of the human wrist by nuclear magnetic resonance . Nature1977; 279: 722-23.
Nakada T., Kwee IL, Griffey BV, Griffey RHF-19 MR imaging of glucose metabolism in the rabbit. Radiology1988; 168: 823-25.
10.
Sokoloff L. , Reivich M., Kennedy C. et al. The [14C]deoxyglucose method for the measurement of local cerebral glucose utilisation: theory, procedure, and normal values in the conscious and anesthetized albino rat. J Neurochem1977; 28: 897-916.
11.
Ingvar DH, Lassen NAQuantitative determination of regional cerebral blood flow in man. Lancet1961; ii: 806-807.
12.
Veall N., Mallett BLThe two-compartment model using 133Xe inhalation and external counting. Acta Neurol Scand1965; 14 (suppl): 83-84.
13.
Reivich M., Kuhl D., Wolf A. et al. The [18F]fluoro-deoxyglucose method for the measurement of local cerebral glucose utilization in man. Circ Res1979; 44: 127-37.
14.
Kety SS, Schmidt CFThe determination of cerebral blood flow in man by the use of nitrous oxide in low concentrations. Am J Physiol1945; 143: 53-66.
15.
Kety SS, Schmidt CFThe nitrous oxide method for the quantitative determination of cerebral blood flow in man: theory, procedure and normal values. J Clin Invest1948; 27: 476-83.
16.
Kety SS, Woodford RB, Harmel MH, Freyhan FA, Appel KE, Schmidt CFCerebral blood flow and metabolism in schizophrenia. The effects of barbiturate semi-narcosis, insulin coma and electroshock. Am J Psychiatry1948; 104: 765-70.
17.
Kety SSThe measurement of regional circulation by local clearance of radioactive sodium. Am Heart J1949; 38: 321-28.
18.
Lassen NA, Lindbjerg IF, Munck O.Measurement of blood flow through skeletal muscle by intramuscular injection of 133Xe. Lancet1964; i: 686-89.
19.
Hoedt-Rasmussen L., Sveinsdottir E., Lassen NARegional cerebral blood flow in man determined by intra-arterial injection of radioactive inert gas. Circ Res1966; 18: 237-47.
20.
Obrist WD, Thompson HK, King CH, Wang HSDetermination of regional cerebral blood flow by inhalation of 133-xenon. Circ Res1967; 20: 124-35.
21.
Rosenstein J., Suzuki M., Symon L., Redmond S.Clinical use of a portable bedside cerebral blood flow machine in the management of aneurysmal subarachnoid hemorrhage . Neurosurgery1984; 15: 519-25.
22.
Agnoli A., Prencipe M., Priori Aam, Bozzao I., Fieschi C.Measurements of rCBF by intravenous injection of 133-xenon. In: Brock M, Fieschi C, Ingvar DH, Lassen NA, Schurmann K eds, Cerebral blood flow, Berlin, Heidelberg, New York : Springer Verlag, 1969: 31-34.
23.
Obrist WD, Wang HSComparison of 133-xenon inhalation and IV injection in regional CBF studies . In: Meyer JS, Lechner H, Reivich M, Ott EO, Arabinar A eds, Cerebral vascular disease, Amsterdam: Excerpta Medica, 1981: 140-44.
24.
Naritomi H. , Meyer JS, Sakai F., Yamaguchi F., Shaw T.Effects of advancing age on regional cerebral blood flow. Arch Neurol1979; 36: 410-16.
25.
Melamed E., Lavy S., Bentin S., Cooper G., Rinot Y.Reduction in regional cerebral blood flow during normal aging in man. Stroke1980; 11: 31-35.
Muizelaar JP , Lutz HA, Becker DPEffect of manitol on ICP and CBF and correlation with pressure auto-regulation in severely head-injured patients. J Neurosurg1984; 61: 700-706.
28.
Lavy S., Melamed E., Bentin S., Cooper G., Rinot Y.Bihemispheric decreases of regional cerebral blood flow in dementia: correlation with age-matched normal controls. Ann Neurol1978; 4: 445-50.
29.
Gur RE, Skolnick BE, Gur RC et al. Brain function in psychiatric disorders: II regional cerebral blood flow in medicated unipolar depressives. Arch Gen Psychiatry1984; 41: 695-99.
30.
Kanno I., Lassen NATwo methods for calculating regional cerebral blood flow from emission computed tomography of inert gas concentrations. J Comput Assist Tomogr1979; 3: 71-76.
31.
Lassen NA, Sveinsdottir E., Kanno I., Stokely EM, Rommer P.A fast moving, single photon emission tomograph for regional cerebral blood flow studies in man. J Comput Assist Tomogr1978; 2: 661-62.
32.
Kety SSThe theory and applications of the exchange of inert gas at the lungs and tissues. Pharmacol Rev1951; 3: 1-41.
33.
Celsis P., Goldman T., Henriksen L., Lassen NAA method for calculating regional cerebral blood flow from emission computed tomography of inert gas concentrations. J Comput Assist Tomogr1981; 5: 641-45.
34.
Winchell HS , Baldwin RM, Lin THDevelopment of I-123 labelled amines for brain studies: localization of I-123 iodophenylalkylamines in rat brain. J Nucl Med1980; 21: 940-46.
35.
Winchell HS , Horst WD, Braun L., Oldendorf WH, Hattner R., Parker H.N-isopropyl [123I]-p-iodoamphetamine: single-pass brain uptake and washout; binding to brain synaptosomes; and localization in dog and monkey brain. J Nucl Med1980; 21: 947-52.
36.
Kung HF, Blau M.Regional intracellular pH shift: a proposed new mechanism for radiopharmaceutical uptake in brain and other tissues. J Nucl Med1980; 21: 147-52.
37.
Kung FH, Tramposch KM, Blau M.A new brain perfusion imaging agent: [I-123]HIPDM:N,N,N'-trimethyl-N'-[2-hydroxy-3-methyl-5-iodobenzyl]-1,3-propanediamine . J Nucl Med1984; 24: 66-72.
38.
Holman BL, Hill TC, Lee Rgl, Zimmerman RE, Moore SC, Royal HDBrain imaging with radiolabelled amines. Nuclear Medicine Annual1983: 131-65.
39.
Royal HD, Hill TC, Holman BLClinical brain imaging with isopropyliodoamphetamine and SPECT. Semin Nucl Med1985; 15: 357-76.
40.
Loberg MDRadiotracers for cerebral functional imaging - a new class. J Nucl Med1980; 21: 183-85.
41.
Berl S., Takagaki G., Clarke DD, Waelsch H.Metabolic compartments in vivo. Ammonia and glutamic acid metabolism in brain and liver. J Biol Chem1962; 237: 2562-69.
42.
Ibister WH, Schofield PF, Torrance HBMeasurement of the solubility of xenon-133 in blood and human brain. Phys Med Biol1965; 10: 243-50.
43.
Oldendorf WHNeed for new radiopharmaceuticals. J Nucl Med1978; 19: 1182.
44.
Kung HF, Molnar M., Billings J., Wicks R., Blau M.Synthesis and biodistribution of neutral lipid-soluble Tc-99m complexes that cross the blood-brain barrier. J Nucl Med1984; 25: 326-32.
45.
Volkert WA, McKenzie EH, Hoffman TJ, Troutner DE, Holmes RAThe behaviour of neutral amine oxime chelates labelled with Tc at tracer level . Int J Nucl Med Biol1984; 11: 243-46.
46.
Troutner DE , Volkert WA, Hoffman TJ, Holmes RAA neutral lipophilic complex of Tc-99m with a multidentate amine oxime. Int J Appl Radiat Isot1984; 35: 467-70.
Holmes RA, Chaplin SB, Royston KG et al. Cerebral uptake and retention of 99Tcmhexamethylpropyleneamine oxime (99Tcm-HM-PAO). Nucl Med Commun1985 ; 6: 443-47.
49.
Ell PJ, Cullum I., Costa DC et al. A new regional cerebral blood flow mapping with 99mTc-labelled compound. Lancet1985; ii: 50-51.
50.
Ell PJ, Hocknell Jml, Jarritt PH et al. A 99Tcm-labelled radiotracer for the investigation of cerebral vascular disease. Nucl Med Commun1985; 6: 437-41.
51.
Costa DC, Ell PJ, Nowotnik DPHM-PAO: a new technitium-99m labelled agent for brain SPECT. J Nucl Med Allied Sciences1985; 29: 337- 38.
52.
Nowotnik DP, Canning LR, Cumming SA et al. Tc-99m-HM-PAO: a new radiopharmaceutical for imaging regional cerebral blood flow. In: Nicolini, Bandoli MG, Mazzi U eds, Technetium in Chemistry and Nuclear Medicine 2, New York: Raven Press, 1986: 187-92.
53.
Pickett RDThe biodistribution of technetium 99m-HMPAO in rats. Amersham International, 1985.
54.
Pickett RDCalculation of radiation doses to subjects following intravenous injection of Tc-99m-HM-PAO. Amersham International, 1985.
55.
Costa DC, Jones BE, Steiner TJ et al. Relative 99mTc-HM-PAO and 113Sn-microspheres distribution in dog brain. Nuklearmedizin1987; (suppl 23): 498-500.
56.
Altman DG, Bland JMMeasurement in medicine: the analysis of method comparison studies. The Statistician1983; 32: 307-17.
57.
Costa DC, Lui D., Sinha AK, Jarritt PH, Ell PJIntracellular localisation of 99Tcm-d,l-HMPAO and 201Tl-DDC in rat brain. Nucl Med Commun1989.
58.
Costa DC, Hubank M., Sinha A., Lui D., Ell PJInfluence of time, temperature, sodium-potassium pump inhibition and glutathione on the 99Tcm-HMPAO uptake by cultured astrocytes. Eur J Nucl Med1989; 15: 584.
59.
Costa DC, Lui D., Ell PJTc-99m-HMPAO uptake in rat brain: sensitivity to physiological and pharmacological intervention 'in vivo'. Nucl Med1987; 26: 146-47.
60.
Choksey MS, Costa DC, Iannotti I., Ell PJ, Crockard HA99mTc-HMPAO SPET and cerebral blood flow, a study of CO2 reactivity . Nucl Med Commun1989; 10: 609-18.
61.
Costa DC, Davies Ptg, Jones BE, Steiner TJ, Jewkes RF, Clifford Rose F.99Tcm-HMPAO studies in patients with migraine, tension and cluster headache . Nucl Med Commun1988; 9: 196-97.
62.
Costa DC, Stibe Cma, Lees AJ et al. Tc-99m-HMPAO rCBF/SPET in Parkinsonians with the 'ON-OFF' syndrome: preliminary results. Nuklearmedizin1988; (suppl 24): 344-47.
63.
Costa DC, Ell PJFocal temporal lobe epilepsy: oblique reconstruction and slice re-orientation improves HMPAO/SPET analysis. Nucl Med Commun1989; 10: 231.
64.
Costa DC, Ell PJ, Burns A., Philpot M., Levy R.CBF tomograms with [99mTc]-HM-PAO in patients with dementia (Alzheimer type and HIV) and Parkinson's disease - initial results. J Cereb Blood Flow Metab1988; 8: S109-15.
65.
Burns A., Philpot M., Costa DC, Ell PJ, Levy R.The investigation of Alzheimer's disease with single photon emission tomography . J Neurol Neurosurg Psychiatry1989; 52: 248-53.
66.
Costa DC, Philpot M., Burns A., Ell PJ, Levy R.Clinical presentation vs. quantitative HMPAO/SPET in the follow-up of patients with dementia of Alzheimer type (DAT). Nucl Med1990; (suppl 26): 352-54.
67.
Costa DC, Ell PJ99mTc-HMPAO washout in prognosis of stroke. Lancet1989; i: 213-14.
68.
Costa DCA study of the first 99Tcm-labelled radiopharmaceutical for the investigation of cerebral flow in man (Thesis). London: University of London, 1989.
69.
Ell PJ, Hocknell Jml, Costa DC et al. 99mTChexamethyl-propyleneamineoxime (99mTc-HM-PAO): a breakthrough in radionuclide CBF tomography. Nuklearmedizin1986; (suppl 22): 179-81.
70.
Costa DC, Ell PJ, Cullum ID, Jarritt PHThe in vivo distribution of 99Tcm-HM-PAO in normal man. Nucl Med Commun1986; 7: 647-58.
71.
Sharp PF, Smith FW, Gemmell HG et al. Technetium- 99m HM-PAO stereoisomers as potential agents for imaging regional cerebral blood flow: human volunteer studies. J Nucl Med1986; 27: 171-77.
72.
El-Gazzar AH , Sadek S., Bahar R., Rageb A., Omar YT, Abdel-Dayem HMUptake of Tc-99m-hexamethylpropyleneamineoxime (Tc-99m-HM-PAO) by healthy and diseased lungs. Nucl Med1987; 26: 149-90.