Filippi M , Campi A , Martinelli Vet al.Transitional progressive multiple sclerosis: MRI and MTI findings . Acta Neurol Scand1995; 92: 178-182 .
2.
van Buchem MA , McGowan JC , Kolson DL , Polansky M , Grossman RI.Quantitative volumetric magnetization transfer analysis in multiple sclerosis: estimation of macroscopic and microscopic disease burden . MRM1996;36: 632-636 .
3.
Horsfield MA , Lai M , Wegg SL , Barker GJ , Tofts PS , Turner R , Rudge P , Miller DH.Apparent diffusion coefficients in benign and secondary progressive multiple sclerosis by nuclear magnetic resonance . MRM1996;36: 393-400 .
4.
Christiansen P , Gideon P , Thomsen C , Stuggaard M , Henriksen 0 , Larsson HBW.Increased water self-diffusion in chronic plaques and in apparently normal white matter in patients with multiple sclerosis . Acta Neurol Scand1993;87: 195-199 .
5.
Morrissey SP , Stodal H , Zettl Uet al.In vivo MRI and its histological correlates in acute adoptive transfer experimental allergic encephalomyelitis: quantification of inflammation and oedema . Brain1996:119: 239-248 .
6.
Newcombe J , Hawkins CP , Henderson CL , et al.Histopathology of multiple sclerosis lesions detected by magnetic resonance imaging in unfixed postmortem central nervous system tissue . Brain1991;114: 1013-1023 .
7.
Bruck W , Bitsch A , Kolenda H , Bruck Y , Stiefel M , Lassmann H.Inflammatory central nervous system demyelination: correlation of magnetic resonance imaging findings with lesion pathology . Ann Neurol1997;42: 783-793 .
8.
Trapp BD , Peterson J , Ransohoff RM , Rudick R , Mork S , Bo L.Axonal transection in the lesions of multiple sclerosis . N Engl J Med1998:338: 278-285 .
9.
Goodkin DE , Rooney W , et al.PD, T1, Gadolinium (Gd+) intensities, T2 and MTRs are chronically diffusely abnormal in MS brain and on monthly MRI scans are related to the appearance of new Gd+ lesions in normal appearing white matter (NAWM) . Neurology;1998;50: A191-A191 .
10.
Filippi M , Rocca MA , Martino G , Horsfield MA , Como G.Magnetization transfer changes in the normal appearing white matter precede the appearance of enhancing lesions in patients with multiple sclerosis . Ann Neurol1998;43: 809-814 .
11.
Grossman RI.Magnetic resonance imaging: current status and strategies for improving MS clinical trial design. In; Multiple Sclerosis: Advances in clinical trial design, treatment and future perspectives. Eds; Goodkin DE. , Rudick RA.Springer-Verlag, London1996:161-186
12.
Allen IVMcKeown SR.A histological, histochemical and bio-chemical study of the macroscopically normal white matter in multiple sclerosis . J Neurol Sci1979;41: 81-91 .
13.
McFarland HF , Frank JA , Albert PS , et al.Using gadolinium-enhanced magnetic resonance imaging lesions to monitor disease activity in multiple sclerosis . Ann Neurol1992;32: 758-766 .
14.
Panitch HS.Influence of infection on exacerbations of multiple sclerosis . Ann Neurol1994;36: S25-S28 .
15.
Mohr DC , Russo D , Reiss M , Chang J , Goodkin DE.Relationship of stress, psychological distress, and disease activity in multiple sclerosis patients . Ann Neurol1997;42: 443-443 .
16.
Franklin GM , Nelson LM , Heaton RKBurks JS , Thompson DS.Stress and its relationships to acute exacerbation in multiple sclerosis. J Neurol Rehabil1988;2: 398-403 .
17.
Sharief MK , Hentges R.Association between TNF alpha and disease progression in patients with multiple sclerosis . N Engl J Med1991;325: 467-472 .
18.
Martino G , Filippi M , Martinelli Vet al.Interferon-gamma induced increases in intracellular calcium in T lymphocytes from patients with multiple sclerosis precede clinical exacerbations and detection of active lesions on MRI . J Neurol Neurosurg and Psychiatry1997;63: 339-345 .
19.
Trojano M , Avolio C , Simone ILet al.Soluble intercellular adhesion molecule-1 in serum and cerebrospinal fluid of clinically active relapsing-remitting multiple sclerosis: correlation with Gd-DTPA magnetic resonance imaging-enhancement and cerebrospinal fluid findings . Neurology1996;47: 1535-1541 .
20.
Anthony DC , Ferguson B , Matysak MK , Miller KM , Esiri MM.Perry VH.Differential matrix metalloproteinase expression in cases of multiple sclerosis and stroke . Neuropathology and Applied Neurobiology1997;23: 406-415 .
21.
Wolansky LJ , Bardini JA , Cook SD , Zimmer AE , Sheffet A , Lee HJ.Triple-dose versus single-dose gadoteridol in multiple sclerosis patients . J Neuroimag1994;4: 141-145 .