Intravenous immunoglobulin treatment in Multiple Sclerosis and experimental autoimmune encephalomyelitis - the Israeli Experience

Zweiman B. (1989) Theoretical mechanisms by which immunoglobulin therapy might benefit myasthenia gravis . Clin iImmunol Immunopathol 53: 583-591.

Sandor et al. (1990) CD4+ murine T cell clones that express high levels of immunoglobulin binding belong to the interleukin-4-producing T helper cell type 2 subset . J Exp Med 171: 2171- 2176.

Sandor et al. (1992) In vitro and in vivo activation of murine γ/6 T cells induce the expression of IgA, IgM, and IgG Fc receptors . J Immunol 148: 2363-2369.

Maynier M. , Cosso B. , Brochier J. , Clot J. ( 1987) Identification of class II HLA alloantibodies in placenta-eluted gamma globulin used for treating rheumatoid arthritis . Arthr Rheumat 30: 375-381.

Wurster U. , Haas J. ( 1994) Passage of intravenous immunoglobulin and interaction with the CNS . J Neurol Neurosurg Psychiatry 57(suppl): 21-35.

Rodiguez M. , Lennon VA (1990) Immunoglobulins promote remyelination in the central nervous system . Ann Neurol 27: 12 -17.

Rodriguez M. (1991) Immunoglobulins stimulate central nervous system remyelination: electron microscopic and morphometric analysis of proliferating cells . Lab Invest 64: 358-370.

Lemire JM , Weigle WO (1986) Myelin basic protein-specific T cell clones and experimental allergic encephalomyelitis . Pathol Immunopathol Res 5: 248-252.

Mokhatarian VF , McFarlin DE , Raine CS (1984) Adoptive transfer of myelin basic protein-synthesized T cells produce chronic relapsing demyelinating disease in mice . Nature 309: 356-358.

Achiron A. et al. (1994) Intravenous immunoglobulin treatment of experimental T-cell mediated autoimmune diseases: Up-regulation of T cell proliferation and downregulation of TNF-α secretion . J Clin Invest 93: 600-605.

Achiron A. et al. (1994) Intravenous gammaglobulin treatment in multiple sclerosis and experimental autoimmune diseases: delineation of usage and mode of action . J Neurol Neurosurg Psychiatry 57(suppl): 57-61.

Rotherfelder U. , Neu I. , Pelka R. (1982) Therapy for multiple sclerosis with immunoglobulin G . Munch Med Wochenschr 124: 74-78.

Schuller E. , Govaerts A. (1983) First results of immunotherapy with immunoglobulin G in multiple sclerosis patients . Eur Neurol 22: 205 - 212.

Soukop W. , Tschabitscher H. (1986) Gamma globulin therapy in multiple sclerosis. Theoretical considerations and initial clinical experience with 7S immunoglobulins in MS therapy . Wien Med Wochenschr 136: 477-480.

Achiron et al. (1992) Open controlled therapeutic trial of high-dose intravenous immunoglobulins in relapsing-remitting multiple sclerosis . Arch Neurol 49: 1233-1236.

Kurtzke JF (1983) Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS) . Neurology 33: 1444 -1452.

Achiron A. et al. (1996) Intravenous immunoglobulin in multiple sclerosis: clinical and neuroradiologic results and implications for possible mechanisms of action . Clin Exp Immunol 104(suppl 1): 67-70.

Korn-Lubetzki I. , Kahana E. , Cooper G. , Abramsky O. (1984) Activity of multiple sclerosis during pregnancy and puerperium . Ann Neurol 16: 228-231.

Birk K. et al. (1990) The clinical course of multiple sclerosis during pregnancy and the puerperium . Arch Neurol 47: 738 - 742.

Achiron A. et al. (1996) Intravenous immunoglobulin treatment in the prevention of childbirth associated acute exacerbations in multiple sclerosis-A pilot study . J Neurol 243: 25 - 28.

Achiron A. et al. (1996) Intravenous immunoglobulin in multiple sclerosis: A multicenter, double-blind, placebo-controlled trial . Neurology 46(suppl): A405 -406.