Remyelination in multiple sclerosis: a challenge for therapy

Barbellion Wnp. (1919) The Journal of a Disappointed Man. London: Chatto and Windus: pp 312.

Lassmann H. (1983) Comparative neuropathology of chronic experimental allergic encephaloymelitis and multiple sclerosis. New York: Springer Verlag: pp 37-72.

Prineas J. , Connell F. (1979) Remyelination in multiple sclerosis. Annals of Neurology 5: 22 - 31.

Prineas JW et al. (1993) Multiple sclerosis: remyelination of nascent lesions. Annals of Neurology 33: 137 - 151.

Babinski J. (1885) Étude anatomique et clinique sur la sclerose en plaques. Paris, Masson: pp 95.

Charcot JM. (1880) Leçons sur les Maladies du Système Nerveux faites a la Salpetriére. A Delahaye and E Lecrosnier; Progrès Médicale, Paris. 3rd edition: pp 1-495 and 1 - 504. Translated into English by George Sigerson as: Lectures on the Diseases of the Nervous System delivered at the Salpetriére. The New Sydenham Society. London 1877: pp 157 - 222.

Dawson JD (1916) The Histology of Disseminated Sclerosis. Transactions of the Royal Society of Edinburgh 50: 517 - 740.

Cruveilhier J. (1835 - 42) Anatomie pathologique du corps humain; descriptions avec figures lithographiées et coloriées; des diverses alterations morbides dont le corps humain est susceptible. Paris: JB Bailliere (not paginated).

Carswell R. (1838) Pathological anatomy; Illustrations of the Elementary Forms of Disease. London: Longman, Orme, Brown, Green and Longman (not paginated).

Marburg O. (1906) Die sogennante "akute multiple sklerose". Jahrbuch fur Psychiatre und Neurologie 27: 211 - 312.

Rindfleisch E. (1863) Histologisches detail zu der grauen degeneration von gehirn und ruckenmark. Archives of Pathological Anatomy and Physiology 26: 474 - 483.

Bunge MB , Bunge RP , Ris H. (1961) Ultrastructural study of remyelination in an experimental lesion in adult cat spinal cord. The Journal of Biophysical and Biochemical Cytology 10: 67 - 94.

Perier O. , Grégoire A. (1965) Electron microscopic features of multiple sclerosis . Brain 88: 937 - 952.

Gledhill RF , Harrison BM , McDonald WI (1973) Pattern of remyelination in the CNS. Nature 244: 443 - 444.

Smith KJ , Blakemore WF , McDonald WI (1979) Central remyelination restores secure conduction . Nature 280: 395 - 396.

Smith KJ , Blakemore WF , McDonald WI (1981) The restoration of conduction by central remyelination . Brain 104: 383 - 404.

Robertson WF (1899) On a new method of obtaining a black reaction in certain tissue elements of the central nervous system (platinum method). Scottish Medical and Surgical Journal 4: 23 - 30.

Cajal SR (1913) Contribucion al conocmiento de la neuroglia del cerebra humano. Trabajos de Laboratorio de Investigaciones Biologicas 11: 255 - 315.

del Rio-Hortega P. (1921) Estudios sobre la neuroglia. La glia de escasas radiciones (oligodendroglia). Boletin de la Real Sociedad Espanola de la Historia Natural.

del Rio-Hortega P. (1928) Tercera aportacia al conocimiento morfologico e interpretacion funcional de la oligodendroglia. Memoria de la Real Sociedad Espanola de la Historia Natural 14: 5 - 122.

Raff MC , Miller RH , Noble M. (1983) A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on culture medium. Nature 303: 390 - 396.

ffrench Constant C. , Raff MC (1986) Proliferating bipotential glial progenitor cells in adult rat optic nerve. Nature 319: 499 - 502.

Wolswijk G. , Noble M. (1992) Co-operation between PDGF and FGF converts slowly dividing 0 - 2A (adult) progenitor cells to rapidly dividing cells with characteristics of 0 - 2A (perinatal) progenitor cells . Journal of Cell Biology 118: 889 - 900.

Kennedy Pge , Fok-Seang J. (1986) Studies on the development, antigenic phenotype, and function of human glial cells in tissue culture. Brain 109: 1261- 1277.

Weidenheim KM , Epshteyn I. , Rashbaum WK , Lyman WD (1994) Patterns of glial development in the human foetal spinal cord during the late first and second trimester . Journal of Neurocytology 23 : 343 - 353.

Yu WP , Collarini EJ , Pringle NP , Richardson WD (1994) Embryonic expression of myelin genes: Evidence for a focal source of oligodendrocyte precursors in the ventricular zone of the neural tube. Neuron 12: 1353- 1362.

Aloisi F. et al. (1992) Developmental appearance, antigenic profile and proliferation of glial cells of the human embryonic spinal cord. Glia 5: 171 - 181.

Satoh J. , Kim SU (1994) Proliferation and differentiation of fetal human oligodendrocytes in vitro. Journal of Neuroscience Research 39: 260 - 272.

Rivkin MJ et al. (1995) Oligodendroglial development in human fetal cerebrum. Annals of Neurology 38: 92 - 101.

Armstrong RC , Dorn HH , Kufta CV et al. (1992) Pre-oligodendrocytes from adult human CNS. Journal of Neuroscience 12: 1538 - 1547.

Scolding NJ et al. (1995) A proliferative adult human oligodendrocyte progenitor. NeuroReport 6: 441 - 445.

Scolding N. , Shaw C. , Rayner P. , Compston Das. The adult human oligodendrocyte lineage: existence of progenitors in situ and formation of myelin in vitro. (submitted).

Gogate N. et al. (1994) Plasticity in the adult human oligodendrocyte lineage. Journal of Neuroscience 14: 4571 - 4587.

Whittemore SR , Sanon HR , Wood PM (1993) Concurrent isolation and characterisation of oligodendrocytes, microglia and astrocytes from adult human spinal cord. International Journal of Developmental Neuroscience 11: 755 - 764.

Zajicek JP , Compston Das. (1994) Myelination in vitro of dorsal root ganglia by glial progenitor cells. Brain 117: 1333 - 1350.

Jones C. , Landon D. , McDonald WI (1980) Remyelination during optic nerve compression. Journal of the Neurological Sciences 46: 239-243.

Blakemore WF , Crang AJ , Curtis R. (1986) The interaction of Schwann cells with CNS axons in regions containing normal astrocytes. Acta Neuropathologica ( Berlin) 71: 295-300.

Carroll WM , Jennings AR , Mastaglia FL (1990) The origin of remyelinating oligodendrocytes in antiserum-mediated demyelinative optic neuropathy. Brain 113: 953 - 973.

Carroll WM , Jennings AR (1994) Early recruitment of oligodendrocyte precursors in CNS demyelination. Brain 117: 563-578.

Small RK , Riddle P. , Noble M. (1987) Evidence for migration of oligodendrocyte-type 2 astrocyte progenitor cells into the developing rat optic nerve. Nature 328: 155-157.

Duncan ID et al. (1988) Transplantation of oligodendrocytes and Schwann cells into the spinal cord of the myelin-deficient rat. Journal of Neurocytology 17: 351-360.

Halliday AM , Mushin J. , McDonald WI (1972) Delayed visual evoked response in optic neuritis. Lancet i: 982- 985 .

Halliday AM , McDonald WI , Mushin J. (1973) Visual evoked response in diagnosis of multiple sclerosis. British Medical Journal 4: 661-664.

Halliday AM et al. (1976) The pattern-evoked potential in compression of the anterior visual pathways. Brain 99: 357-374.

Kriss A. , Francis DA , Cuendet F. et al. (1988) Recovery after optic neuritis in childhood . Journal of Neurology Neurosurgery and Psychiatry 51: 1253-1258.

Miller DH et al. (1988) Magnetic resonance imaging of the optic nerve in optic neuritis. Neurology 38: 175 - 179.

Baron-van Evercooren A. (1997) Demyelination in the non-human primate CNS: a model to study the potential of transplantation in myelin repair . Multiple Sclerosis 3(Suppl): 157 - 161.

Babinski J. (1902) Sur le role du cervelet dans les actes volitionnels nécessitant une succession rapide de mouvements (diadococinesie). Revue Neurologique 10: 1013-1015. See also Babinski J. (1913). Exposés des Travaux Scientifiques; Paris for original accounts of asynergia and dysmetria: pp 116 - 157.

Ramon y Cajal (1897-1904) Textura del sistema nervioso del hombre y de los vertebrados. 3 volumenes. Madrid 1897; 1899; 1904 Translation by Dr L Azoulay as: Histologie du systeme nerveux de l'homme et des vertebres. 2 volumes Paris: 1909 - 1911. Translated into American by Neely Swanson and Larry W Swanson as Histology of the Nervous System of Man and Vertebrates. 2 volumes. Oxford University Press: New York. 1995.

Blakemore WF (1973) Demyelination of the superior cerebellar peduncle in the mouse induced by cuprizone. Journal of the Neurological Sciences 20: 63 - 72.

Blakemore WF (1974) Remyelination of the superior cerebellar peduncle in old mice following demyelination induced by cuprizone . Journal of the Neurological Sciences 22: 121-126.

Reynolds R. , Wilkin GP (1991) Oligodendroglial progenitor cells but not oligodendroglia divide during normal development of the rat cerebellum. Journal of Neurocytology 20: 216 - 224.

Ludwin SK (1978) Central nervous system demyelination and remyelination in the mouse. Laboratory Investigation 39: 597 - 612.

Komoly S. , Hudson LD , deF Webster H. , Bondy CA (1992) Insulin-like growth factor 1 gene expression is induced in astrocytes during experimental demyelination. Proceedings of the National Academy of Sciences of the USA 89: 1894 -1898.

Yao D-L. , Liu X. , Hudson LD , Webster H deF. (1995) Insulin-like growth factor 1 treatment reduces demyelination and up-regulates gene expression of myelin related proteins in experimental autoimmune encephalomyelitis . Proceedings of the National Academy of Sciences of the USA 92: 6190 - 6194.

Barres BA et al. (1992) Cell death and control of cell survival in the oligodendrocyte lineage. Cell 70: 31 - 46.

Ogata J. , Feigin I. (1975) Schwann cells and regenerated peripheral myelin in multiple sclerosis: an ultrastructural study. Neurology 25: 713 - 716.

Blakemore WF (1977) Remyelination of CNS axons by Schwann cells transplanted from the rat sciatic nerve. Nature 266: 68 - 69.

Felts PA , Smith KJ (1992) Conduction properties of central nerve fibres remyelinated by Schwann cells. Brain Research 574: 178 -192.

Franklin Rjm , Crang AJ , Blakemore WF (1991) Transplanted type-1 astrocytes facilitate repair of demyelinating lesions by host oligodendrocytes in adult rat spinal cord. Journal of Neurocytology 20: 420 - 430.

Wood PM , Bunge RP (1991) The origin of remyelinating cells in the adult central nervous system: the role of the mature oligodendrocyte. Glia 4: 225-232.

Muir D. , Compston Das. (1996) Growth factor stimulation triggers apoptotic cell death in mature rat oligodendrocytes. Journal of Neuroscience Research 44: 1 -11.

Trotter J. , Crang AJ , Schachner M. , Blakemore WF (1993) Lines of glial precursor cells immortalised with a temperature-sensitive oncogene give rise to astrocytes and oligodendrocytes following transplantation into demyelinated lesions in the central nervous system. Glia 9: 25-40.

Barnett SC , Franklin RJ , Blakemore WF (1993) In vitro and in vivo analysis of a rat bipotential O - 2A progenitor cell line containing the temperature sensitive mutant gene of the SV 40 large T antigen. European Journal of Neuroscience 5: 1247 - 1260.

Groves K. et al. (1993) Repair of demyelinated lesions by transplantation of purified 0 - 2A progenitor cells. Nature 362: 453 - 455.

Warrington AE , Barbarese E. , Pfeiffer SE (1993) Differential myelinogenic capacity of specific developmental stages of the oligodendrocyte lineage upon transplantation into hypomelinating hosts. Journal of Neuroscience Research 34: 1-13.

Sussman J. , Targett M. , Compston Das , Blakemore WF (1996) Successful remyelination of adult axons by adult rat oligodendroglia. (Submitted).

Targett MP et al. (1996) Failure to remyelinate rat axons following transplantation of glial cells obtained from the adult human brain. Neuropathology and Applied Neurobiology 22: 199-206.

Gumpel M. , Baumann N. , Raoul M. , Jacque C. (1983) Survival and differentiation of oligodendrocytes from neural tissue transplanted into new-born mouse brain. Neuroscience Letters 37: 307 - 311.

Gumpel M. et al. (1987) Transplantation of human embryonic oligodendrocytes into shiverer brain. Annals of the New York Academy of Sciences 495: 71 - 85.

Seilhean D. et al. (1996) Myelination by transplanted human and mouse central nervous system tissue after long-term cryopreservation . Acta Neuropathologica 91: 82-88.

Utzschneider D. , Black JA , Kocsis JD (1992) Conduction properties of spinal cord axons in the myelin deficient rat mutant . Neuroscience 49: 221-228.

Utzschneider D. et al. (1994) Transplantation of glial cells enhances action potential conduction of amyelinated spinal cord axons in the myelin deficient rat. Proceedings of the National Academy of Sciences of the USA 91: 53- 57.

Baron-van Evercooren A. et al. (1996) Cell-cell interactions during the migration of myelin-forming cells transplanted in the demyelinated spinal cord. Glia 16: 147 -164.

Franklin Rjm , Bayley SA , Blakemore WF (1996) Transplanted CG-4 cells (an oligodendrocyte progenitor cell line) survive, migrate and contribute to repair of areas of demyelination in X-irradiated and damaged spinal cord but not in normal spinal cord. Experimental Neurology 137: 263 - 276.

Milner R. , ffrench Constant C. (1994) A developmental analysis of oligodendroglial integrins in primary cells: changes in av associated B subunits during differentiation . Development 120: 3497-3506.

Shaw CE , Milner RM , Compston Das , ffrench Constant C. (1996) Integrin expression during axo-glial interactions: a developmental comparison of oligodendrocytes and Schwann cells. Journal of Neuroscience 16: 1163- 1172.

Rodriguez M. , Lennon VA , Benviste EN , Merrill JE (1987) Remyelination by oligodendrocytes stimulated by antiserum to spinal cord. Journal of Neuropathology and Experimental Neurology 46: 84 - 95.

Asakura K. , Pogulis RJ , Pease LR , Rodriguez M. (1996) A monoclonal autoantibody which promotes central nervous system remyelination is highly polyreactive to multiple known and novel antigens. Journal of Neuroimmunology 65: 11 - 19.

Godfraind C. , Friedrich VL , Holmes KV , Dubois-Dalcq M. (1989) In vivo analysis of glial cell phenotypes during a viral demyelinating disease in mice. Journal of Cell Biology 109: 2405-2416.

Rodriguez M. , Pierce ML , Thiemann RL (1991) Immunoglobulins stimulate central nervous system remyelination: electronmicroscopic and morphometric analysis of proliferating cells. Laboratory Investigation 64: 358- 370.

Rodriguez M. , Lindsley MD (1992) Immunosuppression promotes CNS remyelination in chronic virus-induced demyelinating disease . Neurology 42: 348 - 357.

Charcot JM (1868) Histologie de la sclérose en plaques. Gazette Hopital (Paris) 41: 554-555; 557 - 558; 566.

Ozawa K. et al. (1994) Patterns of oligodendroglia pathology in multiple sclerosis. Brain 117: 1311-1322.

Davie CA et al. (1996) Persistent functional deficit in multiple sclerosis and autosomal dominant cerebellar ataxia is associated with axon loss. Brain 119: 715 - 722.

Mathews PM et al. (1996) Assessment of lesion pathology in multiple sclerosis using quantitative MRI morphometry and magnetic resonance spectroscopy . Brain 119: 715-722.

Meyer-Franke A. , Kaplan MR , Pfeiger FW , Barres BA (1995) Characterisation of the signalling interactions that promote the survival and growth of developing retinal ganglion cells in culture. Neuron 15: 805 - 819.