Abstract
These summaries, which are intended as a guide to current scientific research activity, are directed mainly at lay readers and as such they contain less technical scientific terminology and jargon than the original articles. The uneven length of the summaries is not a measure of their relative importance, rather it results from variation in the difficulty of explaining technical terms and concepts. For comprehensive details of the issues, methods, results and interpretations you are strongly advised to refer to the original article. Remember also that the published results of any single investigation should not be considered as definitive, or be interpreted in isolation, or reported out of context. Progress in the understanding of MS, as in any other field of science, requires critical debate and of ten must await independent confirmation offindings.
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