Koch-HenriksenNThygesenLCStenagerE, et al. Incidence of MS has increased markedly over six decades in Denmark particularly with late onset and in women. Neurology2018; 90(22): e1954–e1963.
2.
ProsperiniLLucchiniMRuggieriS, et al. Shift of multiple sclerosis onset towards older age. J Neurol Neurosurg Psychiatry. Epub ahead of print 27 April 2022. DOI: 10.1136/jnnp-2022-329049.
3.
Romero-PinelLBauLMatasE, et al. The age at onset of relapsing-remitting multiple sclerosis has increased over the last five decades. Mult Scler Relat Disord2022; 68: 104103.
4.
WaltonCKingRRechtmanL, et al. Rising prevalence of multiple sclerosis worldwide: Insights from the Atlas of MS, third edition. Mult Scler2020; 26(14): 1816–1821.
5.
MouresanEFMentesidouEBerglundA, et al. Clinical characteristics and long-term outcomes of late-onset multiple sclerosis: A Swedish nationwide study. Neurology2024; 102(6): e208051, https://journals.lww.com/10.1212/WNL.0000000000208051 (accessed 4 March 2024).
6.
AmatoMPFondericoMPortaccioE, et al. Disease-modifying drugs can reduce disability progression in relapsing multiple sclerosis. Brain2020; 143(10): 3013–3024.
7.
VaughnCBJakimovskiDKavakKS, et al. Epidemiology and treatment of multiple sclerosis in elderly populations. Nat Rev Neurol2019; 15(6): 329–342.
8.
LynchSBakerSNashatizadehM, et al. Disability measurement in multiple sclerosis patients 55 years and older: What is the Expanded Disability Status Scale really telling clinicians?Mult Scler Relat Disord2021; 49: 102724.
9.
ConfavreuxCVukusicS. Age at disability milestones in multiple sclerosis. Brain2006; 129(3): 595–605.
10.
BjornevikKMungerKLCorteseM, et al. Serum neurofilament light chain levels in patients with presymptomatic multiple sclerosis. JAMA Neurol2020; 77(1): 58–64.
11.
TutuncuMTangJZeidNA, et al. Onset of progressive phase is an age-dependent clinical milestone in multiple sclerosis. Mult Scler2013; 19(2): 188–198.
12.
PetraccaMRuggieriSNistriR, et al. Relationship between brain reserve and timing of clinical onset in multiple sclerosis. Mult. Scler2023; 29(3 Suppl.): 167 [poster presentation P040/925].