Frailty in multiple sclerosis: A closer look at the deficit accumulation framework

Abstract

Get full access to this article

View all access options for this article.

References

Searle

Mitnitski

Gahbauer

, et al. A standard procedure for creating a frailty index. BMC Geriatr 2008; 8: 24.

Belvisi

Canevelli

Baione

, et al. Operationalization of a frailty index in patients with multiple sclerosis: A cross-sectional investigation. Mult Scler 2021; 27(12): 1939–1947.

Ayrignac

Larochelle

Keezer

, et al. Frailty in ageing persons with multiple sclerosis. Mult Scler 2021; 27(4): 613–620.

Clegg

Bates

Young

, et al. Development and validation of an electronic frailty index using routine primary care electronic health record data. Age Ageing 2016; 45(3): 353–360.

Hanlon

Nicholl

Jani

, et al. Frailty and pre-frailty in middle-aged and older adults and its association with multimorbidity and mortality: A prospective analysis of 493 737 UK Biobank participants. Lancet Publ Health 2018; 3(7): e323–e332.