ScoldingNBarnesDCaderS. Association of British Neurologists: Revised (2015) guidelines for prescribing disease-modifying treatments in multiple sclerosis. Pract Neurol2015; 15: 273–279.
FoxRJThompsonABakerD. Setting a research agenda for progressive multiple sclerosis: The International Collaborative on Progressive MS. Mult Scler2012; 18: 1534–1540.
5.
PetkauJReingoldSCHeldU. Magnetic resonance imaging as a surrogate outcome for multiple sclerosis relapses. Mult Scler2008; 14: 770–778.
6.
BarkhofF. The clinico-radiological paradox in multiple sclerosis revisited. Curr Opin Neurol2002; 15: 239–245.
7.
KalincikTBuzzardKJokubaitisV. Risk of relapse phenotype recurrence in multiple sclerosis. Mult Scler2014; 20: 1511–1522.
8.
MowryEMPesicMGrimesB. Demyelinating events in early multiple sclerosis have inherent severity and recovery. Neurology2009; 72: 602–608.
9.
ConfavreuxCVukusicSAdeleineP. Early clinical predictors and progression of irreversible disability in multiple sclerosis: An amnesic process. Brain2003; 126: 770–782.
10.
LerayEYaouanqJLe PageE. Evidence for a two-stage disability progression in multiple sclerosis. Brain2010; 133: 1900–1913.
11.
SchutzerSEAngelTELiuT. Gray matter is targeted in first-attack multiple sclerosis. PloS One2013; 8: e66117.
12.
CalabreseMRomualdiCPorettoV. The changing clinical course of multiple sclerosis: A matter of gray matter. Ann Neurol2013; 74: 76–83.
13.
TremlettHYousefiMDevonshireV. Impact of multiple sclerosis relapses on progression diminishes with time. Neurology2009; 73: 1616–1623.
14.
ScalfariANeuhausADegenhardtA. The natural history of multiple sclerosis: A geographically based study 10: relapses and long-term disability. Brain2010; 133: 1914–1929.
15.
ScalfariANeuhausADaumerM. Early relapses, onset of progression, and late outcome in multiple sclerosis. JAMA Neurol2013; 70: 214–222.
16.
FisnikuLKBrexPAAltmannDR. Disability and T2 MRI lesions: A 20-year follow-up of patients with relapse onset of multiple sclerosis. Brain2008; 131: 808–817.
17.
BoscaICoretFValeroC. Effect of relapses over early progression of disability in multiple sclerosis patients treated with beta-interferon. Mult Scler2008; 14: 636–639.
18.
LublinFDBaierMCutterG. Effect of relapses on development of residual deficit in multiple sclerosis. Neurology2003; 61: 1528–1532.
19.
HirstCIngramGPearsonO. Contribution of relapses to disability in multiple sclerosis. J Neurol2008; 255: 280–287.
20.
KalincikTVivekVJokubaitisV. Sex as a determinant of relapse incidence and progressive course of multiple sclerosis. Brain2013; 136: 3609–3617.
21.
HirstCLIngramGPickersgillTP. Temporal evolution of remission following multiple sclerosis relapse and predictors of outcome. Mult Scler2012; 18: 1152–1158.
22.
BejaouiKRolakLA. What is the risk of permanent disability from a multiple sclerosis relapse?Neurology2010; 74: 900–902.
