The best basic science paper in multiple sclerosis in 2014: Important role for the choroid plexus in the central nervous system entry of leukocytes

Abstract

Get full access to this article

View all access options for this article.

References

Schwartz

Baruch

. The resolution of neuroinflammation in neurodegeneration: Leukocyte recruitment via the choroid plexus. EMBO J 2014; 1: 7–22.

Han

Lin

. Comprehensive immunophenotyping of cerebrospinal fluid cells in patients with neuroimmunological diseases. J Immunol 2014; 6: 2551–2563.

Cepok

Jacobsen

Schock

. Patterns of cerebrospinal fluid pathology correlate with disease progression in multiple sclerosis. Brain 2001; 11: 2169–2176.

Kunis

Baruch

Rosenzweig

. IFN-gamma-dependent activation of the brain’s choroid plexus for CNS immune surveillance and repair. Brain 2013; 11: 3427–3440.

Reboldi

Coisne

Baumjohann

. C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE. Nat Immunol 2009; 5: 514–523.

Kooij

Kopplin

Blasig

. Disturbed function of the blood-cerebrospinal fluid barrier aggravates neuro-inflammation. Acta Neuropathol 2014; 2: 267–277.

Stys

Zamponi

van Minnen

. Will the real multiple sclerosis please stand up? Nat Rev Neurosci 2012; 7: 507–514.