Abstract
Get full access to this article
View all access options for this article.
References
1.
Chang
A
Tourtellotte
WW
Rudick
R
. Premyelinating oligodendrocytes in chronic lesions of multiple sclerosis . N Engl J Med
2002 ; 346 : 165 –173 .
2.
Woodruff
RH
Fruttiger
M
Richardson
WD
. Platelet-derived growth factor regulates oligodendrocyte progenitor numbers in adult CNS and their response, following CNS demyelination . Mol Cell Neurosci
2004 ; 25 : 252 –262 .
3.
Mi
S
Hu
B
Hahm
K
. LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis . Nat Med
2007 ; 13 : 1228 –1233 .
4.
Atwal
JK
Chen
Y
Chiu
C
. A therapeutic antibody targeting BACE1 inhibits amyloid-β production in vivo . Sci Transl Med
2011 ; 3 : 84ra43.
5.
Kotter
MR
Li
WW
Zhao
C
. Myelin impairs CNS remyelination by inhibiting oligodendrocyte precursor cell differentiation . J Neurosci
2006 ; 26 : 328 –332 .
6.
Stoffels
JM
De Jonge
JC
Stancic
M
. Fibronectin aggregation in multiple sclerosis lesions impairs remyelination . Brain
2013 ; 136 : 116 –131 .
7.
Kotter
MR
Stadelmann
C
Hartung
HP.
Enhancing remyelination in disease: Can we wrap it up?
Brain
2011 ; 134 : 1882 –1900 .
8.
Deshmukh
VA
Tardif
V
Lyssiotis
CA
. A regenerative approach to the treatment of multiple sclerosis . Nature
2013 ; 502 : 327 –332 .
9.
Mei
F
Fancy
SP
Shen
YA
. Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis . Nat Med
2014 ; 20 : 954 –960 .
10.
Lee
S
Chong
SY
Tuck
SJ
. A rapid and reproducible assay for modeling myelination by oligodendrocytes using engineered nanofibers . Nat Protoc
2013 ; 8 : 771 –782 .