Treat patients with radiologically isolated syndrome when the MRI brain scan shows dissemination in time: No

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References

Okuda

Mowry

Beheshtian

. Incidental MRI anomalies suggestive of multiple sclerosis: The radiologically isolated syndrome. Neurology 2009; 72: 800–805.

Barkhof

Filippi

Miller

. Comparison of MRI criteria at first presentation to predict conversion to clinically definite multiple sclerosis. Brain 1997; 120: 2059–2069.

Liu

Kullnat

Simon

. Prevalence of the radiologically isolated syndrome among headache patients. American Society of Neuroradiology 49th Annual Meeting, Seattle, WA, USA, 4–9 June 2011 (abstract).

Granberg

Martola

Kristoffersen-Wilberg

. Radiologically isolated syndrome — incidental magnetic resonance imaging findings suggestive of multiple sclerosis, a systematic review. Mult Scler. [Epub ahead of print, 3 July 2012].

Gilbert

Sadler

. Unsuspected multiple sclerosis. Arch Neurol 1983; 40: 533–536.

Engell

. A clinical patho-anatomical study of clinically silent multiple sclerosis. Acta Neurol Scand 1989; 79: 428–430.

Lyoo

Seol

Byun

. Unsuspected multiple sclerosis in patients with psychiatric disorders: A magnetic resonance imaging study. J Neuropsychiatry Clin Neurosci 1996; 8: 54–59.

Zarei

Chandran

Compston

. Cognitive presentation of multiple sclerosis: Evidence of a cortical variant. J Neurol Neurosurg Psychiatry 2003; 74: 872–877.

Staff

Lucchinetti

Keegan

. Multiple sclerosis with predominant, severe cognitive impairment. Arch Neurol 2009; 66: 1139–1143.

10.

Lebrun

Blanc

Brassat

. Cognitive function in radiologically isolated syndrome. Mult Scler 2010; 16: 919–925.