Immunologic Correlates of MS Pathologic Subtypes

Asensio VC , Campbell IL. (1999) Chemokines in the CNS: Plurifunctional mediators in diverse states . Trends Neurosci 22: 504-512 .

Compston A , Ebers GC , Lassmann H , McFarland HF , Matthews B , Wekerle H. (1998) McAlpine’s Multiple Sclerosis. London: Churchill Livingstone .

Gerard C , Rollins BJ. (2001) Chemokines and disease . Nat Immunol 2: 108-115 .

Glabinski AR , Ransohoff RM. (1999) Chemokines and chemokine receptors in CNS pathology . J Neurovirol 5: 3-12 .

Hariharan D , Douglas SD , Lee B , Lai JP , Campbell DE , Ho WZ. (1999) Interferon-gamma upregulates CCR5 expression in cord and adult blood mononuclear phagocytes . Blood 93: 1137-1144 .

Lassmann H , Bruck W , Lucchinetti C. (2001) Heterogeneity of multiple sclerosis pathogenesis: Implications for diagnosis and therapy . Trends Mol Med 7: 115-121 .

Lucchinetti C , Bruck W , Parisi J , Scheithauer B , Rodriguez M , Lassmann H. (2000) Heterogeneity of multiple sclerosis lesions: Implications for the pathogenesis of demyelination . Ann Neurol 47: 707-717 .

Lucchinetti CF , Bruck W , Rodriguez M , Lassmann H. (1996) Distinct patterns of multiple sclerosis pathology indicates heterogeneity on pathogenesis . Brain Pathol 6: 259-274 .

Luster AD. (1998) Chemokines: Chemotactic cytokines that mediate inflammation . N Engl J Med 338: 436-445 .

MacKay CR. (2001) Chemokines: Immunology’s high impact factors . Nat Immunol 2: 95-101 .

Mennicken F , Maki R , de Souza EB , Quirion R. (1999) Chemokines and chemokine receptors in the CNS: A possible role in neuroinflammation and patterning . Trends Pharmacol Sci 20: 73-78 .

Rollins BJ. (1997) Chemokines . Blood 90: 909-928 .

Rottman JB , Slavin AJ , Silva R , Weiner HL , Gerard CG , Hancock WW. (2000) Leukocyte recruitment during onset of experimental allergic encephalomyelitis is CCR1 dependent . Eur J Immunol 30: 2372-2377 .

Sorensen TL , Tani M , Jensen J , Pierce V , Lucchinetti C , Folcik VA , Qin S , Rottman J , Sellebjerg F , Strieter RM , Frederiksen JL , Ransohoff RM. (1999) Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients . J Clin Invest 103: 807-815 .

Trebst C , Ransohoff RM. (2001) Investigating chemokines and chemokine receptors in patients with multiple sclerosis: Opportunities and challenges . Arch Neurol 58: 1975-1980 .

Trebst C , Sorensen TL , Kivisakk P , Cathcart MK , Hesselgesser J , Horuk R , Sellebjerg F , Lassmann H , Ransohoff RM. (2001) CCR1+/CCR5+ mononuclear phagocytes accumulate in the central nervous system of patients with multiple sclerosis . Am J Pathol 159: 1701-1710 .

Trebst C , Staaugaitis S , Kivisakk P , Mahad DJ , Cathcart MK , Tucky BH , Wei T , Sandhya Rani , Horuk R , Aldape K , Pardo C , Lucchinetti C , Lassmann H , Ransohoff RM. (2002) CC chemokine receptor 8 (CCR8) in the central nervous system is associated with phagocytic macrophages . Am J Pathol (in press).