Abstract
Background:
CD34-positive plaque-like dermal fibroma (PDF) is a poorly characterised benign dermal neoplasm that has a wide differential diagnosis. It can be mistaken for other entities on superficial biopsy and be overtreated, leading to unnecessary worry and extensive surgery.
Objective:
To report on an uncommon presentation of this entity, the histopathologic differential diagnosis of PDF, and a novel treatment method.
Methods:
Clinical and histopathological information was obtained for a PDF lesion on a 75-year-old man.
Results:
On superficial biopsy, the PDF lesion was misinterpreted as a possible neurothekeoma. Successful Mohs surgery and genetic testing confirmed the diagnosis of PDF, and the patient received appropriate tissue-sparing surgical management.
Conclusion:
This case adds to our current knowledge about PDF and highlights the importance of early recognition of these lesions to direct appropriate diagnostic testing (full-thickness biopsy) and management. This case confirms successful management with Mohs surgery.
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