Abstract
Background:
Psoriasis treatment involves multiple treatment arms. Treatment choice depends on many factors and may change, due to the chronicity of psoriasis.
Objective:
The purpose of our study is to explore reasons for treatment changes in patients with moderate to severe psoriasis.
Methods:
Ten charts of patients with moderate to severe psoriasis were reviewed. The medication changes and reasons for change were extracted. A “treatment change” was defined as switching between medication classes, adding or removing a medication class, or switching medications within the oral or biologic medication class.
Results:
Seventy-seven treatment changes were identified. On average, 1 treatment change occurred per year of follow-up. The most common reason for treatment change was inadequate disease control.
Conclusions:
Inadequate disease control with current therapy is the most common reason a physician changes treatment for moderate to severe psoriasis. More efficacious treatments or ways to improve efficacy may help improve the long-term outcomes of psoriasis.
Keywords
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