Ulcerative necrobiosis lipoidica (UNL) is an uncommon disease, which is frequently recalcitrant to available therapies. It is characterized by well-defined, ulcerated plaques with indurated borders and atrophic centers. Multiple therapeutic options have been described, with variable success rates.
Objective:
To report the efficacy of using topical tacrolimus in treating UNL.
Method:
Topical tacrolimus was used in the treatment of two patients with UNL.
Result:
Topical tacrolimus is effective in treating UNL.
Conclusion:
Topical tacrolimus is a reasonably effective choice in treating UNL.
Contexte:
La nécrobiose lipoïdique ulcérée (NLU) est une maladie rare, qui est souvent réfractaire au traitement. Elle se caractérise par des placards ulcérés et bien définis, des bords indurés et des centres atrophiques. Différentes formes de traitement ont été utilisées et se sont soldées par des taux variables de réussite.
Objectif:
L'étude visait à faire état de l'efficacité du tacrolimus topique dans le traitement de la NLU.
Méthode:
Nous avons fait usage de tacrolimus topique dans le traitement de la NLU chez deux patients.
Résultat:
Le tacrolimus topique s'est montré efficace dans le traitement de la NLU.
Conclusion:
Le tacrolimus topique est un moyen relativement efficace de traitement de la NLU.
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