Factors influencing distal radial artery occlusion after hepatocellular carcinoma intervention via distal transradial access

Abstract

Purpose:

Limited research exists on the incidence of distal radial artery occlusion (d-RAO) following distal transradial access (d-TRA) for interventional therapy in hepatocellular carcinoma (HCC), and the associated risk factors remain poorly characterized. In this study, we aimed to systematically determine the temporal incidence patterns and modifiable predictors of d-RAO at defined postoperative intervals (24 h, 1/3/6 months) among HCC patients undergoing d-TRA-based interventions.

Methods:

This prospective, single-center study conducted between August 2023 and June 2024 enrolled 378 patients who underwent d-RAO assessments at 24 h, 1 month, 3 months, and 6 months following transradial intervention for HCC. Univariate and multivariate analyses were performed to identify predictive factors associated with d-RAO development.

Results:

Following d-TRA-based interventions for HCC, the incidence rates of d-RAO were 16.40% at postoperative day 2, 11.90% at 1 month, 8.20% at 3 months, and 6.35% at 6 months. Significant differences in smoking status and procedural factors were observed between the d-RAO group and the non-occlusion group. After adjusting for other confounding variables, smoking and prolonged puncture duration were identified as independent risk factors for d-RAO.

Conclusions:

D-RAO represents a clinically significant complication in transradial interventional therapy for HCC. Elucidating its modifiable risk factors and predictive determinants may aid in the development of targeted preventive strategies.