Mid Thigh Pain (MTP), i.e. a continuous dull pain in the thigh present after prolonged weight-bearing, is a common experience in hip arthroplasties. Since its origin is not clear, the Authors try to explain its etiology and pathogenesis through an analysis of a selection of their cases and of the literature. MTP seems to be a signal of bone overloading at the interface with the prosthesis; the overloading causes biochemical changes in the fibrous tissue surrounding the femoral component, which, in turn, provokes a bone resorption enhancing movements and overloading. If not treated with unloading, MTP may result in stem loosening.
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