Specific fundus changes have been reported in patients with membranoproliferative glomerulonephritis type II (MPGN type II). We studied the clinical course of this retinopathy in four patients who all had a long follow-up with several fundus examinations. Sequential observation was indicative of a slow progression of the retinopathy. Most eyes maintained in the chronic stages a nearly normal visual acuity, and a full visual field despite the existence of marked drusen and atrophic changes. The prognosis however must be somewhat guarded, since choroidal neovascularization developed in three eyes and caused bilateral severe visual loss in one patient
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Duvall-YoungJ., ShortC.D., RainesM.F., GokalR., LawlerW.. Fundus changes in mesangiocapillary glomerulonephritis type II: clinical and fluorescein angiographic findings. Br J Ophthalmol1989; 73: 900–6.
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LeysA., ProesmansW., Van Damme-LombaertsR., Van DammeB.. Specific eye fundus lesions in type II membra-noproliferativ glomerulonephritis. Pediatr Nefrol (in press).
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LeysA., MichielsenB., LeysM., VanrenterghemY., MissottenL., Van DammeB.. Subretinal neovascular membranes associated with chronic membranoproliferative glomerulonephritis type II (dense deposit disease). Graefe's Arch Clin Exp Ophthalmol1991; 229(in press).
