Abstract
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An 82-year-old Greek male with left neovascular age-related macular degeneration presented for his 10-weekly aflibercept injection (pre-filled syringes). He previously received bevacizumab and aflibercept (vials) and had uncomplicated left cataract surgery.
He was incidentally found to have asymptomatic left eye intravitreal silicone oil droplets. Fundus imaging, OCT (Figure 1(a)) and B-scan (Figure 1(b)) confirmed the largest droplet anterior to the macula, measuring 3.01 mm (estimated volume 0.014 ml). Intraocular pressure was 15 mmHg. Review of prior wide-field fundus autofluorescence (Figure 1(c)) and pseudo-colour imaging (Figure 1(d)) confirmed the droplets were present for at least two years.
Silicone oil droplets occur in up to 70% of patients post intravitreal injections. Most are asymptomatic, although some cause floaters.1,2 The largest droplet to date measured 1.3 mm (estimated volume 0.001 ml) 3 ; ours is fourteenfold larger. Intervention is generally not required unless floaters are bothersome, in which case vitrectomy has been suggested.2,3
Footnotes
Acknowledgments
None.
Ethics approval and consent to participate
Ethical approval is not required for this study in accordance with local or national guidelines. Written informed consent was obtained from the patient for publication of the details of their medical case and any accompanying images.
Consent for publication
Written informed consent was obtained from the patient for publication of the details of their medical case and any accompanying images.
Authors’ contributions
LC, SD and WC performed the ophthalmic examination on the patient. TM gathered data, analysed and interpreted it. TM was a major contributor to the writing of the manuscript. LC, SD and WC all contributed in writing and editing the manuscript. All authors read and approved the manuscript.
Funding
The authors received no financial support for the research, authorship, and/or publication of this article.
Declaration of conflicting interests
The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Data availability
The data that support the findings of this study are not publicly available due to patient confidentiality reasons. However, they are available from the corresponding author upon reasonable request.