Optic disc morphometry using spectral domain optical coherence tomography in a Nigerian population

Abstract

Purpose:

To assess morphological optic disc dimensions using spectral-domain optical coherence tomography (OCT) in a Nigerian population.

Materials and method:

Good quality SD-OCT scans of the optic disc of 147 eyes of 88 participants were selected, enrolled, and retrospectively reviewed. All subjects had optic nerve head and retinal nerve fibre layer OCT imaging, as well as analysis, done using the Topcon 3D OCT-1 Maestro^®. The age, sex, and some OCT-generated optic disc dimensions namely disc area (DA), vertical disc diameter (VDD), horizontal disc diameter (HDD) were retrieved from the database and analyzed.

Results:

The mean age of the study subjects was 52.6±20.9 years with a range of 8–90 years; male to female ratio was 1:1.3. The right eye and left eye accounted for 75 and 72 of the 147 scans respectively. The mean DA, VDD, and HDD were 2.54 ± 0.48 mm², 1926.5 ± 189.6 μm and 1673.9 ± 173.9 μm, respectively. Males had significantly larger DA than females (2.56 ± 0.53 mm² vs 2.51 ± 0.44 mm², p = 0.043). The mean DA and VDD of eyes of subjects aged 21–40 years were significantly higher compared to subjects aged 60 years and more (p = 0.008 and 0.001, respectively).

Conclusion:

The mean optic disc area and diameters are larger than those reported in similar studies involving blacks and other races. The mean disc area reduces with increasing age.