To present an infant with bilateral ocular and skin involvement by juvenile xanthogranuloma and the results of treatment with vinblastine.
Methods
Analysis of the clinical and histopathologic data and the results of the treatment.
Results
After 14 months' evolution with no response to other treatments, the lesions responded to a course of vinblastine (6 mg/m2/weekly, corrected for weight), which was followed by a maintenance treatment for 52 weeks.
Conclusions
The treatment protocol used in the present case may prove useful for similar patients. We found no other report describing these results.
BlankH., EglickP.G., BeermanH.Nevoxanthoendothelioma with ocular involvement.Pediatrics1949; 4: 349–54.
6.
ChaudhryI.A., Al-JishiZ., ShamsiF.A., RileyF.Juvenile xanthogranuloma of the corneoscleral limbs: case report and review of the literature.Surv Ophthalmol2004; 49: 8–14.
