Quantitative Assessment of Anterior Chamber Volume using Slit-Lamp OCT and Pentacam

Abstract

Purpose

To quantitatively assess and compare the anterior chamber volume (ACV) by different anterior segment imaging techniques.

Methods

Forty healthy eyes of 40 patients were recruited and three consecutive measurements of ACV were determined prospectively utilizing SL-OCT and Pentacam. Statistical significance of interdevice differences between measurements was evaluated by unpaired t test and Bland-Altman analysis. The repeatability of three consecutive measurements was analyzed by repeated measured analysis of variance.

Results

Eighty eyes of 40 patients (18 female, 22 male) with a mean spherical error of −0.55±1.4 diopters were included in the study. Mean ACV were detected as 163.34±29.76 mm³ by Pentacam and 164.14±28.44 mm³ by SL-OCT (unpaired t test, p=0.872). Pentacam and SL-OCT displayed a high intrasession repeatability (repeated measured analysis of variance, p>0.05). ACV values detected by SL-OCT were clinically interchangeable with Pentacam.

Conclusions

Noncontact measurements of ACV using SL-OCT and Pentacam were easy to handle and demonstrated good repeatability. The tested devices were regarded as compatible in measuring ACV.