Rapid Development of Band Keratopathy of Corneal Graft Associated with Treatment with Intracameral Recombinant Tissue Plasminogen Activator for Postoperative Fibrin Reaction
Restricted accessAnnouncementFirst published online May, 2007
Rapid Development of Band Keratopathy of Corneal Graft Associated with Treatment with Intracameral Recombinant Tissue Plasminogen Activator for Postoperative Fibrin Reaction
To report a corneal transplant complication associated with intracameral recombinant tissue plasminogen activator (rTPA) treatment of postoperative fibrin reaction.
Methods.
In a 71-year-old patient, a triple procedure was performed for perforated rheumatic ulcer and secondary cataract.
Results.
A dense band keratopathy developed rapidly within 36 hours after the use of intracameral injection of rTPA for the treatment of a dense fibrin clot.
Conclusions.
This is the first report of rapid development of massive band keratopathy in a corneal graft after triple procedure and treatment with intracameral rTPA. Intracameral rTPA should be used with caution in patients with attenuated endothelium.
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