Restricted accessAnnouncementFirst published online 2007-5
Rapid Development of Band Keratopathy of Corneal Graft Associated with Treatment with Intracameral Recombinant Tissue Plasminogen Activator for Postoperative Fibrin Reaction
To report a corneal transplant complication associated with intracameral recombinant tissue plasminogen activator (rTPA) treatment of postoperative fibrin reaction.
Methods.
In a 71-year-old patient, a triple procedure was performed for perforated rheumatic ulcer and secondary cataract.
Results.
A dense band keratopathy developed rapidly within 36 hours after the use of intracameral injection of rTPA for the treatment of a dense fibrin clot.
Conclusions.
This is the first report of rapid development of massive band keratopathy in a corneal graft after triple procedure and treatment with intracameral rTPA. Intracameral rTPA should be used with caution in patients with attenuated endothelium.
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