Abstract
Purpose
To evaluate the results of short wavelength perimetry (SWAP) of ocular hypertensive (OHT) patients and correlate these findings with central corneal thickness (CCT) measurements.
Methods
Thirty-seven OHT patients with a mean age of 50.2±8.2 (SD) years and 30 control subjects with a mean age of 50.3±8.5 (SD) years were included in this study. A questionnaire was applied to patients to evaluate the demographic risk factors that may predict glaucoma development. After a detailed ophthalmologic examination, achromatic and short wavelength perimetries and ultrasonic pachymetry were performed and the results were compared between the two groups with Student t test and Mann-Whitney U test. A p value <0.05 is considered as statistically significant.
Results
Mean CCT was higher in the OHT group (right eye; 558.13±28.39 μm and left eye; 558.94±27.30μm) when compared with the control subjects (524.66±30.53 μm and 525.86±30.46 μm, respectively) (p<0.01). A significant positive correlation was found between CCT measurements and intraocular pressure (r=0.5, p<0.001). Four right eyes (10.8%) and five left eyes (13.5%) of OHT patients had defects in SWAP. OHT patients with SWAP abnormalities had significantly lower CCT measurements in right (527.25±17.34 μm) and left eye (528.80±13.60 μm) when compared with OHT patients without SWAP defects (561.87±27.29 μm and 563.65±25.92 μm, respectively) (p<0.05). Significant correlations were found between CCT and SWAP MD, PSD, and CPSD (p<0.05).
Conclusions
OHT patients with SWAP abnormalities had significantly lower CCT measurements than those without. CCT is considered as a risk factor for the development of glaucomatous damage in OHT patients.
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