Abstract
Purpose
To evaluate changes in retinal nerve fiber layer (RNFL) thickness after laserin situ keratomileusis (LASIK) using a scanning laser Polarimeter with fixed corneal compensation (GDx) and the retinal thickness analyzer (RIA).
Methods
Thirty-eight eyes of 19 healthy subjects (10 female and 9 male; mean age 37.0±8.8 years) underwent GDx and RTA measurements before and after LASIK. All subjects revealed mild to high myopia (mean spherical refraction: −4.0±2.75 D). Measurements using GDx were followed by RTA measurements after pupil dilation. All measurements were performed the day before LASIK and 1 week postoperatively.
Results
GDX revealed a decrease in nerve fiber layer thickness measurements after LASIK, but did not reach statistical significance (p>0.05). Using RTA, mean RNFL thickness (MRNFL) and RNFL cross sectional area decreased significantly after LASIK (p=0.03 and p=0.02, respectively).
Conclusions
Scanning laser polarimetry revealed a slight decrease in RNFL thickness measurements after LASIK. MRNFL and RNFL cross section were significantly lower after LASIK using RTA. The changes might be artifacts in a small group of myopic subjects.
Keywords
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