To report hypo-estrogenemic state in a case of recurrent vitreous hemorrhages due to primary antiphospholipid antibody syndrome.
Methods
Interventional case report. A 40-year-old woman presented with recurrent vitreous hemorrhages. Treated initially with laser photocoagulation followed by hormone replacement therapy.
Results
Cessation of vitreous hemorrhage since starting hormone replacement therapy (twenty months ago).
Conclusions
This is the first documented case of hypo-estrogenemia in lupus anticoagulant retinopathy. The response of this condition to estrogen is worth exploring.
Glacet-BernardA.BayaniN.ChretienP.CochardC.LelongF.CoscasG.. Antiphospholipid antibodies in retinal vascular occlusions. A prospective study of 75 patients.Arch Ophthalmol1994; 112: 790–5.
3.
PulioJ.S.WardLM. Antiphospholipid antibodies associated with retinal vascular disease.Retina1987; 7: 215–8.
4.
LureauM.A.Glacet-BernardA.CoscasG.. Bilateral central retinal vein occlusion and circulating anticoagulant.J Fr Ophtalmol1995; 18: 468–72.
SuzukiA.OkamotoN.WatanabeM.KiritoshiH.MotokuraM.FukudaM.. The time course of white retinal arterioles in two cases of antiphospholipid antibody syndrome.Nippon Ganka Gakkai Zasshi1998; 102: 455–61.
7.
PauH.CarneyAS.WalkerR.MurtyG.E.. Is oestrogen therapy justified in the treatment of hereditary haemorrhagic telangiectasia: a biochemical evaluation.Clinical Otolaryngology & Allied Sciences2000; 25: 547–50.
8.
Van CustemE.. Oestrogen-progesterone, a new therapy of bleeding gastrointestinal vascular malformations.Acta Gastroenterol Bel1993; 56: 2–10.