Abstract
Purpose
To report a case presenting with dacryoadenitis as the earliest manifestation of systemic Wegener's granulomatosis (WG).
Design
Observational case report.
Methods
A 41-year-old woman initially presented symptoms of bilateral dacryoadenitis. She subsequently developed upper and lower respiratory tract involvement, scleritis and keratitis.
Results
Cytoplasmic antineutrophil antibody (c-ANCA) titer was positive. The lacrimal gland and lung biopsies were consistent with WG. The patient responded well to cyclophosphamide and prednisolone.
Conclusions
Dacryoadenitis may be the earliest presenting manifestation of WG and prompt immunosuppressive chemotherapy may control it preventing the limited disease from progressing to a complete form and reducing its morbidity and mortality
Get full access to this article
View all access options for this article.