THE HISTOCHEMICAL LOCALIZATION OF HISTIDINE IN THE HUMAN EPIDERMIS AND ITS RELATIONSHIP TO ZINC BINDING

Abstract

A concentration of histidine in the transitional zone of the human epidermis has been identified by the diazonium coupling reaction. It has been concluded that histidine may be largely responsible for the selective in vitro zinc-binding property of the transitional zone of keratin formation in the epidermis.