The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of Basic Yellow 57, which is reported to function as a hair dye in cosmetic products. The Panel reviewed the available data to determine the safety of this ingredient. The Panel concluded that Basic Yellow 57 is safe for use as a hair dye ingredient in the present practices of use and concentration described in this safety assessment.
NikitakisJKowczA. Web-Based International Cosmetic Ingredient Dictionary and Handbook. Washington, DC: Personal Care Products Council. https://webdictionary.personalcarecouncil.org/jsp/Home.jsp. Last Updated 2021. Accessed March 05, 2021.
Scientific Committee on Cosmetic and Non-Food Products (SCCNFP). Opinion of the Scientific Committee on Cosmetic Products and Non-Food Products Intended for Consumers Concerning Basic Yellow 57 (Colipa No. C10). SCCNFP/0679/03. 2003. https://ec.europa.eu/health/ph_risk/committees/sccp/documents/out217_en.pdf. Accessed March 30, 2021.
US Food and Drug Administration (FDA) Center for Food Safety & Applied Nutrition (CFSAN). Voluntary Cosmetic Registration Program (VCRP) - frequency of use of cosmetic ingredients. College Park, MD Obtained under the Freedom of Information Act from CFSAN; requested as “Frequency of Use Data” January 4, 2021; received January 21, 2021; 2021.
7.
Personal Care Products Council. Concentration of use by FDA product category: basic yellow 57. Unpublished data submitted by the Personal Care Products Council on January 6, 2021; 2021.
8.
ThyssenJPSøstedHUterW, et al.Self-testing for contact sensitization to hair dyes - scientific considerations and clinical concerns of an industry-led screening programme. Contact Dermat. 2012;66(6):300-311.
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GoossensA. Self-testing for contact sensitization to hair dyes. Contact Dermat. 2012;66(6):299.
AlepeeNHibatallahJKlaricMMewesKRPfannenbeckerUMcNameeP. Assessment of cosmetic ingredients in the in vitro reconstructed human epidermis test method EpiSkin™ using HPLC/UPLC-spectrophotometry in the MTT-reduction assay. Toxicol In Vitro. 2016;33:105-117.
