The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of Basic Brown 17, which is reported to function as a hair dye in cosmetic products. The Panel reviewed the available data to determine the safety of this ingredient. The Panel concluded that Basic Brown 17 is safe in the present practices of use and concentration described in this safety assessment for use in hair dye products, and that the available data are insufficient to make a determination that Basic Brown 17 is safe under the intended conditions of use in other types of cosmetic products.
NikitakisJKowczA. Web-Based International Cosmetic Ingredient Dictionary and Handbook. Washington, DC: Personal Care Products Council. Last Updated 2019. https://webdictionary.personalcarecouncil.org/jsp/Home.jsp. Accessed August 28, 2019.
US Food and Drug Administration (FDA) Center for Food Safety & Applied Nutrition (CFSAN). Voluntary Cosmetic Registration Program (VCRP) - Frequency of Use of Cosmetic Ingredients. College Park, MD Obtained under the Freedom of Information Act from CFSAN; Requested as “Frequency of Use Data”; 2021. January 4, 2021; received January 21, 2021.
8.
Personal Care Products Council. Concentration of Use by FDA Product Category - Basic Brown 17; 2019. Unpublished data submitted by the Personal Care Products Council on February 1, 2019.
9.
ThyssenJPSostedHUterW, et al.Self-testing for contact sensitization to hair dyes - scientific considerations and clinical concerns of an industry-led screening programme. Contact Dermat. 2012;66(6):300-311.
10.
GoossensA. Self-testing for contact sensitization to hair dyes. Contact Dermat. 2012;66(6):299.
SteilingW. The bioavailability of cationic azo hair dyes: application of a new in vitro method. Altern Lab Anim. 2004;32 Suppl 1B(Suppl 1B):689-692.
13.
Tafurt-CardonaYSuares-RochaPFernandesTCCMarin-MoralesMA. Cytotoxic and genotoxic effects of two hair dyes used in the formulation of black color. Food Chem Toxicol. 2015;86:9-15.
14.
Vanden BroeckeKBruzeMPerssonLDerooHGoossensA. Contact urticaria syndrome caused by direct hair dyes in a hairdresser. Contact Dermat. 2014;71(2):124-126.
