Abstract

Greetings!
Summer 2019 has flown by, Fall is upon us, and the American College of Toxicology’s (ACT’s) 2019 Annual Meeting is on the horizon. This year’s Annual Meeting is particularly special, as we will celebrate the 40th anniversary of ACT’s very first Annual Meeting in 1979!
Another special feature of the Annual Meeting, related to International Journal of Toxicology, is that the awardees of the 2019 Best Paper published in International Journal of Toxicology will be recognized at the Awards Luncheon. The award recipients are Armaghan Emami, Jeff Tepper, Brian Short, Tony Yaksh, Alison Bendele, Thulasi Ramani, Alvaro Cisternas, Jay Chang, and R. Daniel Mellon for their paper “Toxicology evaluation of drugs administered via uncommon routes: Intranasal, intraocular, intrathecal/intraspinal, and intra-articular.” The winning paper was published in the January 2018 issue of the journal. While you can access the paper now, or whenever you’d like to do so, look for a forthcoming podcast featuring one or more of the authors; the podcast will be available to readers who access the winning paper.
The current issue of International Journal of Toxicology features an interesting mix of papers. Among these are 2 review articles, with one covering the topic of central nervous system testing under ICH S7A (Gauvin et al), and the other on the topic of the toxicology of various forms of gold nanoparticles (Adewale et al). We have also included 2 articles on developmental and reproductive toxicology studies: one of these focuses on vedolizumab, an integrin α4β7 receptor agonist (Crawford and Friedman), and the other on fluoride (Bartos et al). Just a comment about the Bartos et al publication: Although the exposure concentrations of fluoride used in these studies are somewhat higher that the levels used to treat municipal drinking water supplies (which is usually on the order of 1 ppm), it’s important to realize that the naturally occurring levels of fluoride in ground water can be considerably higher, and, in fact, concentrations of 5 to 10 ppm, which were used in this study, are not out of line with reports of naturally occurring drinking water fluoride concentrations.
I’d like to also point out some features of the “Journal” tab on the ACT website (http://www.actox.org/journal/intlJournal.asp). In addition to providing access to articles in the current issue, past issues, and upcoming papers (OnlineFirst), you can see the papers that are currently most accessed and cited (this feature is updated weekly). Also, please browse our “Collections” that are featured near the bottom of the web page. We feature one Collection each for our most read articles in 2017 and 2018, and another Collection highlights recently published papers in International Journal of Toxicology on nanomaterials and nanotoxicology. The current issue’s gold nanoparticle paper, as well as a new paper on an alternative method to screen for nanotoxicity in vitro by Guo et al, are included in the “Recommended Reading on Nanomaterials” Collection.
I’m looking forward to seeing many of you in November. As always, I appreciate your suggestions and ideas.
