This review highlights published literature in 2023 that is related to the anesthetic management of patients with congenital heart disease (CHD). Though not inclusive of all topics, 31 articles are discussed and four primary themes emerged: transfusion and hemostasis, outcomes and risk assessment, monitoring, and pharmacology.
IngRJTwiteMD. The year in review: anesthesia for congenital heart disease 2013. Semin CardioThorac Vasc Anesth. 2014;18:17-23.
2.
BohutaLCharetteKChanT, et al.Encouraging results of blood conservation in neonatal open-heart surgery. J Thorac Cardiovasc Surg. 2024;167:1154-1163.
3.
BusackCRanaMSBeidasYAlmiranteJMDeutschNMatisoffA. Intraoperative blood product transfusion in pediatric cardiac surgery patients: a retrospective review of adverse outcomes. Paediatr Anaesth. 2023;33:387-397.
4.
DuttaPEmaniSNathanMEmaniSIblaJC. Implications of transfusion in adults with congenital heart disease undergoing cardiac surgery. Pediatr Cardiol. 2023;44:218-227.
5.
SultanIBiancoVBrownJA, et al.Long-term impact of perioperative red blood cell transfusion on patients undergoing cardiac surgery. Ann Thorac Surg. 2021;112:546-554.
6.
TangMRavnHBAndreasenJJ, et al.Fewer transfusions are still more—red blood cell transfusions affect long-term mortality in cardiac surgery. Eur J Cardio Thorac Surg. 2023;63:ezad101.
7.
AdNMassimianoPSRongioneAJ, et al.Number and type of blood products are negatively associated with outcomes after cardiac surgery. Ann Thorac Surg. 2022;113:748-756.
8.
AhmedMAcostaSIHoffmanGMTweddellJSGhanayemNS. Mathematical analysis of hemoglobin target in univentricular parallel circulation. J Thorac Cardiovasc Surg. 2023;166:214-220.
9.
FaraoniDDiNardoJA. Commentary: red blood cells transfusion in patients undergoing congenital cardiac surgery: still far from physiology-based practice. J Thorac Cardiovasc Surg. 2024;167:e24-e26.
10.
RanucciMDi DeddaUIsgròG, et al.Plasma-free strategy for cardiac surgery with cardiopulmonary bypass in infants <10 kg: a retrospective, propensity-matched study. J Clin Med. 2023;12:3907.
11.
OliverWCBeynenFMNuttallGA, et al.Blood loss in infants and children for open heart operations: albumin 5% versus fresh-frozen plasma in the prime. Ann Thorac Surg. 2003;75:1506-1512.
12.
MiaoXLiuJZhaoM, et al.Evidence-based use of FFP: the influence of a priming strategy without FFP during CPB on postoperative coagulation and recovery in pediatric patients. Perfusion. 2015;30:140-147.
13.
DesboroughMJSanduRBrunskillSJ, et al.: Fresh frozen plasma for cardiovascular surgery. Cochrane Database Syst Rev. 2021;2015:CD007614.
14.
DieuARosal MartinsMEeckhoudtS, et al.Fresh frozen plasma versus crystalloid priming of cardiopulmonary bypass circuit in pediatric surgery: a randomized clinical trial. Anesthesiology. 2020;132:95-106.
15.
BenegniSGiorniCRaggiV, et al.Diagnostic agreement between TEG5000 and TEG6S in the assessment of hemostasis in pediatric cardiac surgery: a prospective non-inferiority study. Pediatr Cardiol2023;1-7. doi:10.1007/s00246-023-03311-w
16.
GautamNTranVGriffinE, et al.A single‐center, retrospective analysis to compare measurement of fibrinogen using the TEG6 analyzer to the clauss measurement in children undergoing heart surgery. Pediatr Anesthesia2023. doi:10.1111/pan.14820
17.
SiemensKHuntBJParmarKTaylorDSalihCTibbySM. Factor XIII levels, clot strength, and impact of fibrinogen concentrate in infants undergoing cardiopulmonary bypass: a mechanistic sub-study of the FIBCON trial. Br J Anaesth. 2023;130:175-182.
18.
NavaratnamMMendozaJMZhangS, et al.Activated 4-factor prothrombin complex concentrate as a hemostatic adjunct for neonatal cardiac surgery: a propensity score-matched cohort study. Anesth Analg. 2023;136:473-482.
19.
FullerSKumarSRRoyN, et al.The American association for thoracic surgery congenital cardiac surgery working group 2021 consensus document on a comprehensive perioperative approach to enhanced recovery after pediatric cardiac surgery. J Thorac Cardiovasc Surg. 2021;162:931-954.
20.
GoodmansonMMLathamGJLandsemLMRossFJ. The year in review: anesthesia for congenital heart disease 2022. Semin CardioThorac Vasc Anesth. 2023;27:114-122.
21.
RossFJJoffeDCLandsemLMLathamGJ. The year in review: anesthesia for congenital heart disease 2021. Semin CardioThorac Vasc Anesth. 2022;26:129-139.
22.
OnurTKaracaÜOnurA, et al.Factors affecting extubating time of postoperative patients who underwent congenital cardiac surgery: a randomized prospective study. Eur Rev Med Pharmacol Sci. 2023;27:763-772.
23.
LiJWangXLiuWWenSLiX. Remote ischemic preconditioning and clinical outcomes after pediatric cardiac surgery: a systematic review and meta-analysis. BMC Anesthesiol. 2023;23:105.
24.
HuangJTangJFanYWangDYeL. Risk factors associated with prolonged intensive care unit stay following surgery for total anomalous pulmonary venous connection: a retrospective study. J Cardiothorac Surg. 2023;18:257.
25.
SimpaoAFRandazzoIRChittamsJL, et al.Anesthesia and sedation exposure and neurodevelopmental outcomes in infants undergoing congenital cardiac surgery: a retrospective cohort study. Anesthesiology. 2023;139:393-404.
26.
BackerCLOvermanDMDearaniJA, et al.Recommendations for centers performing pediatric heart surgery in the United States. J Thorac Cardiovasc Surg. 2023;166:1782-1820.
27.
Section on Cardiology and Cardiac SurgeryAmerican Academy of Pediatrics. Guidelines for pediatric cardiovascular centers. Pediatrics. 2002;109:544-549.
28.
LinAYHabibAKoR, et al.Adverse events in the pediatric cardiac catheterization suite: does having pediatric cardiac anesthesiologists make a difference?J Neurosurg Anesthesiol. 2023;35:160-165.
29.
BlackKPolitisGFauberN, et al.Analysis of anesthesia related severe adverse events in congenital catheterization cases from a single institution. Paediatr Anaesth. 2023;33:583-587.
30.
ReichlNRablEShehuN, et al.Ambulatory sedation for children under 6 years with CHD in MRI and CT. Cardiol. Young2023;34(3):647-653. doi:10.1017/S1047951123003207
31.
BursteinDSRossiAFJacobsJP, et al.Variation in models of care delivery for children undergoing congenital heart surgery in the United States. World J Pediatr Congenit Heart Surg. 2010;1:8-14.
32.
PasqualiSKOhyeRGLuM, et al.Variation in perioperative care across centers for infants undergoing the Norwood procedure. J Thorac Cardiovasc Surg. 2012;144:915-921.
33.
PasqualiSKDimickJBOhyeRG. Time for a more unified approach to pediatric health care policy? the case of congenital heart care. JAMA. 2015;314:1689-1690.
34.
BaijalRGFakharHSintonJHuangXStaggersKMossadEB. Perioperative risk assessment in children with congenital heart disease undergoing noncardiac procedures. J Cardiothorac Vasc Anesth. 2023;37:1714-1722.
35.
WaldmanJCWhitneyGMTwiteMDIngRJ. Institutional-specific risk stratification of children with congenital heart disease undergoing noncardiac procedures. J Cardiothorac Vasc Anesth. 2023;37:1723-1725.
36.
HiraiNSaitoJNakaiKNoguchiSHashibaEHirotaK. Association between regional oxygen saturation and central venous saturation in pediatric patients undergoing cardiac surgery: a prospective observational study. Paediatr Anaesth. 2023;33:913-922.
37.
IliopoulosICooperDSReagorJA, et al.Absolute versus relative near-infrared spectroscopy in pediatric cardiac patients. Crit Care Med. 2023;24:204-212.
38.
KurthCDLevyWJMcCannJ. Near-infrared spectroscopy cerebral oxygen saturation thresholds for hypoxia–ischemia in piglets. J Cerebr Blood Flow Metabol. 2002;22:335-341.
39.
KöditzHDroucheADennhardtNSchmidtMSchultzMSchultzB. Depth of anesthesia, temperature, and postoperative delirium in children and adolescents undergoing cardiac surgery. BMC Anesthesiol. 2023;23:148.
40.
ChenHSoetiknoAXuSSureshSWalterJR. Advanced wireless monitoring for children in the cardiac perioperative setting. Paediatr Anaesth. 2023;33:670-672.
41.
FragassoTRaggiVPassaroDTardellaLLasinioGJRicciZ. Predicting acute kidney injury with an artificial intelligence-driven model in a pediatric cardiac intensive care unit. Crit Care. 2023;3:37.
42.
HoffmanTMWernovskyGAtzAM, et al.Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease. Circulation. 2003;107:996-1002.
43.
BurkhardtBERückerGStillerB. Prophylactic milrinone for the prevention of low cardiac output syndrome and mortality in children undergoing surgery for congenital heart disease. Cochrane Database Syst Rev2015;(3):CD009515. doi:10.1002/14651858.CD009515.pub2
44.
SaengsinKSperottoFLuM, et al.Administration of milrinone following tetralogy of Fallot repair increases postoperative volume administration without improving cardiac output. Anesth Analg. 2023;137:1056-1065.
45.
PortmanMASleeAERothSJ, et al.Triiodothyronine supplementation in infants undergoing cardiopulmonary bypass: a randomized controlled trial. Semin Thorac Cardiovasc Surg. 2023;35:105-112.
46.
HolladayJWinchPMorseJ, et al.Acetaminophen pharmacokinetics in infants and children with congenital heart disease. Paediatr Anaesth. 2023;33:46-51.
47.
GroganKThibaultCMoorthyGProdellJNicolsonSCZuppaA. Dose escalation pharmacokinetic study of intranasal atomized dexmedetomidine in pediatric patients with congenital heart disease. Anesth Analg. 2023;136:152-162.
48.
KimEChoiBKangP, et al.Pharmacokinetics of dexmedetomidine in pediatric patients undergoing cardiac surgery with cardiopulmonary bypass. Paediatr Anaesth. 2023;33:303-311.
49.
HashiyaMOkuboYKatoT. Effects of dexmedetomidine on brain and inflammatory outcomes in pediatric cardiac surgery: a systematic review and meta-analysis of randomized controlled trials. J Cardiothorac Vasc Anesth. 2023;37:1013-1020.
50.
KaracaerFBiricikEIlgınelM, et al.The anti-inflammatory and antioxidant effects of propofol and sevoflurane in children with cyanotic congenital heart disease. J Cardiothorac Vasc Anesth. 2023;37:65-72.
