Coregulation,Dysregulation,Self-Regulation: An Integrative Analysis and Empirical Agenda for Understanding Adult Attachment,Separation,Loss,and Recovery
Restricted accessResearch articleFirst published online May, 2008
Coregulation,Dysregulation,Self-Regulation: An Integrative Analysis and Empirical Agenda for Understanding Adult Attachment,Separation,Loss,and Recovery
An integrative framework is proposed for understanding how multiple biological and psychological systems are regulated in the context of adult attachment relationships, dysregulated by separation and loss experiences, and, potentially, re-regulated through individual recovery efforts. Evidence is reviewed for a coregulatory model of normative attachment, defined as a pattern of interwoven physiology between romantic partners that results from the conditioning of biological reward systems and the emergence of felt security within adult pair bonds. The loss of coregulation can portend a state of biobehavioral dysregulation, ranging from diffuse psychophysiological arousal and disorganization to a full-blown (and highly organized) stress response. The major task for successful recovery is adopting a self-regulatory strategy that attenuates the dysregulating effects of the attachment disruption. Research evidence is reviewed across multiple levels of analysis, and the article concludes with a series of testable research questions on the interconnected nature of attachment, loss, and recovery processes.
Affleck, G., & Tennen, H. (1996). Construing benefits from adversity: Adaptational significance and dispositional underpinnings. Journal of Personality , 64, 899-922.
2.
Affleck, G., Tennen, H., Croog, S., & Levine, S. (1987). Causal attributions, perceived benefits, and morbidity after a heart attack: An eight-year study. Journal of Consulting & Clinical Psychology, 55, 29-35.
3.
Ainsworth, M.D.S. (1967). Infancy in Uganda: Infant care and the growth of attachment. Baltimore, MD: Johns Hopkins University Press.
4.
Ainsworth, M.D.S., Blehar, M.C., Waters, E., & Wall, S. (1978). Patterns of attachment: A psychological study of the Strange Situation. Hillsdale, NJ: Lawrence Erlbaum.
5.
Amato, P.R. (2000). The consequences of divorce for adults and children . Journal of Marriage & the Family, 62, 1269-1287.
6.
Aragona, B.J., Liu, Y., Yu, Y.J., Curtis, J.T., Detwiler, J.M., Insel, T.R., et al. (2006). Nucleus accumbens dopamine differentially mediates the formation and maintenance of monogamous pair bonds. Nature Neuroscience, 9, 133-139.
7.
Bartrop, H.R., Luckhurst, E., Lazarus, L., Kiloh, L.G., & Penny, R. (1977). Depressed lymphocyte function after bereavement . Lancet, 1, 834-836.
8.
Baumeister, R.F., & Leary, M.R. (1995). The need to belong: Desire for interpersonal attachments as a fundamental human motivation. Psychological Bulletin , 117, 497-529.
9.
Belluzzi, J.D., & Stein, L. (1977). Enkephalin may mediate euphoria and drive-reduction reward. Nature, 266, 556-558.
10.
Berntson, G.G., Cacioppo, J.T., Binkley, P.F., Uchino, B.N., Quigley, K.S., & Fieldstone, A. (1994). Autonomic cardiac control: III. Psychological stress and cardiac response in autonomic space as revealed by pharmacological blockades. Psychophysiology, 31, 599-608.
11.
Berntson, G.G., Cacioppo, J.T., & Quigley, K.S. (1991). Autonomic determinism: The modes of autonomic control, the doctrine of autonomic space, and the laws of autonomic constraint . Psychological Review, 98, 459-487.
12.
Black, P.H. (2002). Stress and the inflammatory response: A review of neurogenic inflammation. Brain, Behavior, and Immunity , 16, 622-635.
Boker, S.M., & Laurenceau, J.-P. (2006). Dynamical systems modeling: An application to the regulation of intimacy and disclosure in marriage. In T. A. Walls & J. L. Schafer (Eds.), Models for intensive longitudinal data (pp. 195-218). Oxford, UK: Oxford University Press.
15.
Bonanno, G.A. (2004). Loss, trauma, and human resilience: Have we underestimated the human capacity to thrive after extremely aversive events?American Psychologist, 59, 20-28.
16.
Bonanno, G.A., & Kaltman, S. (1999). Toward an integrative perspective on bereavement . Psychological Bulletin, 125, 760-776.
17.
Bonanno, G.A., Keltner, D., Holen, A., & Horowitz, M.J. (1995). When avoiding unpleasant emotions might not be such a bad thing: Verbal-autonomic response dissociation and midlife conjugal bereavement. Journal of Personality & Social Psychology, 69, 975-989.
18.
Bonanno, G.A., Wortman, C.B., Lehman, D.R., Tweed, R.G., Haring, M., Sonnega, J., et al. (2002). Resilience to loss and chronic grief: A prospective study from preloss to 18-months post-loss. Journal of Personality & Social Psychology, 83, 1150-1164.
19.
Bower, J.E., Kemeny, M.E., Taylor, S.E., & Fahey, J.L. (1998). Cognitive processing, discovery of meaning, CD4 decline, and AIDS-related mortality among bereaved HIV-seropositive men. Journal of Consulting & Clinical Psychology, 66, 979-986.
20.
Bowlby, J. (1958). The nature of the child's tie to his mother. International Journal of Psycho-Analysis, 41, 89-113.
21.
Bowlby, J. (1982). Attachment and loss: Vol 1. Attachment (2nd ed.). New York: Basic Books. (Original work published 1969)
22.
Bowlby, J. (1973). Attachment and loss: Vol 2. Separation. New York: Basic Books.
23.
Bowlby, J. (1980). Attachment and loss: Vol 3. Loss: Sadness and depression. New York: Basic Books .
24.
Bremner, J.D., & Vermetten, E. (2001). Stress and development: Behavioral and biological consequences. Development and Psychopathology, 13, 473-489.
25.
Bruijnzeel, A.W., Repetto, M., & Gold, M.S. (2004). Neurobiological mechanisms in addictive and psychiatric disorders. Psychiatric Clinics of North America, 27, 661-674.
26.
Cacioppo, J.T., Burleson, M.H., Poehlmann, K.M., Malarkey, W.B., Kiecolt-Glaser, J.K., Berntson, G.G., et al. (2000). Autonomic and neuroendocrine responses to mild psychological stressors: Effects of chronic stress on older women . Annals of Behavioral Medicine, 22, 140-148.
27.
Capps, L., & Bonanno, G.A. (2000). Narrative bereavement: Thematic and grammatical predictors of adjustment to loss. Discourse Processes, 30, 1-25.
28.
Carter, C.S. (1998). Neuroendocrine perspectives on social attachment and loss. Psychoneuroendocrinology, 23, 779-818.
29.
Carter, C.S. (2007). Sex differences in oxytocin and vasopressin: Implications for autism spectrum disorders? Behavioural Brain Research , 176, 170-186.
30.
Carter, C.S., & Altemus, M. (1997). Integrative functions of lactational hormones in social behavior and stress management. In C. S. Carter, I. I. Lederhendler, & B. Kirkpatrick (Eds.), The integrative neurobiology of affiliation (pp. 164-174). New York: New York Academy of Sciences.
Carter, C.S., Williams, J.R., Witt, D.M., & Insel, T.R. (1992). Oxytocin and social bonding. In C. A. Pederson, J. D. Caldwell , G. F. Jirikowski, & T. R. Insel (Eds.), Oxytocin in maternal, sexual, and social behaviors. Annals of the New York Academy of Sciences: Vol. 652 (pp. 204-211). New York: New York Academy of Sciences.
33.
Cassidy, J. (1999). The nature of the child's ties. In J. Cassidy & P. R. Shaver (Eds.), Handbook of attachment: Theory, research, and clinical applications (pp. 3-20). New York: Guilford Press.
34.
Chrousos, G.P., & Gold, P.W. (1992). The concepts of stress and stress system disorders: Overview of physical and behavioral homeostasis. Journal of the American Medical Association, 267, 1244-1252.
35.
Cicchetti, D., & Rogosch, F.A. (1996). Equifinality and multifinality in developmental psychopathology. Development and Psychopathology, 8, 597-600.
36.
Coan, J.A. (in press). Toward a neuroscience of attachment. In J. Cassidy & P. R. Shaver (Eds.), Handbook of attachment: Theory, research, and clinical applications (2nd ed.). New York: Guildford Publications.
37.
Coan, J.A., Schaefer, H.S., & Davidson, R.J. (2006). Lending a hand: Social regulation of the neural response to threat. Psychological Science, 17, 1032-1039.
38.
Cohen, S., & Herbert, T.B. (1996). Health psychology: Psychological factors and physical disease from the perspective of human psychoneuroimmunology. Annual Review of Psychology, 47, 113-142.
39.
Cohen, S., & Wills, T.A. (1985). Stress, social support and the buffering hypothesis . Psychological Bulletin, 98, 310-357.
40.
Cole, S.W., & Kemeny, M.E. (2001). Psychosocial influences on the progression of HIV infection. In R. Ader, D. L. Felten, & N. Cohen (Eds.), Psychoneuroimmunology: Vol. 1 (pp. 1-20). New York: Academic Press.
41.
Cole, S.W., Kemeny, M.E., & Taylor, S.E. (1997). Social identity and physical health: Accelerated HIV progression in rejection-sensitive gay men. Journal of Personality & Social Psychology, 72, 320-335.
42.
Crowell, J.A., Treboux, D., Gao, Y., Fyffe, C., Pan, H., & Waters, E. (2002). Assessing secure base behavior in adulthood: Development of a measure, links to adult attachment representations and relations to couples' communication and reports of relationships. Developmental Psychology, 38, 679-693.
43.
Dantzer, R. (2001). Cytokine-induced sickness behavior: Where do we stand? Brain, Behavior, and Immunity, 15, 7-24.
44.
Dantzer, R.,Wollman, E. E., & Yirmiya, R. (Eds.). (1999). Cytokines, stress, and depression. New York: Kluwer-Academic/Plenum .
45.
Depue, R.A., & Morrone-Strupinsky, J.V. (2005). A neurobehavioral model of affiliative bonding: Implications for conceptualizing a human trait of affiliation. Behavioral and Brain Sciences, 28, 313-395.
46.
Dhabhar, F.S., & McEwen, B.S. (1996). Stress-induced enhancement of antigen-specific cell-mediated immunity. Journal of Immunology , 156, 2608-2615.
47.
Diamond, L.M. (2001). Contributions of psychophysiology to research on adult attachment: Review and recommendations. Personality and Social Psychology Review, 5, 276-295.
48.
Diamond, L.M., & Hicks, A.M. (2004). Psychobiological perspectives on attachment: Implications for health over the lifespan. In W. S. Rholes & J. A. Simpson (Eds.), Adult attachment: Theory, research, and clinical implications (pp. 240-263). New York: Guilford.
49.
Diamond, L.M., Hicks, A.M., & Otter-Henderson, K. (in press). Every time you go away: Changes in affect, behavior, and physiology associated with travel-related separations from romantic partners. Journal of Personality and Social Psychology.
50.
Dickerson, S.S., & Kemeny, M.E. (2004). Acute stressors and cortisol responses: A theoretical integration and synthesis of laboratory research. Psychological Bulletin, 130, 355-391.
51.
Doherty, N.A., & Feeney, J.A. (2004). The composition of attachment networks throughout the adult years. Personal Relationships, 11, 469-488.
52.
Ehlers, C.L., Frank, E., & Kupfer, D.J. (1988). Social zeitgebers and biological rhythms. Archives of General Psychiatry, 45, 948-952.
53.
Emery, R.E. (1994). Renegotiating family relationships: Divorce, child custody, and mediation. New York: Guilford Press.
54.
Feldman, R. (2007). Parent-infant synchrony: Biological foundations and developmental outcomes. Current Directions in Psychological Science, 16, 340-345.
55.
Feldman, R., & Eidelman, A.I. (2007). Maternal postpartum behavior and the emergence of infant-mother and infant-father synchrony in preterm and full-term infants: The role of neonatal vagal tone. Developmental Psychobiology, 49(3), 290-302.
56.
Feldman, R., Weller, A., Zagoory-Sharon, O., & Levine, A. (2007). Evidence for a neuroendocrinological foundation of human affiliation: Plasma oxytocin levels across pregnancy and the postpartum period predict mother-infant bonding. Psychological Science , 18, 965-970.
57.
Ferrer, E., & McArdle, J.J. (2003). Alternative structural models for multivariate longitudinal data analysis. Structural Equation Modeling, 10, 493-524.
58.
Field, T. (1985). Attachment as psychobiological attunement: Being on the same wavelength. In M. Reite & T. Field (Eds.), The psychobiology of attachment and separation (pp. 415-454). Orlando, FL: Academic.
59.
Field, T. (1994). The effects of mother's physical and emotional unavailability on emotion regulation. Monographs of the Society for Research in Child Development, 59, 208-277.
60.
Folkman, S. (2001). Revised coping theory and the process of bereavement . In M. S. Stroebe, R. O. Hansson, W. Stroebe, & H. Schut (Eds.), Handbook of bereavement research: Consequences, coping, and care (pp. 563-584). Washington, DC: American Psychological Association.
61.
Fraley, R.C., Garner, J.P., & Shaver, P.R. (2000). Adult attachment and the defensive regulation of attention and memory: Examining the role of preemptive and postemptive defensive processes. Journal of Personality and Social Psychology , 79, 816-826.
62.
Fraley, R.C., & Shaver, P.R. (1999). Loss and bereavement: Attachment theory and recent controversies concerning "grief work" and the nature of detachment. In J. Cassidy & P. R. Shaver (Eds.), Handbook of attachment: Theory, research, and clinical applications (pp. 735-759). New York: Guilford Press.
63.
Futterman, A.D., Kemeny, M.E., Shapiro, D., & Fahey, J.L. (1994). Immunological and physiological changes associated with induced positive and negative mood. Psychosomatic Medicine , 56(6), 499-511.
64.
George, C., Kaplan, N., & Main, M. (1984). Adult attachment interview protocol. Unpublished manuscript, University of California- Berkley.
65.
Goodkin, K., Baldewicz, T.T., Blaney, N.T., Asthana, D., Kumar, M., Shapshak, P., et al. (2001). Physiological effects of bereavement and bereavement support group interventions. In M. S. Stroebe, O. Hansson, W. Stroebe, & H. Schut (Eds.), Handbook of bereavement research: Consequences, coping, and care (pp. 671-703). Washington, DC: American Psychological Association.
66.
Goodkin, K., Feaster, D.J., Tuttle, R.S., Blaney, N.T., Kumar, M., Baum, M.K., et al. (1996). Bereavement is associated with time-dependent decrements in cellular immune functioning in asymptomatic human immunodeficiency virus type 1-seropositive homosexual men. Clinical and Diagnostic Laboratory Immunology, 3, 109-118.
67.
Gottman, J., Swanson, C., & Swanson, K. (2002). A general systems theory of marriage: Nonlinear difference equation modeling of marital interaction. Personality and Social Psychology Review, 6, 326-340.
68.
Grewen, K.M., Girdler, S.S., Amico, J., & Light, K.C. (2005). Effects of partner support on resting oxytocin, cortisol, norepinephrine, and blood pressure before and after warm partner contact. Psychosomatic Medicine, 67, 531-538.
69.
Gross, J.J., & Levenson, R.W. (1993). Emotional suppression: Physiology, self-report, and expressive behavior. Journal of Personality and Social Psychology, 64, 970-986.
70.
Gump, B.B., Polk, D.E., Kamarck, T.W., & Shiffman, S.M. (2001). Partner interactions are associated with reduced blood pressure in the natural environment: Ambulatory monitoring evidence from a healthy, multiethnic adult sample. Psychosomatic Medicine, 63, 423-433.
71.
Hall, M., & Irwin, M. (2001). Physiological indices of functioning in bereavement . In M. S. Stroebe, R. O. Hansson, W. Stroebe, & H. Schut (Eds.), Handbook of bereavement research: Consequences, coping, and care (pp. 473-492). Washington, DC: American Psychological Association.
72.
Hazan, C., & Diamond, L.M. (2000). The place of attachment in human mating. Review of General Psychology, 4, 186-204.
73.
Hazan, C., Gur-Yaish, N., & Campa, M. (2004). What does it mean to be attached? In W. S. Rholes & J. A. Simpson (Eds.), Adult attachment: New directions and emerging issues (pp. 55-85). New York: Guilford Press.
74.
Hazan, C., & Shaver, P. (1987). Romantic love conceptualized as an attachment process. Journal of Personality & Social Psychology, 52, 511-524.
75.
Hazan, C., & Shaver, P.R. (1992). Broken attachments: Relationship loss from the perspective of attachment theory. In T. L. Orbuch (Ed.), Close relationship loss (pp. 90-110). New York: Springer-Verlag.
76.
Hazan, C., & Zeifman, D. (1994). Sex and the psychological tether. In K. Bartholomew & D. Perlman (Eds.), Attachment processes in adulthood (pp. 151-178). London: Jessica Kingsley.
77.
Hazan, C., & Zeifman, D. (1999). Pair bonds as attachments: Evaluating the evidence . In J. Cassidy & P. R. Shaver (Eds.), Handbook of attachment: Theory, research, and clinical applications (pp. 336-354). New York: Guilford Press.
78.
Heinrichs, M., Baumgartner, T., Kirschbaum, C., & Ehlert, U. (2003). Social support and oxytocin interact to suppress cortisol and subjective responses to psychosocial stress. Biological Psychiatry, 54, 1389-1398.
79.
Helgeson, V.S. (2003). Cognitive adaptation, psychological adjustment, and disease progression among angioplasty patents: 4 years later. Health Psychology, 22(1), 30-38.
80.
Hennessy, M.B., Deak, T., & Schiml-Webb, P.A. (2001). Stress-induced sickness behaviors: An alternative hypothesis for responses during maternal separation . Developmental Psychobiology, 39, 76-83.
81.
Hennessy, M.B., Schiml-Webb, P.A., Miller, E.E., Maken, D.S., Bullinger, K.L., & Deak, T. (2007). Anti-inflammatory agents attenuate the passive responses of guinea pig pups: Evidence for stress-induced sickness behavior during maternal separation. Psychoneuroendocrinology, 32, 508-515.
82.
Hetherington, E.M., & Kelly, J. (2002). For better or for worse: Divorce reconsidered . New York: Norton.
83.
Hofer, M.A. (1984). Relationships as regulators: A psychobiological perspective on bereavement. Psychosomatic Medicine, 46, 183-197.
84.
Hofer, M.A. (1987). Early social relationships: A psychobiologist's view. Child Development, 58, 633-647.
85.
Hofer, M.A. (1994). Hidden regulators in attachment, separation, and loss. Monographs of the Society for Research in Child Development , 59, 250-283.
86.
Hofer, M.A. (1995). Hidden regulators: Implications for a new understanding of attachment, separation, and loss. In S. Goldberg & R. Muir (Eds.), Attachment theory: Social, developmental, and clinical perspectives (pp. 203-230). Hillsdale, NJ: Analytic Press.
87.
Hofer, M.A. (1996). On the nature and consequences of early loss. Psychosomatic Medicine, 58, 570-581.
88.
Hofer, M.A. (2006). Psychobiological roots of early attachment. Current Directions in Psychological Science, 15, 84-88.
89.
Holt-Lunstad, J., Uchino, B.N., Smith, T.W., Olson-Cerny, C., & Nealey-Moore, J.B. (2003). Social relationships and ambulatory blood pressure: Structural and qualitative predictors of cardiovascular function during everyday social interactions. Health Psychology , 22, 388-397.
90.
House, J.S., Landis, K.R., & Umberson, D. (1988). Social relationships and health. Science, 241, 540-545.
91.
Insel, T.R. (1992). Oxytocin: A neuropeptide for affiliation: Evidence from behavioral, receptor autoradiographic, and comparative studies. Psychoneuroendocrinology, 17, 3-35.
92.
Insel, T.R. (1997). A neurobiological basis of social attachment. American Journal of Psychiatry, 154, 726-735.
93.
Insel, T.R. (2000). Toward a neurobiology of attachment. Review of General Psychology, 4, 176-185.
94.
Insel, T.R. (2003). Is social attachment an addictive disorder? Physiology & Behavior, 79, 351-357.
95.
Insel, T.R., & Hulihan, T.J. (1995). A gender-specific mechanism for pair bonding: Oxytocin and partner preference formation in monogamous voles. Behavioral Neuroscience, 109, 782-789.
96.
Insel, T.R., & Young, L.J. (2001). The neurobiology of attachment. Nature Neuroscience, 2, 129-136.
97.
Irwin, M., Daniels, M., Risch, S.C., Bloom, E.T., & Weiner, H. (1988). Plasma cortisol and natural killer cell activity during bereavement. Biological Psychiatry, 24, 173-178.
98.
Irwin, M., Daniels, M., Smith, T.L., Bloom, E.T., & Weiner, H. (1987). Impaired natural killer cell activity during bereavement . Brain, Behavior, & Immunity, 1, 98-104.
99.
Jacobs, S.C., Mason, J., Kosten, T.R., Kasl, S.V., Ostfeld, A.M., & Wahby, V. (1987). Urinary free cortisol and separation anxiety early in the course of bereavement and threatened loss. Biological Psychiatry, 22, 148-152.
Kaufman, I.C., & Rosenblum, L.A. (1967). Depression in infant monkeys separated from their mothers. Science, 155, 1030-1031.
102.
Kehoe, P., & Blass, E.M. (1986). Opioid-mediation of separation distress in 10-day-old rats: Reversal of stress with maternal stimuli. Developmental Psychobiology, 19, 385-398.
103.
Kelley, A.E., & Berridge, K.C. (2002). The neuroscience of natural rewards: Relevance to addicitve drugs. Journal of Neuroscience , 22, 3306-3311.
104.
Kemeny, M.E. (2003). The psychobiology of stress. Current Directions in Psychological Science, 12, 124-129.
105.
Kemeny, M.E., & Gruenewald, T.L. (2000). Affect, cognition, the immune system and health. In E. A. Mayer & C. Saper (Eds.), The biological basis for mind body interactions. Progress in brain research series (pp. 291-308). Amsterdam: Elsevier Science B.V.
106.
Kemeny, M.E., Weiner, H., Duran, R., Taylor, S.E., Visscher, B., & Fahey J.L. (1995). Immune system changes after the death of a partner in HIV-positive gay men. Psychosomatic Medicine, 57(6), 547-554.
107.
Kenny, D.A., Kashy, D.A., & Cook, W.L. (2006). Dyadic data analysis. New York : Guilford Press.
Kiecolt-Glaser, J.K., Kennedy, S., Malkoff, S., Fisher, L., Speicher, C.E., & Glaser, R. (1988). Marital discord and immunity in males. Psychosomatic Medicine, 50, 213-229.
110.
Kiecolt-Glaser, J.K., McGuire, L., Robles, T.F., & Glaser, R. (2002). Emotions, morbidity, and mortality: New perspectives from psychoneuroimmunology. Annual Review of Psychology, 53, 83-107.
111.
Kiecolt-Glaser, J., & Newton, T.L. (2001). Marriage and health: His and hers. Psychological Bulletin, 127, 472-503.
112.
Kirsch, P., Esslinger, C., Chen, Q., Mier, D., Lis, S., Siddhanti, S., et al. (2005). Oxytocin modulates neural circuitry for social cognition and fear in humans. Journal of Neuroscience , 25, 11489-11493.
113.
Kitson, G.C., & Holmes, W.M. (1992). Portrait of divorce: Adjustment to marital breakdown . New York: Guilford Press.
114.
Kosfeld, M., Heinrichs, M., Zak, P.J., Fischbacher, U., & Fehr, E. (2005). Oxytocin increases trust in humans. Nature, 435, 673-676.
115.
Kovacs, G.L., Sarnyai, Z., & Szabo, G. (1998). Oxytocin and addition: A review. Psychoneuroendocrinology, 23, 945-962.
116.
Kraemer, G.W. (1992). A psychobiological theory of attachment. Behavioral and Brain Sciences, 15, 493-541.
117.
Kraemer, G.W., Ebert, M.H., Schmidt, D.E., & McKinney, W.T. (1989). A longitudinal study of the effects of different rearing environments on cerebrospinal fluid norepinephrine and biogenic amine metabolites in rhesus monkeys. Neuropsychopharnacoloy , 2, 175-199.
Laurenceau, J.-P., & Bolger, N. (2005). Using diary methods to study marital and family processes. Journal of Family Psychology, 19, 86-97.
120.
Leu, S.J., & Singh, L.K. (1992). Stimulation of interleukin-6 production by corticotropin-releasing hormone. Cellular Immunology, 143, 220-227.
121.
Light, K.C., Smith, T.E., Johns, J.M., Brownley, K.A., & Hofheimer, J.A. (2000). Oxytocin responsivity in mothers of infants: A preliminary study of relationships with blood pressure during laboratory stress and normal ambulatory activity. Health Psychology, 19, 560-567.
122.
Lim, M.M., & Young, L.J. (2006). Neuropeptidergic regulation of affiliative behavior and social bonding in animals. Hormones and Behavior, 50, 506-517.
123.
Lyubomirsky, S., & Nolen-Hoeksema, S. (1993). Self-perpetuating properties of dysphoric rumination. Journal of Personality & Social Psychology, 65, 339-349.
124.
Maier, S.F., Grahn, R.E., & Watkins, L.R. (1995). 8-OH-DPAT microinjected into the region of the dorsal raphe nucleus blocks and reverses the enhancement of fear conditioning and the interference with escape produced by exposure to inescapable shock . Behavioral Neuroscience, 109, 404-413.
125.
Maier, S.F., & Watkins, L.R. (1998). Cytokines for psychologists: Implications of bidirectional immune-to-brain communication for understanding behavior, mood, and cognition . Psychological Review, 105, 83-107.
126.
Main, M. (1999). Epilogue. Attachment theory: Eighteen points with suggestions for future research. In J. Cassidy & P. R. Shaver (Eds.), Handbook of attachment: Theory, research, and clinical applications (pp. 845-888). New York: Guilford Press.
127.
Martel, F.L., Nevison, C.M., Simpson, M.J.A., & Keverne, E.B. (1995). Effects of opioid receptor blockade on the social behavior of rhesus monkeys living in large family groups. Developmental Psychobiology, 28, 71-84.
128.
Marvin, R.S., & Britner, P.A. (1999). Normative development: The ontogeny of attachment . In J. Cassidy & P. R. Shaver (Eds.), Handbook of attachment: Theory, research, and clinical applications (pp. 44-67). New York: Guilford Press.
129.
McArdle, J.J., & Hamagami, F. (2001). Latent difference score structural models for linear dynamic analyses with incomplete longitudinal data. In L. M. Collins & A. G. Sayer (Eds.), New methods for the analysis of change (pp. 139-175). Washington, DC: American Psychological Association .
130.
McCarthy, M.M. (1995). Estrogen modulation of oxytocin and its relation to behavior. In R. Ivell & J. Russell (Eds.), Oxytocin: Cellular and molecular approaches in medicine and research (pp. 235-242). New York: Plenum Press.
131.
McCubbin, J.A. (1993). Stress and endogenous opioids: Behavioral and circulatory interactions. Biological Psychology, 35, 91-122.
132.
McEwen, B.S., & Stellar, E. (1993). Stress and the individual: Mechanisms leading to disease. Archives of Internal Medicine, 153, 2093-2101.
133.
Meinlschmidt, G., & Heim, C. (2007). Sensitivity to intranasal oxytocin in adult men with early parental separation. Biological Psychiatry, 61, 1109-1111.
134.
Meyers, C.A. (1999). Mood and cognitive disorder in cancer patients receiving cytokine therapy. Advances in Experimental Medicine and Biology, 461, 75-81.
135.
Mikulincer, M., Birnbaum, G., Woddis, D., & Nachmias, O. (2000). Stress and accessibility of proximity-related thoughts: Exploring the normative and intraindividual components of attachment theory. Journal of Personality & Social Psychology, 78, 509-523.
136.
Mikulincer, M., Gillath, O., & Shaver, P.R. (2002). Activation of the attachment system in adulthood: Threat-related primes increase the accessibility of mental representations of attachment figures. Journal of Personality and Social Psychology , 83, 881-895.
137.
Mikulincer, M., & Shaver, P.R. (2003). The attachment behavioral system in adulthood: Activation, psychodynamics, and interpersonal processes. In M. P. Zanna (Ed.), Advances in experimental social psychology: Vol. 35 (pp. 53-152). San Diego: Elsevier Academic Press.
138.
Mikulincer, M., & Shaver, P.R. (2007). Attachment in adulthood: Structure, dynamics, and change. New York: Guilford Press .
139.
Mikulincer, M., & Shaver, P.R. (in press). An attachment perspective on bereavement. In M. Stroebe, H. A. Hansson , H. Schut, & W. Stroebe (Eds.), Handbook of bereavement research and practice: 21st century perspective (2nd ed.). Washington, DC: American Psychological Association.
140.
Mikulincer, M., Shaver, P.R., & Pereg, D. (2003). Attachment theory and affect regulation: The dynamics, development, and cognitive consequences of attachment-related strategies. Motivation & Emotion, 27, 77-102.
141.
Miller, G.E., Chen, E., & Zhou, E.S. (2007). If it goes up, must it come down? Chronic stress and the hypothalamic-pituitary-adrenocortical axis in humans. Psychological Bulletin, 133, 25-45.
142.
Miller, G.E., Cohen, S., & Ritchey, A.K. (2002). Chronic psychological stress and the regulation of pre-inflammatory cytokines: A glucocorticoid-resistance model. Health Psychology, 21, 531-541.
143.
Munck, A., & Guyre, P.M. (1991). Glucocorticoids and immune function. In R. Ader, D. L. Felten , & N. Cohen (Eds.), Psychoneuroimmunology (pp. 447-474). San Diego, CA: Academic Press.
144.
Murray, S.L., Holmes, J.G., & Collins, N.L. (2006). Optimizing assurance: The risk regulation system in relationships. Psychological Bulletin, 132, 641-666.
145.
Neimeyer, R.A. (2000). Searching for the meaning of meaning: Grief therapy and the process of reconstruction. Death Studies, 24, 541-558.
146.
Nelson, E., & Panksepp, J. (1998). Brain substrate of infant-mother attachment: Contributions of opioids, oxytocin, and norepinephrine. Neuroscience and Biobehavioral Reviews, 22, 437-452.
147.
Newsom, J.T. (2002). A multilevel structural equation model for dyadic data. Structural Equation Modeling, 9, 431-447.
148.
Nissen, E., Gustavsson, P., Widstrom, A.M., & Uvnäs-Moberg, K. (1998). Oxytocin, prolatin and cortisol levels in response to nursing in women after Sectio Caesarea and vaginal delivery: Relationship with changes in personality post partum. Journal of Psychosomatic Obstetrics and Gynaecology, 19, 49-58.
149.
Nolen-Hoeksema, S. (2001). Ruminative coping and adjustment to bereavement . In M. S. Stroebe, R. O. Hansson, W. Stroebe, & H. Schut (Eds.), Handbook of bereavement research: Consequences, coping, and care (pp. 545-562). Washington, DC: American Psychological Association.
150.
Nolen-Hoeksema, S., McBride, A., & Larson, J. (1997). Rumination and psychological distress among bereaved partners. Journal of Personality & Social Psychology, 72, 855-862.
151.
Nolen-Hoeksema, S., Parker, L.E., & Larson, J. (1994). Ruminative coping with depressed mood following loss. Journal of Personality & Social Psychology, 67, 92-104.
152.
Panksepp, J., Nelson, E., & Bekkedal, M. (1997). Brain systems for the mediation of social separation-distress and social-reward: Evolutionary antecedents and neuropeptide intermediaries . In C. S. Carter & I. I. Lederhendler (Eds.), The integrative neurobiology of affiliation. Annals of the New York Academy of Sciences: Vol. 807 (pp. 78-100). New York: New York Academy of Sciences.
153.
Panksepp, J., Siviy, S.M., & Normansell, L.A. (1985). Brain opioids and social emotions. In M. Reite & T. Field (Eds.), The psychobiology of attachment and separation (pp. 3-39). Orlando, FL: Academic Press.
154.
Parkes, C.M. (1998). Bereavement: Studies of grief in adult life (3rd ed.). Madison, CT: International Universities Press.
155.
Parkes, C.M. (2001). A historical overview of the scientific study of bereavement. In M. S. Stroebe, R. O. Hansson, W. Stroebe , & H. Schut (Eds.), Handbook of bereavement research: Consequences, coping, and care. (pp. 25-45). Washington, DC: American Psychological Association .
156.
Parkes, C.M., & Weiss, R.S. (1983). Recovery from bereavement. New York: Basic Books.
157.
Pedersen, C.A. (1997). Oxytocin control of maternal behavior: Regulation by sex steroids and offspring stimuli. In C. S. Carter, I. I. Lederhendler, & B. Kirkpatrick (Eds.), The integrative neurobiology of affiliation. Annals of The New York Academy of Sciences: Vol. 807 (pp. 126-145). New York: New York Academy of Sciences.
158.
Pennebaker, J.W., Mayne, T.J., & Francis, M.E. (1997). Linguistic predictors of adaptive bereavement . Journal of Personality and Social Psychology, 72, 863-871.
159.
Pennebaker, J.W., & Seagal, J.D. (1999). Forming a story: The health benefits of narrative . Journal of Clinical Psychology, 55, 1243-1254.
160.
Pham, L.B., Taylor, S.E., & Seeman, T.E. (2001). Effects of environmental predictability and personal mastery on self-regulatory and physiological processes. Personality & Social Psychology Bulletin, 27, 611-620.
161.
Pietromonaco, P.R., Barrett, L.F., & Powers, S.I. (2006). Adult attachment theory and affective reactivity and regulation. In D. K. Snyder, J. Simpson, & J. N. Hughes (Eds.), Emotion regulation in couples and families: Pathways to dysfunction and health (pp. 57-74). Washington, DC : American Psychological Association.
162.
Polan, H.J., & Hofer, M.A. (1999). Psychobiological origins of infant attachment and separation responses. In J. Cassidy & P. R. Shaver (Eds.), Handbook of attachment: Theory, research, and clinical applications (pp. 162-180). New York: Guilford Press.
163.
Porges, S.W. (1998). Love: An emergent property of the mammalian autonomic nervous system. Psychoneuroendocrinology, 23, 837-861.
164.
Powell, L.H., Lovallo, W.R., Matthews, K.A., Meyer, P., Midgley, A.R., Baum, A., et al. (2002). Physiologic markers of chronic stress in premenopausal, middle-aged women. Psychosomatic Medicine, 64(3), 502-509.
165.
Reed, G.M., Kemeny, M.E., Taylor, S.E., & Visscher, B.R. (1999). Negative HIV-specific expectancies and AIDS-related bereavement as predictors of symptom onset in asymptomatic HIV-positive gay men. Health Psychology, 18, 354-363.
166.
Reis, H.T., Collins, W.A., & Berscheid, E. (2000). The relationship context of human behavior and development. Psychological Bulletin, 126, 844-872.
167.
Reite, M., & Boccia, M.L. (1994). Physiological aspects of adult attachment. In M. B. Sperling & W. H. Berman (Eds.), Attachment in adults (pp. 98-127). New York: Guilford Press.
168.
Reite, M., & Capitanio, J.P. (1985). On the nature of social separation and attachment. In M. Reite & T. Field (Eds.), The psychobiology of attachment and separation (pp. 415-454). Orlando, FL: Academic.
169.
Robinson-Whelen, S., Kim, C., MacCallum, R.C., & Kiecolt-Glaser, J.K. (1997). Distinguishing optimism from pessimism in older adults: Is it more important to be optimistic or not to be pessimistic? Journal of Personality & Social Psychology , 73, 1345-1353.
170.
Sander, L., Stechler, G., Burns, P., & Julia, H. (1970). Early mother- infant interaction and 24-hour patterns of activity and sleep. Journal of the American Academy of Child Psychiatry, 9, 103-123.
171.
Sapolsky, R.M., Rivier, C., Yamamoto, G., Plotsky, P., & Vale, W. (1987). Interleukin-1 stimulates the secretion of hypothalamic corticotropin releasing hormone. Science, 238, 522-544.
Seay, B., Hansen, E., & Harlow, H.F. (1962). Mother-infant separation in monkeys. Journal of Child Psychology and Psychiatry, 3, 123-132.
174.
Seay, B., & Harlow, H.F. (1965). Maternal separation in the rhesus monkey. Journal of Nervous & Mental Disorders, 140, 434-441.
175.
Segerstrom, S.C., Taylor, S.E., Kemeny, M.E., Reed, G.M., & Visscher, B.R. (1996). Causal attributions predict rate of immune decline in HIV-seropositive gay men. Health Psychology, 15, 485-493.
176.
Selye, H. (1956). The stress of life. New York : McGraw-Hill.
177.
Sgoutas-Emch, S.A., Cacioppo, J.T., Uchino, B.N., Malarkey, W., Pearl, D., Kiecolt-Glaser, J.K., et al. (1994). The effects of an acute psychological stressor on cardiovascular, endocrine, and cellular immune response: A prospective study of individuals high and low in heart rate reactivity. Psychophysiology, 31, 264-271.
178.
Shaver, P.R., & Mikulincer, M. (2002). Attachment-related psychodynamics . Attachment & Human Development, 4, 133-161.
179.
Shaver, P.R., & Tancredy, C.M. (2001). Emotion, attachment, and bereavement: A conceptual commentary. In M. Stroebe, R. O. Hannson, W. Stroebe, & H. Schut (Eds.), Handbook of bereavement research (pp. 63-88). Washington, DC: American Psychological Association.
180.
Shear, K., & Shair, H. (2005). Attachment, loss, and complicated grief. Developmental Psychobiology, 47, 253-267.
181.
Sieber, W.J., Rodin, J., Larson, L., Ortega, S., Cummings, N., Levy, S., et al. (1992). Modulation of human natural killer cell activity by exposure to uncontrollable stress. Brain, Behavior, & Immunity, 6, 141-156.
182.
Simpson, J.A., & Rholes, W.S. (1998). Attachment in adulthood. In J. A. Simpson & W. S. Rholes (Eds.), Attachment theory and close relationships (pp. 3-24). New York: Guilford Press.
183.
Simpson, J.A., Rholes, W.S., & Nelligan, J.S. (1992). Support-seeking and support-giving within couples members in an anxiety-provoking situation: The role of attachment styles. Journal of Personality and Social Psychology, 62, 434-446.
184.
Sroufe, L.A., & Waters, E. (1977). Attachment as an organizational construct. Child Development, 48, 1184-1199.
185.
Stack, S., & Eshleman, R. (1998). Marital status and happiness: A 17-nation study . Journal of Marriage & the Family, 60, 527-536.
186.
Stein, N., Folkman, S., Trabasso, T., & Richards, T.A. (1997). Appraisal and goal processes as predictors of psychological well-being in bereaved caregivers. Journal of Personality and Social Psychology, 72, 872-884.
187.
Stratakis, A., & Chrousos, G.P. (1995). Neuroendocrine and pathophysiology of the stress system. In G. P. Chrousos, R. McCarty, K. Pacak , G. Cizza, E. Sternberg, P. W. Gold, & R. Kvetnansky (Eds.), Annals of the New York Academy of Sciences: Vol. 771 (pp. 1-18). New York: New York Academy of Sciences.
188.
Stroebe, M., & Schut, H. (1999). The dual process model of coping: Rationale and description. Death Studies, 23, 197-224.
189.
Stroebe, M., Schut, H., & Stroebe, W. (2005). Attachment in coping with bereavement: A theoretical integration. Review of General Psychology, 9, 48-66.
190.
Stroebe, M., Stroebe, W., Schut, H., Zech, E., & Bout, J. (2002). Does disclosure of emotions facilitate recovery from bereavement? Evidence from two prospective studies. Journal of Consulting & Clinical Psychology, 70, 169-178.
191.
Suomi, S.J. (1999). The emotional dynamics of disruptions in attachment relationships: Implications for theory, research, and clinical intervention . In J. Cassidy & P. R. Shaver (Eds.), Handbook of attachment: Theory, research, and clinical applications (pp. 21-43). New York: Guilford Press.
192.
Suomi, S.J., Eisele, C.D., Grady, S.A., & Harlow, H.F. (1975). Depressive behavior in adult monkeys following separation from family environment. Journal of Abnormal Psychology , 84, 576-578.
193.
Taylor, S.E. (1983). Adjustment to threatening events: A theory of cognitive adaptation. American Psychologist, 38, 1161-1173.
194.
Taylor, S.E. (2006). Tend and befriend: Biobehavioral bases of affiliation under stress. Current Directions in Psychological Science , 15, 273-277.
195.
Taylor, S.E., & Brown, J.D. (1994). "Illusion" of mental health does not explain positive illusions. American Psychologist, 49, 972-973.
196.
Taylor, S.E., Kemeny, M.E., Aspinwall, L.G., Schneider, S.G., Rodriguez, R., & Herbert, M. (1992). Optimism, coping, psychological distress, and high-risk sexual behavior among men at risk for Acquired Immunodeficiency Syndrome (AIDS). Journal of Personality & Social Psychology , 63, 460-473.
Taylor, S.E., Klein, L.C., Lewis, B.P., Gruenewald, T.L., Gurung, R.A.R., & Updegraff, J.A. (2000). Biobehavioral responses to stress in females: Tend-and-befriend, not fight-or-flight. Psychological Review, 107, 411-429.
199.
Thompson, S.C., Cheek, P.R., & Grahma, M.A. (1988). The other side of perceived control: Disadvantages and negative effects. In S. Spacapan & S. Oshkamp (Eds.), The social psychology of health (pp. 69-93). Newbury Park, CA: Sage.
200.
Toates, F. (1995). Stress: Conceptual and biological aspects. New York: John Wiley.
201.
Trinke, S.J., & Bartholomew, K. (1997). Hierarchies of attachment relationships in young adulthood. Journal of Social and Personal Relationships, 14, 603-625.
202.
Uchino, B.N. (2004). Social support and physical health: Understanding the health consequences of relationships. New Haven, CT : Yale University Press.
203.
Uchino, B.N., Cacioppo, J.T., & Kiecolt-Glaser, J.K. (1996). The relationship between social support and physiological processes: A review with emphasis on underlying mechanisms and implications for health. Psychological Bulletin , 119, 488-531.
204.
Uchino, B.N., Kiecolt-Glaser, J.K., & Glaser, R. (2000). Psychological modulation of cellular immunity . In J. T. Cacioppo, L. G. Tassinary, & G. G. Berntson (Eds.), Handbook of psychophysiology (2nd ed., pp. 397-424). New York: Cambridge University Press.
205.
Uchino, B.N., Smith, T.W., Holt-Lunstad, J.L., Campo, M., & Reblin, M. (2007). Stress and illness. In J. Cacioppo, L. Tassinary, & G. Berntson (Eds.), Handbook of psychophysiology (3rd ed., pp. 78-100). New York: Cambridge University Press.
206.
Uvnäs-Moberg, K. (1997). Physiological and endocrine effects of social contact. In C. S. Carter & I. I. Lederhendler (Eds.), The integrative neurobiology of affiliation. Annals of The New York Academy of Sciences: Vol. 807 (pp. 146-163). New York: New York Academy of Sciences.
207.
Uvnäs-Moberg, K. (1998). Oxytocin may mediate the benefits of positive social interaction and emotions. Psychoneuroendocrinology , 23, 819-835.
208.
Vormbrock, J.K. (1993). Attachment theory as applied to wartime and job-related marital separation. Psychological Bulletin, 114, 122-144.
209.
Weinfield, N.S., Sroufe, L.A., Egeland, B., & Carlson, E.A. (1999). The nature of individual differences in infant-caregiver attachment. In J. Cassidy & P. R. Shaver (Eds.), Handbook of attachment: Theory, research, and clinical applications (pp. 68-88). New York: Guilford Press.
210.
Weiss, R.S. (1975). Marital separation. New York : Basic Books.
211.
Weiss, R.S. (2001). Grief, bonds, and relationships. In M. Stroebe, R. O. Hannson , W. Stroebe, & H. Schut (Eds.), Handbook of bereavement research: Consequences, coping, and care (pp. 47-62). Washington, DC : American Psychological Association.
212.
Wortman, C.B., & Silver, R.C. (1989). The myths of coping with loss. Journal of Consulting and Clinical Psychology, 57, 349-357.
213.
Wortman, C.B., & Silver, R.C. (2001). The myths of coping with loss revisited. In M. S. Stroebe, R. O. Hansson, W. Stroebe, and H. Schut (Eds.), Handbook of bereavement research. Consequences, coping, and care (pp. 405-430). Washington, DC: American Psychological Association.
214.
Young, L.J., & Wang, Z. (2004). The neurobiology of pair bonding. Nature Neuroscience, 10, 1048-1054.
215.
Zeifman, D., & Hazan, C. (1997). A process model of adult attachment formation . In S. Duck (Ed.), Handbook of personal relationships (pp. 179-195). Chichester , UK: Wiley.
