Developments in high throughput screening (HTS) have led to new needs in automation to enable better handling of applications such as homogeneous assays and cherry picking. Software and hardware integration approaches for screening automation have been changing in concert with these new application needs. The result of this combination has been the production of robotic systems for drug discovery with improved stability and functionality. This review critically assesses some Zymark, Tecan, and Beckman solutions for current HTS requirements.
References
1.
Hamilton, S.D., Armstrong, J.W., Gerren, R.A., Janssen, A.M., Peterson, J.V. and Stanton, R.A. (1996). An overview of automated biotechnology screening. Lab. Robot. Auto.8:287-294.
2.
M. Banks, A. Binnie & S. Fogarty. (1997). High throughput screening using fully integrated robotic screening. J. Biomol. Screen.2(3): 133-135.
3.
Schumate, C., Beckey, S., Coassin, P. and Stylli, H. (1997). Ultra-High Throughput Screening. LAN2(4):24-29.
4.
Rose, D. and Lenmo, T. (1997). Challenges in implementing high-density formats for high throughput screening. LAN2(4):12-18.
5.
Alderman, E. and Elands, J. (1998). A novel approach to ultra-high throughput screening. Gen. Engin. News18(2):14-15.
