Screening of Compound Libraries... Consommé or Gumbo?

Devlin, J.J. , Liang, A. , Trinh, L. , Polokoff, M.A. , Senator, D. , Zheng, W. , Kondracki, J. , Kretschmer, P.J. , Morser, J. , Lipson, S.E. , Spann, R. , Loughlin, J.A. , Dunn, K.V. , Morrissey, M.M. (1996). High capacity screening of pooled compounds: Identification of the active compound without re-assay of pool members. Drug Dev. Res. 37:80-85.

Devos, R. , Plaetinck, G. , Cheroutre, H. , Simons, G. , Degrave, W. , Tavernier, J. , Remaut, E. , Fiers W. (1983). Molecular cloning of human interleukin 2 cDNA and its expression in E. coli. Nucleic Acids Res. 11:4307-4323.

Pirrung, M.C. , Chen, J. (1995). Preparation and screening against acetylcholinesterase of a non-peptide "indexed" combinatorial library. J. Am. Chem. Soc. 117:1240-1245.

Smith, P.W. , Lai, J.Y.Q. , Whittington, A.R. , Cox, B. , Houston, J.G. (1994). Synthesis and biological evaluation of a library containing potentially 1600 amides/esters. A strategy for rapid compound generation and screening. Biomed. Chem. Lett. 4:2821-2824.

Déprez, B. , Williard, X. , Bourel, L. , Coste, H. , Hyafil, F. , Tartar, A. (1995). Orthogonal combinatorial chemical libraries. J. Am. Chem. Soc. 117:5405-5406.