Objective: To compare the long-term self-esteem and social function outcomes of individuals with untreated and treated ADHD across childhood, adolescence, and adulthood. Method: A systematic search of 12 databases was performed to identify peer-reviewed, primary research articles, published January 1980 to December 2011, reporting long-term self-esteem and/or social function outcomes (≥2 years; life consequences distinct from symptoms) of individuals with untreated or treated ADHD. Results: Overall, 127 studies reported 150 outcomes. Most outcomes were poorer in individuals with untreated ADHD versus non-ADHD controls (57% [13/23] for self-esteem; 73% [52/71] for social function). A beneficial response to treatment (pharmacological, nonpharmacological, and multimodal treatments) was reported for the majority of self-esteem (89% [8/9]) and social function (77% [17/22]) outcomes. Conclusion: Untreated ADHD was associated with poorer long-term self-esteem and social function outcomes compared with non-ADHD controls. Treatment for ADHD was associated with improvement in outcomes; however, further long-term outcome studies are needed.
AdvokatC.LaneS. M.LuoC. (2011). College students with and without ADHD: Comparison of self-report of medication usage, study habits, and academic achievement. Journal of Attention Disorders, 15, 656-666.
2.
American Psychiatric Association. (1980). Diagnostic and statistical manual of mental disorders (3rd ed.). Washington, DC: Author.
3.
American Psychiatric Association. (1987). Diagnostic and statistical manual of mental disorders (3rd ed., rev.). Washington, DC: Author.
4.
American Psychiatric Association. (1994). Diagnostic and statistical manual of mental disorders (4th ed.). Washington, DC: Author.
5.
American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders, (4th ed., text rev.). Washington, DC: Author.
6.
AshersonP.AkehurstR.KooijJ. J.HussM.BeusterienK.SasaneR.HodgkinsP. (2012). Under diagnosis of adult ADHD: Cultural influences and societal burden. Journal of Attention Disorders, 16(Suppl. 5), 20S-38S.
7.
BiedermanJ.MickE.FaraoneS. V. (2000). Age-dependent decline of symptoms of attention deficit hyperactivity disorder: Impact of remission definition and symptom type. American Journal of Psychiatry, 157, 816-818.
8.
BiedermanJ.PettyC. R.WoodworthK. Y.LomedicoA.HyderL. L.FaraoneS. V. (2012). Adult outcome of attention-deficit/hyperactivity disorder: A controlled 16-year follow-up study. Journal of Clinical Psychiatry, 73, 941-950.
9.
BrodM.PohlmanB.LasserR.HodgkinsP. (2012). Comparison of the burden of illness for adults with ADHD across seven countries: A qualitative study. Health and Quality of Life Outcomes, 10, 47.
CanuW. H.CarlsonC. L. (2007). Rejection sensitivity and social outcomes of young adult men with ADHD. Journal of Attention Disorders, 10, 261-275.
12.
CoghillD. (2010). The impact of medications on quality of life in attention-deficit hyperactivity disorder: A systematic review. CNS Drugs, 24, 843-866.
13.
CoghillD.DanckaertsM.Sonuga-BarkeE.SergeantJ. (2009). Practitioner review: Quality of life in child mental health—Conceptual challenges and practical choices. Journal of Child Psychology and Psychiatry, 50, 544-561.
14.
CohenJ. (1988). Statistical Power Analysis for the Behavioural Sciences. Hillsdale, NJ: Lawrence Erlbaum Associates.
15.
DanckaertsM.Sonuga-BarkeE. J.BanaschewskiT.BuitelaarJ.DopfnerM.HollisC.CoghillD. (2010). The quality of life of children with attention deficit/hyperactivity disorder: A systematic review. European Child & Adolescent Psychiatry, 19, 83-105.
16.
DuPaulG. J.McGoeyK. E.EckertT. L.VanBrakleJ. (2001). Preschool children with attention-deficit/hyperactivity disorder: Impairments in behavioral, social, and school functioning. Journal of the American Academy of Child & Adolescent Psychiatry, 40, 508-515.
17.
ErcanE. S.CoskunolH.VaranA.ToksozK. (2003). Childhood attention deficit/hyperactivity disorder and alcohol dependence: A 1-year follow-up. Alcohol and Alcoholism, 38, 352-356.
18.
FaraoneS. V.BiedermanJ.MickE. (2006). The age-dependent decline of attention deficit hyperactivity disorder: A meta-analysis of follow-up studies. Psychological Medicine, 36, 159-165.
19.
GoksoyrP. K.NottestadJ. A. (2008). The burden of untreated ADHD among adults: The role of stimulant medication. Addictive Behaviors, 33, 342-346.
20.
HinshawS. P.OwensE. B.ZaleckiC.HugginsS. P.Montenegro-NevadoA. J.SchrodekE.SwansonE. N. (2012). Prospective follow-up of girls with attention-deficit/hyperactivity disorder into early adulthood: Continuing impairment includes elevated risk for suicide attempts and self-injury. Journal of Consulting and Clinical Psychology, 80, 1041-1051.
21.
HodgkinsP.ArnoldL. E.ShawM.CaciH.KahleJ.WoodsA. G.YoungS. (2011). A systematic review of global publication trends regarding long-term outcomes of ADHD. Frontiers in Psychiatry, 2, 84.
22.
HosainG. M.BerensonA. B.TennenH.BauerL. O.WuZ. H. (2012). Attention deficit hyperactivity symptoms and risky sexual behavior in young adult women. Journal of Women’s Health, 21, 463-468.
23.
KesslerR. C.AdlerL.BarkleyR.BiedermanJ.ConnersC. K.DemlerO.ZaslavskyA. M. (2006). The prevalence and correlates of adult ADHD in the United States: Results from the National Comorbidity Survey Replication. American Journal of Psychiatry, 163, 716-723.
24.
KlassenA. F.MillerA.FineS. (2004). Health-related quality of life in children and adolescents who have a diagnosis of attention-deficit/hyperactivity disorder. Pediatrics, 114, e541-e547.
25.
MiyamotoR.KikuchiY. (2012). Gender differences of brain activity in the conflicts based on implicit self-esteem. PLoS ONE, 7, e37901.
26.
MrugS.MolinaB. S.HozaB.GerdesA. C.HinshawS. P.HechtmanL.ArnoldL. E. (2012). Peer rejection and friendships in children with attention-deficit/hyperactivity disorder: Contributions to long-term outcomes. Journal of Abnormal Child Psychology, 40, 1013-1026.
27.
MTA Cooperative Group. (2004). National Institute of Mental Health Multimodal Treatment Study of ADHD follow-up: 24-month outcomes of treatment strategies for attention-deficit/hyperactivity disorder. Pediatrics, 113, 754-761.
28.
National Institute for Health and Clinical Excellence. (2009). Attention deficit hyperactivity disorder: Diagnosis and management of ADHD in children, young people and adults. Retrieved from http://www.nice.org.uk/nicemedia/live/12061/42060/42060.pdf.
29.
NewarkP. E.StieglitzR. D. (2010). Therapy-relevant factors in adult ADHD from a cognitive behavioural perspective. Attention Deficit and Hyperactivity Disorders, 2, 59-72.
30.
NuttD. J.FoneK.AshersonP.BrambleD.HillP.MatthewsK.YoungS. (2007). Evidence-based guidelines for management of attention-deficit/hyperactivity disorder in adolescents in transition to adult services and in adults: Recommendations from the British Association for Psychopharmacology. Journal of Psychopharmacology, 21, 10-41.
31.
PolanczykG.de LimaM. S.HortaB. L.BiedermanJ.RohdeL. A. (2007). The worldwide prevalence of ADHD: A systematic review and metaregression analysis. American Journal of Psychiatry, 164, 942-948.
32.
RasmussenK.LevanderS. (2009). Untreated ADHD in adults: Are there sex differences in symptoms, comorbidity, and impairment?Journal of Attention Disorders, 12, 353-360.
33.
SciberrasE.OhanJ.AndersonV. (2012). Bullying and peer victimisation in adolescent girls with attention-deficit/hyperactivity disorder. Child Psychiatry & Human Development, 43, 254-270.
34.
Scottish Intercollegiate Guidelines Network. (2009). Management of attention deficit and hyperkinetic disorders in children and young people: A national clinical guideline. Edinburgh, Scotland. Retrieved from http://www.sign.ac.uk/pdf/sign112.pdf
35.
SibleyM. H.EvansS. W.SerpellZ. N. (2010). Social cognition and interpersonal impairment in young adolescents with ADHD. Journal of Psychopathology and Behavioral Assessment, 32, 193-202.
36.
United Nations Statistics Division. (2012, August). Composition of macro geographical (continental) regions, geographical sub-regions, and selected economic and other groupings. Retrieved from http://unstats.un.org/unsd/methods/m49/m49regin.htm
37.
WillcuttE. G. (2012). The prevalence of DSM-IV attention-deficit/hyperactivity disorder: A meta-analytic review. Neurotherapeutics, 9, 490-499.
38.
WilsonJ. M.MarcotteA. C. (1996). Psychosocial adjustment and educational outcome in adolescents with a childhood diagnosis of attention deficit disorder. Journal of the American Academy of Child & Adolescent Psychiatry, 35, 579-587.
39.
World Health Organization. (1992). International classification of diseases (ICD-10). Geneva, Switzerland: Author.
WuE. Q.HodgkinsP.Ben-HamadiR.SetyawanJ.XieJ.SikiricaV.ErderM. H. (2012). Cost effectiveness of pharmacotherapies for attention-deficit hyperactivity disorder: A systematic literature review. CNS Drugs, 26, 581-600.
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