Objective: The purpose of the study is to further examine the effectiveness of computerized working memory intervention among Chinese population. Method: In comparing the performance of experimental group with those of control group, General Linear Model Analysis (repeated measures) was applied to neurological and behavioral measures obtained for working memory, response inhibition, and inattention and hyperactive symptoms. Results: For experimental group that received high-intensity training in school setting, there was a significant improvement in working memory reflected in neuropsychological measures as well as parent-rated behavioral measures as compared with the control group. Conclusion: Our results generally supported the effectiveness of group-based computerized training. It might be served as a cost-effective intervention in semistructured settings, with high-intensity training and minimal therapist involvement.
AaltoS.BrückA.LaineM.NågrenK.RinneJ. O. (2005). Frontal and temporal dopamine release during working memory and attention tasks in healthy humans: A positron emission tomography study using the high-affinity dopamine D2 receptor ligand [11C]FLB 457. Journal of Neuroscience, 25, 2471-2477.
2.
AllowayT. P.GathercoleS. E.KirkwoodH.ElliottJ. (2009). The cognitive and behavioral characteristics of children with low working memory. Child Development, 80, 606-621.
3.
BäckmanL.NybergL.SoveriA.JohanssonJ.AnderssonM.DahlinE.RinneJ. O. (2011). Effects of working-memory training on striatal dopamine release. Science, 333, 718.
4.
BaddeleyA. D. (1992). Working memory. Science, 255, 556-559.
5.
BaddeleyA. D. (2000). The episodic buffer: A new component of working memory?Trends in Cognitive Sciences, 4, 417-423.
6.
BaddeleyA. D. (2003). Working memory: Looking back and looking forward. Nature Reviews Neuroscience, 4, 829-839.
7.
BaddeleyA. D. (2007). Working memory, thought, and action. New York, NY: Oxford University Press.
8.
BaddeleyA. D.HitchG. J. (1974). Working memory. In BowerG. A. (Ed.), Recent advances in learning and motivation (pp. 47-89). New York, NY: Academic Press.
9.
BrozoskiT. J.BrownR. M.RosvoldH. E.GoldmanP. S. (1979). Cognitive deficit caused by regional depletion of dopamine in prefrontal cortex of rhesus monkey. Science, 205, 929-932.
10.
CainK.OakhillJ.LemmonK. (2004). Individual differences in the inference of word meanings from context: The influence of reading comprehension, vocabulary knowledge, and memory capacity. Journal of Educational Psychology, 96, 671-681.
11.
CaseyB. J.TrainorR. J.OrendiJ. L.SchubertA. B.NystromL. N.GieddJ. N.RapoportJ. L. (1997). A developmental functional MRI study of prefrontal activation during performance of a go-no-go task. Journal of Cognitive Neuroscience, 9, 835-847.
12.
CohenJ. (1988). Statistical power analysis for the behavioral sciences (2nd ed.). Mahwah, NJ: Lawrence Erlbaum.
13.
CorbettaM.ShulmanG. L. (2002). Control of goal-directed and stimulus-driven attention in the brain. Nature Reviews Neuroscience, 3, 201-215.
14.
CurtisC. E.D’EspositoM. (2003). Persistent activity in the prefrontal cortex during working memory. Trends in Cognitive Sciences, 7, 415-423.
15.
EdinF.KlingbergT.JohanssonP.McNabF.TegnerJ.CompteA. (2009). Mechanism for top-down control of working memory capacity. Proceedings of the National Academy of Sciences of the United States of America, 106, 6802-6807.
16.
EdinF.MacoveanuJ.OlesenP.TegnerJ.KlingbergT. (2007). Stronger synaptic connectivity as a mechanism behind development of working memory-related brain activity during childhood. Journal of Cognitive Neuroscience, 19, 750-760.
17.
EngelP. M. J.SantosF. H.GathercoleS. E. (2008). Are working memory measures free of socio-economic influence?Journal of Speech, Language, and Hearing Research, 51, 1580-1587.
18.
FletcherP. C.HensonR. N. (2001). Frontal lobes and human memory: Insights from functional neuroimaging. Brain, 124, 849-881.
19.
GaravanH.RossT. J.SteinE. A. (1999). Right hemispheric dominance of inhibitory control: An event-related functional MRI study. Proceedings of the National Academy of Sciences of the United States of America, 96, 8301-8306.
20.
GathercoleS. E.PickeringS. J.KnightC.StegmannZ. (2004). Working memory skills and educational attainment: Evidence from national curriculum assessments at 7 and 14 years of age. Applied Cognitive Psychology, 18, 1-16.
HeY.ChanR. W. S. (2009). Computerized working memory training for children with ADHD: A pilot study in Hong Kong. Hong Kong Journal of Mental Health, 35, 18-30.
23.
HitchG. J.TowseJ. N.HuttonU. (2001). What limits children’s working memory span? Theoretical accounts and applications for scholastic development. Journal of Experimental Psychology: General, 130, 184-198.
24.
HolmesJ.GathercoleS. E.DunningD. L. (2009). Adaptive training leads to sustained enhancement of poor working memory in children. Developmental Science, 12, F9-F15. doi:10.111/j.1467-7687.200900848.x
25.
HolmesJ.GathercoleS. E.PlaceM.DunningD. L.HiltonK.ElliottJ. G. (2010). Working memory deficits can be overcome: Impacts of training and medication on working memory in children with ADHD. Applied Cognitive Psychology, 24, 827-836.
26.
Hong Kong Government, Education Department & Hong Kong Psychological Corporation. (1981). Hong Kong Wechsler Intelligence Scale for Children Manual. New York: Author.
27.
KarbachJ.KrayJ. (2009). How useful is executive control training? Age differences in near and far transfer of task-switching training. Developmental Science, 12, 978-990.
28.
KlingbergT.FernellE.OlesenP. J.JohnsonM.GustafssonP.DahlströmK.WesterbergH. (2005). Computerized training of working memory in children with ADHD: A randomized, controlled trial. Journal of the American Academy of Child & Adolescent Psychiatry, 44, 177-186.
29.
KlingbergT.ForssbergH.WesterbergH. (2002). Training of working memory in children with ADHD. Journal of Clinical and Experimental Neuropsychology, 24, 781-791.
30.
KremenW. S.JacobsenK. C.XianH.EisenS. A.EavesL. J.TsuangM. T.LyonsM. J. (2007). Genetics of verbal working memory process: A twin study of middle-aged men. Neuropsychology, 21, 569-580.
31.
LaiY. C.LeungW. L.LukS. L.WongS. Y.LawS. C.HoK. Y. (2011). Validation of the Chinese strengths and weaknesses of ADHD-symptoms and Normal-Behaviors Questionnaire in Hong Kong. Journal of Attention Disorders.
32.
LezakM. D. (1995). Neuropsychological assessment. New York, NY: Oxford University Press.
33.
LidowM. S.WilliamsG. V.Goldman-RakicP. S. (1998). The cerebral cortex: A case for a common site of action of antipsychotics. Trends in Pharmacological Sciences, 19, 136-140.
34.
LindenD. E. (2007). The working memory networks of the human brain. Neuroscientist, 13, 257-267.
35.
MartinussenR.HaydenJ.Hogg-JohnsonS.TannockR. (2005). A meta-analysis of working memory impairments in children with attention-deficit/hyperactivity disorder. Journal of American Academy of Child & Adolescent Psychiatry, 44, 377-384.
36.
McNabF.KlingbergT. (2008). Prefrontal cortex and basal ganglia control access to working memory. Nature Neuroscience, 11, 103-107.
37.
McNabF.VarroneA.FardeL.JucaiteA.BystritskyP.ForssbergH.KlingbergT. (2009). Changes in cortical dopamine D1 receptor binding associated with cognitive training. Science, 323, 800-802.
38.
MezzacappaE.BucknerJ. C. (2010). Working memory training for children with attention problems or hyperactivity: A school-based pilot study. School Mental Health, 2, 202-208. doi:10.1007/s12310-010-9030-9
39.
MillerG. A. (1956). The magical number seven, plus-or-minus two or some limits on our capacity for processing information. Psychological Review, 63, 81-97.
40.
MiyakeA.FriedmanN. P.EmersonM. J.WitzkiA. H.HowerterA.WagerT. D. (2000). The unity and diversity of executive functions and their contributions to complex “frontal lobe” tasks: A latent variable analysis. Cognitive Psychology, 41, 49-100.
41.
MüllerU.von CramonD. Y.PollmannS. (1998). D1- versus D2-receptor modulation of visuospatial working memory in humans. Journal of Neuroscience, 18, 2720-2728.
42.
OlesenP. J.WesterbergH.KlingbergT. (2004). Increased prefrontal and parietal activity after training of working memory. Nature Neuroscience, 7, 75-79.
43.
RainerG.MillerE. K. (2000). Effects of visual experience on the representation of objects in the prefrontal cortex. Neuron, 27, 179-189.
44.
RapportM. D.AldersonR. M.KoflerM. J.SarverD. E.BoldenJ.SimsV. (2008). Working memory deficits in boys with attention deficit/hyperactivity disorder (ADHD): The contribution of the central executive and subsystem processes. Journal of Abnormal Child Psychology, 36, 825-837.
45.
RapportM. D.BoldenJ.KoflerM.SarverD.RaikerJ.AldersonR. (2009). Hyperactivity in boys with attention-deficit/hyperactivity disorder (ADHD): A ubiquitous core symptom or manifestation of working memory deficits?Journal of Abnormal Child Psychology, 37, 521-534.
46.
Raven, J. C., Court, J. H., & Raven, J. (2000). Manual for Raven’s Progressive Matrices and Vocabulary Scales. Research Supplement No. 3 (2nd/3rd edition): A compendium of international and North American normative and validity studies together with a review of the use of the RPM in neuropsychological assessment. Oxford, UK: Oxford Psychologists Press.
47.
RuedaM. R.RothbartM. K.McCandlissB. D.PosnerP. (2005). Training, maturation, and genetic influences on the development of executive attention. Proceedings of the National Academy of Sciences of the United States of America, 102, 14931-14936.
48.
SwansonJ. M.SchuckS.MannM.CarlsonC.HartmanK.SergeantJ. A.McClearyR. (2001). Categorical and dimensional definitions and evaluations of symptoms of ADHD: The SNAP and SWAN rating scales. Available from http://www.adhd.net
49.
TakeuchiH.SekiguchiA.TakiY.YokoyamaS.YomogidaY.KomuroN.KawashimaR. (2010). Training of working memory impacts structural connectivity. Journal of Neuroscience, 30, 3297-3303.
50.
ThorellL. B.LindqvistS.NutleyS. B.BohlinG.KlingbergT. (2009). Training and transfer effects of executive functions in preschool children. Developmental Science, 12, 106-113.
51.
VijayraghavanS.WangM.BirnbaumS. G.WilliamsG. V.ArnstenA. F. T. (2007). Inverted-U dopamine D1 receptor actions on prefrontal neurons engaged in working memory. Nature Neuroscience, 10, 376-384.
52.
WechslerD. (1981). WAIS-R manual. New York, NY: The Psychological Corporation.
53.
WesterbergH.JacobaeusH.HirvikoskiT.ClevbergerP.OstenssonM. L.BartfaiA.KlingbergT. (2007). Computerized working memory training after stroke: A pilot study. Brain Injury, 21, 21-29.
54.
WesterbergH.KlingbergT. (2007). Changes in cortical activity after training of working memory: A single-subject analysis. Physiology & Behavior, 92, 186-192.
55.
WillcuttE. G.DoyleA. E.NiggJ. T.FaraoneS. V.PenningtonB. F. (2005). Validity of the executive function theory of attention-deficit/hyperactivity disorder: A meta-analytic review. Biological Psychiatry, 57, 1336-1346.
