Objective: To develop and evaluate a questionnaire, the ADHD Impact Module for Adults (AIM-A), to dimension quality of life for adults with attention-deficit/hyperactivity disorder (ADHD). Method: Six multi-item AIM scales were developed and evaluated in 317 participants enrolled in an open-label trial. Multitrait scaling analysis and correlations between the AIM-A and the ADHD Rating Scale were evaluated. Differences in scale scores based on severity (clinician rated), subtype, previous medication experience, and sensitivity to change were examined, and F statistics were compared for the AIM-A and the ADHD Rating Scale. Results: 100-80% scaling successes were observed for the AIM-A scales. Alpha coefficients were ≥.83. Significant correlations were observed (range: .494 to .200). The AIM-A discriminated based on severity, subtype, and medication experience (p ≤ .01) and was sensitive to change (n = 23, p ≤ .001). Conclusion: Psychometric findings are encouraging. Future efforts will examine validity and responsiveness in larger clinical samples with different therapeutic interventions. (J. of Att. Dis. 2007; 11(3) 351—362