SakamotoKM, MignaccaRC, GassonJC.Signal transduction by granulocyte-macrophage colony-stimulating factor and interleukin-3 receptors. Receptors Channels1994;2:175–81.
2.
SakamotoKM, GassonJC.Clinical applications of human granulocyte-macrophage colony-stimulating factor. International Journal of Cell Cloning1991;9:531–41.
3.
SakamotoKM, GoldeDW, GassonJC.The biology and clinical applications of granulocyte-macrophage colony-stimulating factor. J Pediatr1991;118:S17–20.
4.
GassonJC.The molecular physiology of GM-CSF. Blood1991;77:1131–45.
5.
BradleyTR, MetcalfD.The growth of mouse bone marrow cells in vitro. Australian Journal of Experimental Biology and Medical Science1966;44:287–300.
6.
GassonJC, WeisbartRH, KaufmanSE, ClarkSC, HewickRM, WongGG, GoldeDW.Purified human granulocyte-macrophage colony-stimulating factor: direct action on neutrophils. Science1984;226:1339–42.
7.
DiPersioJ, BillingP, KaufmanS, EghtesadyP, WilliamsRE, GassonJC.Characterization of the human granulocyte-macrophage colony-stimulating factor receptor. J Biol Chem1988;264:1834–41.
8.
HuebnerK, IsobeM, CroceCM, GoldeDW, KaufmanSE, GassonJC.The human gene encoding GM-CSF is at 5q21-32, the chro-mosome region deleted in the 5q- anomaly. Science1985;230:1282–5.
9.
BrandtSJ, PetersWP, AtwaterSK, KurtzbergJ, BorowitzMJ, JonesRB, ShpallEJ, BastRC, GilbertCJ, OetteDH.Effect of recombi-nant human granulocyte-macrophage colony-stimulating factor on hematopoietic reconstitution after high-dose chemotherapy and autolo-gous bone marrow transplantation. N Engl J Med1988;318:869–76.
10.
NemunaitisJ, SingerJW, BucknerCD, HillR, StorbR, ThomasED, ApplebaumER.Use of recombinant human granulocyte-macrophage colony-stimulating factor in autologous marrow transplan-tation for lymphoid malignancies. Blood1988;72:834–6.
11.
MertelsmannR, HerrmannF, HechtT, SchultzG.Hematopoietic growth factors in bone marrow transplantation. Bone Marrow Transplant1990;6:73–7.
12.
GroopmanJE, MitsuyasuRT, DeLeoMJ, OetteDH, GoldeDW.Effect of recombinant human granulocyte-macrophage colony-stimulat-ing factor on myelopoiesis in the acquired immunodeficiency syndrome. N Engl J Med1987;317:593–8.
13.
Vadhan-RajS, BuescherS, BroxmeyerH, LeMaistreA, Lepe-ZunigaJL, VenturaG, JehaS, HorwitzLJ, TrujilloJM, GillisS.Stimulation of myelopoiesis in patients with aplastic anemia by recombi-nant human GM-CSF. N Engl J Med1988;319:1628–34.
14.
ChamplinRE, NimerSD, IrelandP, OetteD, GoldeDW.Treatment of refractory aplastic anemia with recombinant human granu-locyte-macrophage colony-stimulating factor. Blood1989;73:694–9.
15.
Vadhan-RajS, KeatingM, LeMaistreA, HittelmanWN, McCredleK, TrujilloJM, BroxmeyerHE, HenneyC, GuttermanJU.Effect of recombinant human granulocyte-macrophage colony-stimulat-ing factor in patients with myelodysplastic syndromes. N Engl J Med1987;317:1545–52.
16.
GanserA, VolkersB, GreherJ, OttmannOG, WaltherF, BecherR, BergmannL, SchulzG, HoelzerD.Recombinant human GM-CSF in patients with myelodysplastic syndromes–a phase I/II trial. Blood1989;73:31–7.
17.
EsteyEH, KurzockR, TalpazM, McCredieKB, ObrienS, KantjarianHM, KeatingMJ, DeisserothAB, GuttermanJU.Effects of low doses of recombinant human granulocyte-macrophage colony-stim-ulating factor (GM-CSF) in patients with myelodysplastic syndromes. Br J Haematol1991;7:291–5.
18.
BazanJF.Hematopoietic receptors and helical cytokines. Immunol Today1990;11:350–4.
19.
GearingDP, KingJA, GoughNM, NicolaNA.Expression cloning of a receptor for human granulocyte-macrophage colony-stimu-lating factor. EMBO J1989;8:3667–76.
20.
HayashidaK, KitamuraT, GormanDM, AraiK, YokotaT, MiyajimaA.Molecular cloning of a second subunit of the receptor for human granulocyte-macrophage colony-stimulating factor (GM-CSF): reconstitution of a high-affinity GM-CSF receptor. Proc Natl Acad Sci USA1990;87:9655–9.
21.
TakakiS, TominagaA, HitoshiY, MitaS, SonodaE, YamaguchiN, TakatsuK.Molecular cloning and expression of the murine inter-leukin-5 receptor. EMBO J1990;9:4367–74.
22.
GoughN, GearingD, NicolaN, BakerE, PrichardM, CallenD, SutherlandG.Localization of the human GM-CSF receptor gene to the X-Y pseudo-autosomal region. Nature1990;345:734–6.
23.
SchmittR, BruynsE, SnodgrassH.Hematopoietic development of embryonic stem cells in vitro: cytokine and receptor gene expression. Genes Dev1991;5:728–40.
24.
KellerG, KennedyM, PapayanopoulouT, WilesM.Hematopoietic commitment during embryonic stem cell differentiation in culture. Mol Cell Biol1993;13:473–86.
25.
McClanahanT, DalrmpleS, BarkettM, LeeF.Hematopoietic growth factor receptor genes as markers of lineage commitment during in vitro development of hematopoietic cells. Blood1993;81:2903–15.
26.
RainesM, LiuL, QuanS, DiPersioJ, GoldeD.Identification and molecular cloning of a soluble GM-CSF receptor. Proc Natl Acad Sci USA1991;88:8203–7.
27.
DiederichsK, BooneT, KarplusPA.Novel fold and putative receptor binding site of GM-CSF. Science1991;254:1779–82.
28.
KasteleinRA, ShanafeltAB.GM-CSF receptor: interaction and activation. Oncogene1993;8:231–6.
29.
ShanafeltA, MiyajimaA, KitamuraT, KasteleinR.The amino-terminal helix of GM-CSF and IL-5 governs high affinity binding to their receptors. EMBO J1991;10:4105–12.
30.
MiyajimaA, MuiA, OgorochiT, SakamakiK.Receptors for GM-CSF, interleukin-3, and interleukin-5. Blood1993;7:1960–74.
31.
SakamakiK, MiyajimaI, KitamuraT, MiyajimaA.Critical cyto-plasmic domains of the common beta subunit of the human GM-CSF, IL-3, and IL-5 receptors for growth signal transduction and tyrosine phosphorylation. EMBO J1992;11:3541–9.
32.
TakakiS, MurataY, KitamuraT, MiyajimaA, TominagaA, TakatsuK.Reconstitution of the functional receptors for murine and human IL-5. J Exp Med1993;177:1523–9.
33.
RoncoL, SilvermanS, WongS, SlamonD, ParkL, GassonJ.Conserved amino acid in the human GM-CSF receptor-binding subunit essential for tyrosine phosphorylation and proliferation. J Biol Chem1993;269:277–83.
34.
WitthuhnB, QuelleF, SilvennoinenO, YiT, TangB, MiuraO, IhleJ.JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin. Cell1993;74:227–36.
35.
QuelleFW, SatoN, WitthuhnBA, InhornRC, EderM, MiyajimaA, GriffinJD, IhleJN.JAK2 associates with the Beta c chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region. Mol Cell Biol1994;14:4335–41.
36.
MatsuguchiT, InhornRC, CarlessoN, XuG, DrukerB, GriffinJD.Tyrosine phosphorylation of p95Vav in myeloid cells is regulated by GM-CSF, IL-3, and steel factor and is constitutively increased by p210BCR/ABL. EMBO J1995;14:257–65.
37.
SatohT, NakafukuM, MiyajimaA, KaziroY.Involvement of ras p21 protein in signal transduction pathways from IL-2, IL-3, and GM-CSF, but not from IL-4. Proc Natl Acad Sci USA1991;88:3314–8.
38.
DuronioV, WelhamM, AbrahamS, DrydenP, SchraderJ.p21ras activation via hematopoietin receptors and c-kit requires tyrosine kinase activity but not tyrosine phosphorylation of p21ras GTPase acti-vating protein. Proc Natl Acad Sci USA1992;89:1587–91.
39.
SatohT, NakafukuM, KaziroY.Function of ras as a molecular switch in signal transduction. J Biol Chem1992;267:24149–52.
40.
CutlerR, LiuL, DamenJ, CrystalG.Steel factor stimulates the ser/thr phosphorylation of the IL-3 receptor. J Biol Chem1993;268:21463–5.
41.
McCormickF.Proteins regulating ras and its relatives. Nature1993;366:643–54.
42.
van LohuizenM, VerbeekS, KrimpenfortP, DomenJ, SarisC, RadaszkiewiczT, BernsA.Predisposition to lymphomagenesis in pim-1 transgenic mice: cooperation with c-myc and N-myc in murine leukemia virus-induced tumors. Cell1989;56:673–82.
43.
KanakuraY, DrukerB, CannistraS, FurukawaY, TorimotoY, GriffinJ.Signal transduction of the human granulocyte-macrophage colony-stimulating factor and interleukin-3 receptors involves tyrosine phosphorylation of a common set of cytoplasmic proteins. Blood1990;76:706–15.
44.
VarnumB, LimRW, KujubuDA, LunerSJ, KaufmanSE, GreenbergerJS, GassonJC, HerschmanHR.Granulocyte-macrophage colony-stimulating factor and tetradecanoyl phorbol acetate induce a distinct, restricted subset of primary-response TIS genes in both prolif-erating and terminally differentiated myeloid cells. Mol Cell Biol1989;9:3580–5.
45.
SakamotoKM, FraserJK, LeeHJJ, LehmanE, GassonJC.Granulocyte-macrophage colony-stimulating factor and interleukin-3 signaling pathways converge on the CREB-binding site in the human egr-1 promoter. Mol Cell Biol1994;14:5975–85.
46.
LeeJH-J, MignaccaRC, SakamotoKM.Transcriptional activa-tion of Egr-1 by GM-CSF, but not IL-3, requires phosphorylation of CREB on serine 133. J Biol Chem1995;270:15979–83.
47.
WongA, SakamotoKM.Granulocyte-macrophage colony-stim-ulating factor induces the transcriptional activation of egr-1 through a protein kinase A-independent signaling pathway. J Biol Chem1995;270:30271–3.
48.
LarnerA, DavidM, FeldmanG, IgarashiK, HackettR, WebbD, SwitzerS, PetricoinE, FinbloomD.Tyrosine phosphorylation of DNA binding proteins by multiple cytokines. Science1993;261:1730–3.
49.
Ruff-JamisonS, ChenK, CohenS.Induction by EGF and inter-feron-gamma of tyrosine phosphorylated DNA binding proteins in mouse liver nuclei. Science1993;261:1733–6.
50.
SadowskiH, ShuaiK, DarnellJ, GilmanM.A common nuclear signal transduction pathway activated by growth factor and cytokine receptors. Science1993;261:1739–44.
51.
MuiAL, WakaoH, HaradaN, O'FarrellAM, MiyajimaA.Interleukin-3, granulocyte-macrophage colony-stimulating factor, and interleukin-5 transduce signals through two forms of STAT5. J Leukoc Biol1995;57:799–803.
