BögerRH, Bode-BögerSM, FrölichJC.The L-arginine-nitric oxide pathway. Role in atherosclerosis and therapeutic implications. Atherosclerosis1996;127:1–11.
2.
ReesDD, PalmerRMJ, MoncadaS.Role of endothelium-derived nitric oxide in the regulation of blood pressure. Proc Natl Acad Sci USA1989:86:3375–3378.
3.
FozardJR, PartML.Haemodynamic responses to No-monomethyl-L-arginine in spontaneously hypertensive and normotensive Wistar-Kyoto rats. Br J Pharmacol1991;102:823–826.
4.
HaynesWG, NoonJP, WalkerBR, WebbDJ.Inhibition of nitric oxide synthesis increases blood pressure in healthy humans. J Hypertens1993:11:1375–1380.
5.
BaylisC, MitrukaB, DengA.Chronic blockade of nitric oxide synthesis in the rat produces systemic hypertension and glomerular damage. J Clin Invest1992;90:278–281.
6.
BögerRH, Bode-BögerSM, GereckeU, FrölichJC.Long-term administration of L-arginine, L-NAME, and the exogenous NO donor molsidomine modulate urinary nitrate and cGMP excretion in rats -correlation with vascular reactivity. Cardiovasc Res1994;28:494–499.
7.
HuangPL, HuangZ, MashimoH, BlochKD, MoskowitzMA, BevanJA, FishmanMC.Hypertension in mice lacking the gene for endothelial nitric oxide synthase. Nature1995;377:239–243.
8.
LinKF, ChaoL, ChaoJ.Prolonged reduction of high blood pressure with human nitric oxide synthase gene delivery. Hypertension1997;30:307–313.
9.
PanzaJA, GarciaCE, KilcoyneCM, QuyyumiAA, CannonRO.Impaired endothelium-dependent vasodilation in patients with essential hypertension. Circulation1995;91:1732–1738.
10.
CayatteAJ, PacinoJJ, HortenK, CohenRA.Chronic inhibition of nitric oxide production accelerates neointima formation and impairs endothelial function in hypercholesterolemic rabbits. Arterioscler Thromb1994;14:753–759.
11.
BögerRH, Bode-BögerSM, Phivthong-NgamL, BöhmeM, BrandesRP, MüggeA, FrölichJC.Dietary L-arginine slows the progression of atherosclerosis in cholesterol-fed rabbits-comparison with lovastatin. Circulation1997;96:1282–1290.
12.
PickeringTG, HarshfieldGA, KleinertHD, BlankS, LaraghJH.Blood pressure during normal daily activities, sleep and exercise. J Am Med Assoc1982;247:992–996.
13.
ManciaG, FerrariA, GregoriniL, ParatiG, PomidossiG, BertinieriG, GrassiG, di RienzoM, PedottiA, ZanchettiA.Blood pressure and heart rate variabilities in normotensive and hypertensive human beings. Circ Res1983;53:96–104.
14.
ReinbergA.New aspects of human chronopharmacology. Arch Toxicol1976;36:327–339.
BögerRH, Bode-BögerSM, GereckeU, GutzkiFM, TsikasD, FrölichJC.Urinary NO3- excretion as an indicator of nitric oxide formation in vivo during oral administration of L-arginine or L-NAME in rats. Clin Exp Pharmacol Physiol1996;23:11–15.
17.
O'BrienE, MeeF, AtkinsN, O'MalleyK.Accuracy of the Takeda TM-2420, TM-2020 determined by the British Hypertension Society protocol. J Hypertens1991;9:571–572.
18.
O'BrienE, MeeF, AtkinsN, O'MalleyK.Accuracy of the Spacelabs 90207 determined by the British Hypertension Society protocol. J Hypertens1991;9:573–574.
19.
TsikasD, BögerRH, Bode-BögerSM, GutzkiFM, FrölichJC.Quantification of nitrite and nitrate in human urine and plasma as pentafluorobenzyl derivatives by gas chromatography mass spectrometry using their 15N-labeled analogs. J Chromatogr B Biomed Appl1994;661:185–191.
20.
MojónA, FernándezJR, HermidaRC.ChronoLab. An interactive software package for chronobiologic time series analysis written for the Macintosh computer. Chronobiol Int1992;9:403–412.
21.
HalbergF.Chronobiology. Annu Rev Physiol1969;31:675–725.
22.
BinghamC, ArbogastB, CornélissenG, LeeJK, HalbergF.Inferential statistical methods for estimating and comparing cosinor parameters. Chronobiologia1982;9:397–439.
23.
NafzB, JustA, StaußHM, WagnerCD, EhmkeH, KirchheimHR, PerssonPB.Blood-pressure variability is buffered by nitric oxide. J Auton Nerv Syst1996;57:181–183.
24.
CookeJP, RossitchE, AndonNA, LoscalzoJ, DzauVJ.Flow activates an endothelial potassium channel to release an endogenous nitrovasodilator. J Clin Invest1991:88:1663–1671.
25.
Bode-BögerSM, BögerRH, SchröderEP, FrölichJC.Exercise increases systemic NO production in men. J Cardiovasc Risk1994;1: 173–178.
26.
BögerRH, Bode-BögerSM, ThieleW, JunkerW, AlexanderK, FrölichJC.Biochemical evidence for impaired nitric oxide synthesis in patients with peripheral arterial occlusive disease. Circulation1997;95: 2068–2074.
27.
GreenLC, Ruiz de LuzuriagaK, WagnerDA, RandW, IstfanN, YoungVR, TannenbaumSR.Nitrate biosynthesis in man. Proc Natl Acad Sci USA1981;78:7764–7768.
28.
RhodesPM, LeoneAM, FrancisPL, StruthersAD, MoncadaS.The L-arginine nitric oxide pathway is the major source of plasma nitrite in fasted humans. Biochem Biophys Res Commun1995;209:590–596.
29.
WennmalmA, BenthinG, EdlundA, JungerstenL, Kieler-JensenN, LundinS, Nathorst WestfeltU, PeterssonAS, WaagsteinF.Metabolism and excretion of nitric oxide in humans. An experimental and clinical study. Circulation1993;73:1121–1127.
30.
JohnsonRA, FreemanRH.Sustained hypertension in the rat induced by chronic blockade of nitric oxide production. Am J Hypertens1992;5:919–922.
31.
NodeK, KitakazeM, YoshikawaH, KosakaH, HoriM.Reduced plasma concentrations of nitrogen oxide in individuals with essential hypertension. Hypertension1997;30:405–408.
32.
SierraM, GonzalezA, Gomez-AlamilloC, MonrealI, HuarteE, GilA, Sanchez-CasajusA, DiezJ.Decreased excretion of nitrate and nitrite in essential hypertensives with renal vasoconstriction. Kidney Int1998;54(suppl 68):S10–S13.
BögerRH, Bode-BögerSM, ThieleW, CreutzigA, AlexanderK, FrölichJC.Restoring vascular NO formation by L-arginine improves the symptoms of intermittent claudication in patients with peripheral arterial occlusive disease. J Am Coll Cardiol1998;32:1336–1344.
35.
BögerRH, Bode-BögerSM, SzubaA, TangphaoO, TsaoPS, ChanJR, BlaschkeTF, CookeJP.ADMA. A novel risk factor for endothelial dysfunction. Its role in hypercholesterolemia. Circulation1998;98:1842–1847.
36.
MüggeA, BrandesR, BögerRH, DwengerA, Bode-BögerSM, KienkeS, FrölichJC, LichtlenPR.Vascular release of superoxide radicals is enhanced in hypercholesterolemic rabbits. J Cardiovasc Pharmacol1994;24:994–998.
37.
BeckmanJS, YeYZ, AndersonPG, ChenJ, AccavettiMA, TarpeyMM, WhiteCR.Extensive nitration of protein tyrosines in human atherosclerosis detected by immunohistochemistry. Biol Chem Hoppe-Seyler1994;375:81–88.
38.
WilcoxJN, SubramanianRR, SundellCL, TraceyWR, PollockJS, HarrisonDG, MarsdenPA.Expression of multiple isoforms of nitric oxide synthase in normal and atherosclerotic vessels. Arterioscler Thromb Vasc Biol1997;17:2479–2488.
VincentSR, KimuraH.Histochemical mapping of nitric oxide synthase in the rat brain. Neuroscience1992;46:755–783.
41.
CabreraC, BohrD.The role of nitric oxide in the central control of blood pressure. Biochem Biophys Res Comm1995;206:77–81.
42.
AyersNA, KapasL, KruegerJM.Circadian variation of nitric oxide synthase activity and cytosolic protein levels in rat brain. Brain Res1996;707:127–130.
43.
ToflerGH, BrezinskiD, SchaferAI, CzeislerCA, RutherfordJD, WillichSN, GleasonRE, WilliamsGH, MullerJE.Concurrent morning increase in platelet aggregability and the risk of myocardial infarction and sudden cardiac death. N Engl J Med1987;316:1514–1518.
44.
FiguerasJ, LidónRM.Early morning reduction in ischemic threshold in patients with unstable angina and significant coronary disease. Circulation1995;92:1737–1742.
