Remote collection of patient-reported quality of life outcomes via text messaging in cancer patients receiving oral anti-cancer therapy

Abstract

Purpose

Patient-reported outcome measures (PROMs) are valuable tools for capturing how oral chemotherapy affects patients’ quality of life (QOL), yet their integration into routine clinical practice remains limited. This study aimed to evaluate the feasibility of using remote electronic PROMs (ePROMs) to collect QOL data from patients receiving oral anti-cancer (OAC) therapy. Specifically, we assessed patient response rates to text message prompts linking to a web-based EORTC QLQ-C30 survey and examined the practicality of incorporating text-based communication into clinical practice.

Patients and Methods

We conducted a prospective pilot study involving 64 patients (mean age 60 years; range 29–84) diagnosed with breast, colorectal, prostate, or lung cancer and actively receiving OAC therapy. Participants received automated monthly text message reminders over a 6-month period, directing them to complete the EORTC QLQ-C30 questionnaire online.

Results

The initial survey response rate was 98.4%, with monthly survey completion rates ranging from 83.6% to 96.3%. Despite overall strong engagement, some noncompliance occurred due to technical issues, forgetfulness, or early withdrawal. Across the study period, 38 significant QOL changes were identified, with a median provider notification time of 1 day (range 0–89 days). Patient satisfaction surveys revealed generally positive perceptions, with participants highlighting ease of use, convenience, and appropriate survey frequency.

Conclusion

Text message–based ePROM collection is a feasible approach for monitoring QOL in patients on OAC therapy, though completion rates vary. While patient satisfaction is high, opportunities remain to streamline the process and better integrate it into existing clinical workflows.