Stroke Prevention in Patients With Atrial Fibrillation: What Have We Learned?

Kannel WB , Abbott RD , Savage DD , McNamara PM Epidemiologic features of chronic atrial fibrillation: the Framingham study . N Engl J Med 306:1018,1982

Martin A. Atrial fibrillation in the elderly. Br Med J 1:7, 1977 (Letter)

Olsson SB Atrial fibrillation—some current problems. Acta Med Scand 207:1, 1980

Sherman DG Hart RG , Easton JD The secondary prevention of stroke in patients with atrial fibrillation. Arch Neurol 43:68. 1986

Wolf PA , DawberTR,Thomas HE Jr, Kannel WB. Epidemiologic assessment of chronic atrial fibrillation and risk of stroke: the Framingham study. Neurology 28:973, 1978

Harrison MJ , Marshall J. Atrial fibrillation, TIAs and completed strokes. Stroke 15:441, 1984

Bogousslavsky J. , Hachinski VC , Boughner DR , Fox AJ , Vinuela F. , Barnett HJ Cardiac and arterial lesions in carotid transient ischemic attacks. Arch Neurol 43:223, 1986

Koudstaal PJ , van Gijn J. , Klootwijk AP , van der Meche FG , Kappelle LJ Holter monitoring in patients with transient and focal ischemic attacks of the brain. Stroke 17: 192, 1986

Koudstaal PJ Primary and secondary prevention of stroke in patients with nonrheumatic atrial fibrillation. Eur Neurol 34:61, 1994

Petersen P. Boysen G. , Godtfredsen J. , Andersen ED , Andersen B. Placebo-controlled, randomised trial of warfarin and aspirin for prevention of thromboembolic complications in chronic atrial fibrillation. The Copenhagen AFASAK study. Lancet 1:175, 1989

Stroke Prevention in Atrial Fibrillation Study Group. Stroke Prevention in Atrial Fibrillation Study. Final results. Circulation 84:527,1991

The Boston Area Anticoagulation Trial for Atrial Fibrillation Investigators. The effect of low-dose warfarin on the risk of stroke in patients with nonrheumatic atrial fibrillation. N Engl J Med 323:1505,1990

Connolly SJ Laupacis A. , Gent M. , Roberts RS , Cairns JA , Joyner C. Canadian Atrial Fibrillation Anticoagulation (CAFA) Study. J Am Coll Cardiol 18:349,1991

Ezekowitz MD , Bridgers SL , James KE , Carliner NH , Colling CL Gornick CC, Krause-Steinraut H, Kurtzke JF, Nazarian SM, Radford MJ, Rickles FR, Shabetai R, Deykin D. Warfarin in the prevention of stroke associated with nonrheumatic atrial fibrillation. Veterans Affairs Stroke Prevention in Nonrheumatic Atrial Fibrillation Investigators . N Engl J Med 327:1406,1992

EAFT (European Atrial Fibrillation Trial) Study Group. Secondary prevention in non-rheumatic atrial fibrillation after transient ischaemic attack or minor stroke. Lancet 342:1255, 1993

Morocutti C. , Amabile G. , Fattapposta F. , Nicolosi A. , Matteoli S. , Trappolini M. Indobufen versus warfarin in the secondary prevention of major vascular events in nonrheumatic atrial fibrillation. Stroke 28:1015, 1997

International Stroke Trial Collaborative Group. The International Stroke Trial (IST): a randomized trial of aspirin, subcutaneous heparin, both, or neither among 19,435 patients with acute ischaemic stroke. Lancet 349:1569,1997

Stroke Prevention in Atrial Fibrillation II Study Investigators. Warfarin versus aspirin for prevention of thromboembolism in atrial fibrillation: Stroke Prevention in Atrial Fibrillation II study. Lancet 343:687,1994

Atrial Fibrillation Investigators. Risk factors for stroke and efficacy of antithrombotic therapy in atrial fibrillation. Analysis of pooled data from five randomized controlled trials. Arch Intern Med 54:1449, 1994

The Atrial Fibrillation Investigators. The efficacy of aspirin in patients with atrial fibrillation. Analysis of pooled data from 3 randomized trials. Arch Intern Med 157: 1237-1240, 1997

Hylek EM , Skates SJ , Sheehan MA , Singer DE An analysis of the lowest effective intensity of prophylactic anticoagulation for patients with nonrheumatic atrial fibrillation. N Engl J Med 335:540,1996

Levine M. , Hirsh J. Hemorrhagic complications of long-term anticoagulant therapy for ischemic cerebral vascular disease. Stroke 17:111,1986

Lundstrom T. , Ryden L. Haemorrhagic and thromboembolic complications in patients with atrial fibrillation on anticoagulant prophylaxis. J Intern Med 225:137, 1989

Stroke Prevention in Atrial Fibrillation Investigators. Predictors of thromboembolism in atrial fibrillation: II Echocardiographic features of patients at risk. Ann Intern Med 116:6, 1992

Hellemons Bsp , Langenberg M. , Lodder J. , Vermeer F. , Schouten Hja , van Ree JW , Knottnerus JA Primary prevention of arterial thromboembolism in patients with nonrheumatic atrial fibrillation in general practice. Cerebrovasc Dis 7(Suppl 4):11, 1997

Langenberg M. , Hellemons Bsp , Vermeer F. , Lodder J. , van Ree JW , Schouten Hja , Knottnerus JA Prevention of thromboembolism in patients with nonrheumatic atrial fibrillation. Risk of PATAF patients compared to patients of the other atrial fibrillation trials. Cerebrovasc Dis 7(Suppl 4):12, 1997

Koudstaal PJ Anticoagulant treatment in very elderly (>80 years) patients with stroke and atrial fibrillation. Cerebrovasc Dis 5:8, 1995