Lipid-Lowering Therapy in Patients with Peripheral Arterial Disease

Ebrahimi R , Saleh JR , Toggart EJ , et al . Lipid-lowering therapy in patients with peripheral arterial disease. J Cardiovasc Pharmacol Ther 9:271-277, 2004

Heart Protection Study Collaborative Group . MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: A randomised placebo-controlled trial. Lancet 360:7-22, 2002

Aronow WS , Ahn C . Frequency of new coronary events in older persons with peripheral arterial disease and serum low-density lipoprotein cholesterol > or = 125 mg/dl treated with statins versus no lipid-lowering drug. Am J Cardiol 90:789-791, 2002

Schillinger M , Exner M , Mlekusch W , et al . Statin therapy improves cardiovascular outcome of patients with peripheral artery disease. Eur Heart J 25:742-748, 2004

Mohler ER 3rd , Hiatt WR , Creager MA . Cholesterol reduction with atorvastatin improves walking distance in patients with peripheral arterial disease. Circulation 108:1481-1486, 2003

Daskalopoulou SS , Daskalopoulos ME , Liapis CD , et al . Peripheral arterial disease: A missed opportunity to administer statins so as to reduce cardiac morbidity and mortality. Curr Med Chem 12:443-452, 2005

Meade T , Zuhrie R , Cook C , et al . Bezafibrate in men with lower extremity arterial disease: Randomised controlled trial. BMJ 325:1139-1143, 2002

Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III) . JAMA 285:2486-2497, 2001

Grundy SM , Cleeman JI , Merz CN , et al ; National Heart, Lung, and Blood Institute ; American College of Cardiology Foundation ; American Heart Association . Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines. Circulation 110:227-239, 2004

Athyros VG , Papageorgiou AA , Mercouris BR , et al . Treatment with atorvastatin to the National Cholesterol Educational Program goal versus ‘usual’ care in secondary coronary heart disease prevention. The GREek Atorvastatin and Coronary-heart-disease Evaluation (GREACE) study. Curr Med Res Opin 18:220-228, 2002

Koren MJ , Hunninghake DB ; ALLIANCE Investigators . Clinical outcomes in managed-care patients with coronary heart disease treated aggressively in lipid-lowering disease management clinics: The alliance study. J Am Coll Cardiol 44:1772-1779, 2004

Cannon CP , Braunwald E , McCabe CH , et al . Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 Investigators. Intensive versus moderate lipid lowering with statins after acute coronary syndromes. N Engl J Med 350:1495-1504, 2004

Larosa JC , Grundy SM , Waters DD , et al . Intensive Lipid Lowering with Atorvastatin in Patients with Stable Coronary Disease. N Engl J Med 2005 Mar 8; [Epub ahead of print at www.nejm.org]

Hirsch AT , Duprez D . The potential role of angiotensin-converting enzyme inhibition in peripheral arterial disease. Vasc Med 8:273-278, 2003

Daskalopoulou SS , Stansby G , Mikhailidis DP . Clopidogrel and vascular disease prevention. Curr Med Res Opin 20:1835-1838, 2004

Robless P , Mikhailidis DP , Stansby G . Systematic review of antiplatelet therapy for the prevention of myocardial infarction, stroke or vascular death in patients with peripheral vascular disease. Br J Surg 88:787-800, 2001

Athyros VG , Mikhailidis DP , Papageorgiou AA , et al . For the GREACE Study Collaborative Group . Effect of Statins and Aspirin Alone and in Combination on Clinical Outcome in Dyslipidaemic Patients with Coronary Heart Disease. A subgroup analysis of the GREACE Study. Platelets 2005; in press

Athyros VG , Mikhailidis DP , Papageorgiou AA , et al . GREACE Study Collaborative Group . Effect of statins and ACE inhibitors alone and in combination on clinical outcome in patients with coronary heart disease. J Hum Hypertens 18:781-788, 2004

Athyros VG , Mikhailidis DP , Papageorgiou AA , et al . The effect of statins versus untreated dyslipidaemia on renal function in patients with coronary heart disease. A subgroup analysis of the Greek atorvastatin and coronary heart disease evaluation (GREACE) study. J Clin Pathol 57:728-734, 2004

Daskalopoulou SS , Athyros VG , Elisaf M , et al . Uric acid levels and vascular disease. Curr Med Res Opin 20:951-954, 2004

Athyros VG , Elisaf M , Papageorgiou AA , et al . GREACE Study Collaborative Group . Effect of statins versus untreated dyslipidemia on serum uric acid levels in patients with coronary heart disease: A subgroup analysis of the GREek Atorvastatin and Coronary-heart-disease Evaluation (GREACE) study. Am J Kidney Dis 43:589-599, 2004

Daskalopoulou SS , Tzovaras V , Mikhailidis DP , et al . Effect on serum uric acid levels of drugs prescribed for indications other than treating hyperuricaemia. Curr Pharm Des 2005; in press

Youssef F , Gupta P , Seifalian AM , et al . The effect of short-term treatment with simvastatin on renal function in patients with peripheral arterial disease. Angiology 55:53-62, 2004

Tsimihodimos V , Miltiadous G , Daskalopoulou SS , et al . Fenofibrate: Metabolic and pleiotropic effects. Curr Vasc Pharmacol 3:87-98, 2005

Sanguigni V , Pignatelli P , Lenti L , et al . Short-term treatment with atorvastatin reduces platelet CD40 ligand and thrombin generation in hypercholesterolemic patients. Circulation 111:412-419, 2005

Daskalopoulou SS , Mikhailidis DP , Elisaf M . Prevention and treatment of the metabolic syndrome. Angiology 55:589-612, 2004