Cell Adhesion Molecules: Implications for Neurological Disease

Muhlenhoff M. , Eckhardt M. , Bethe A. , Frosch M. , Gerardy-Schahan R. Polysialylation of NCAM by a single enzyme. Curr Biol 1966;6:1188-1191.

Rutishauser U. , Landmesser L. Polysialic acid in the vertebrate nervous system: a promoter of plasticity in cell-cell interactions. Trends Neurosci 1996;19.422-427.

Poltorak M. , Frey MA , Wnght R. , et al Increased neural cell adhesion molecule in the CSF of patients with mood disorder. J Neurochem 1966;66:1532-1538.

Poltorak M. , Khoja I. , Hemperly JJ , et al. Disturbances in cell recognition molecules (N-CAM and L1 antigen) in the CSF of patients with schizophrenia. Exp Neurol 1995;131:266-272.

Mahadik SP , Mukherjee S. , Wakade CG , Laev H. , Reddy RR , Schnur DB Decreased adhesiveness and altered cellular distribution of fibronectin in fibroblasts from schizophrenic patients. Psychiatry Res 1994;53:878-897.

Fields RD , Itoh I. Neural cell adhesion molecules in activity-dependent development and synaptic plasticity. Trends Neurosci 1996,19:473-480

Muller D. , Wang C. , Skibo G. , et al PSA-NCAM is required for activity-induced synaptic plasticity . Neuron 1996; 17:413-422.

Becker CG , Artola A. , Gerardy-Schahn R. , Becker T. , Wezl H. , Schachner M. The polysialic acid modification of the neural cell adhesion molecule is involved in spatial learning and hippocampal long-term potentiation. J Neurosci Res 1996;45. 143-152.

Barbeau D. , Liang JJ , Robitalille Y. , Quirion R. , Snvastava LK Decreased expression of the embryonic form of the neural cell adhesion molecule in schizophrenic brains. Proc Natl Acad Sci U S A 1995;92:2785-2789.

Faissner A. , Krus J. , Nieke J. , Schachner M. Expression of neural cell adhesion molecule L1 during development in neurological mutants and in the peripheral nervous system. Dev Brain Res 1984;15:69-82.

Djabali M. , Mattei MG , Roux D. , et al. The human L1 adhesion molecule is encoded by an HTF-associated gene located in Xq28. Cytogenet Cell Genet 1989;51:991.

Fransen E. , Vits L. , Van Camp G. , Willems PG The clinical spectrum of mutations in L1, a neuronal cell adhesion molecule . Am J Med Genet 1996;64:73-77.

Uyemura K. , Takeda Y. , Asou H. , Hayasaka K. Neural cell adhesion proteins and neurological diseases. J Biochem (Tokyo) 1994;116:1187-1192.

Kenwrick S. , Jouet M. , Donnai D X-linked hydrocephalus and MASA syndrome. J Med Genet 1996;33:59-65.

Fransen E. , Lemmon V. , Van Camp G. , Vits L. , Coucke P. , Willems PJ CRASH syndrome : climcal spectrum of corpus callosum hypoplasia, retardation, adducted thumbs, spastic paraparesis and hydrocephalus due to mutations in one single gene, L1. Eur J Hum Genet 1995;3:273-284

Menkes JH , Philippart M. , Clark DB Hereditary partial agenesis of corpus callosum. Arch Neurol 1964; 11: 198-208.

Kaplan P. X-linked recessive inheritance of agenesis of the corpus callosum. J Med Genet 1983;20:122-124.

Kang W-M. , Huang C-C. , Lin S-J. X-linked recessive inheritance of dysgenesis of corpus callosum in a Chinese family. Am J Med Genet 1992;44:619-623.

Jouet M. , Rosenthal A. , Armstrong G. , et al X-linked spastic paraplegia (SPG1), MASA syndrome and X-linked hydrocephalus result from mutations in the L1 gene. Nat Genet 1994;7:402-407.

Kobayashi H. , Garcia CA , Alfonso G. , Marks HG , Hoffman EP Molecular genetics of familial spastic paraplegia: a multitude of responsible genes. J Neurol Sci 1996;137:131-138.

Burton BK Recurrence risk for congenital hydrocephalus. Clin Genet 1979;16: 47-53.

Rosenthal A. , Joulet M. , Kenwnck S. Aberrant splicing of neural cell adhesion molecule L1 mRNA in a family with X-linked hydrocephalus. Nat Genet 1992;2: 107-112.

Grondona JM , Perez-Martm M. , Cifuentes M. , et al. Ependymal denudation, aqueductal obliteration and hydrocephalus after a single injection of neuraminidase into the lateral ventricle of adult rats. J Neuropathol Exp Neurol 1996;55:999-1008.

Willems PJ , Brouwer OF , Dijkstra I. , Wilmink J. X-linked hydrocephalus. Am J Med Genet 1987 ;27:921-928

Landrieu P. , Nmane J. , Ferrier G. , Lyon G. Aqueductal stenosis in X-linked hydrocephalus. a secondary phenomenon? Dev Med Child Neurol 1979;21:637-642.

Ramanathan R. , Wilkemeyer MF , Mittal B. , Pendwes G. , Charness ME Alcohol m-hibits cell-cell adhesion mediated by human L1. J Cell Biol 1996;133:381-390.

Wood PM , Schachner M. , Bunge RP Inhibition of Schwann cell myelination in vitro by antibody to the L1 adhesion molecule. J Neurosci 1990;10:3635-3645.

Lemke G. , Lamar E. , Patterson J. Isolation and analysis of the gene encoding peripheral myelin protein zero . Neuron 1988;1: 73-78.

Lmmgton C. , Webb M. , Woodhams P. A novel myelin associated glycoprotein defined by a mouse monoclonal antibody . J Neuroimmunol 1984;6:387-396.

Quarles RH Glycoprotems of myelin sheath. J Mol Neurosci 1997;81:1-12.

Uyemura K. , Kitamura K. , Miura M. Structure and molecular biology of P0 glycoprotem. In: Martenson RE , editor. Myelin: chemistry and biology. Boca Raton: CRC; 1992. p. 481-508.

Choe S. Packing of myelin protein zero. Neuron 1996 ;17:363-365

Giese KP , Martini R. , Lemke G. , Sonano P. , Schachner M. Mouse PO gene disruption leads to hypomyelinarion, abnormal expression of recognition molecules, and degeneration of myelin and axons. Cell 1992;71:565-576.

Warner LE , Hilz MJ , Appel SH , et al. Clinical phenotypes of different MPZ (PO) mutations may include Charcot-Mane Tooth type 1B, Dejenne-Sottas, and congenital hypomyelination . Neuron 1996;17:451-460.

Brunner D. , Lassmann H. , Waehneldt TV , Matthieu JM , Linington C. Differential ultrastructural localization of myelin basis protein, myelin/oligodendroglial glycoprotem, and 2',3'-cyclic nucleotide 3'phosphodiesterase in the CNS of adult rats. J Neurochem 1989;52:296-304.

Adelmann M. , Wood J. , Benzel I. , et al. The N-terminal domain of the myelin oligodendrocyte glycoprotein (MOG) induces acute demyelinating experimental autoimmune encephalomyelitis in the Lewis rat. J Neuroimmunol 1995;63:17-27.

Mendel I. , Kerlero de Rosbo N. , Ben-Nun A. A myelin ohgodendrocyte glycoprotein peptide induces typical chronic experimental autoimmune encephalomyelitis in H-2b mice: fine specificity and T cell receptor V beta expression of encephalitogemc T cells. Eur J Immunol 1995;25: 1951-1959.

Johns TG , Kerlero de Rosbo N. , et al. Myelin oligodendrocyte glycoprotein induces a demyelinating encephalomyelitis resembling multiple sclerosis. J Immunol 1995;154:5536-5541.

Bartoszewicz ZP , Noronha NB , Fujita N. , et al. Abnormal expression and glycosylation of the large and small isoforms of myelin-associated glycoprotein in dysmyelinating trembler mutants. J Neurosci Res 1995;41:27-38.

Gabriel JM , Erne B. , Miescher GC , et al Selective loss of myelin-associated glycoprotein from myelin correlates with anti-MAG antibody titer in demyelinating paraproteinaemic polyneuropathy. Brain 1996;119:775-787.

Quarles R. , Colman D. , Salzer J. , Trapp B. Myelin-associated glycoprotem: structure-function relationships and involvement in neurological diseases. In: Martenson R , editor. Myelin: biology and chemistry. Boca Raton: CRC; 1992. p. 4413-4448.

Tatum AH Experimental paraprotem neuropathy, demyelination by passive transfer of human IgM anti-myelin-associated glycoprotem. Ann Neurol 1993;33:502-506.

Probstmeier R. , Fahrig T. , Spiess E. , Schachner M. Interactions of the neural cell adhesion molecule and myelin-associated glycoprotein with collagen type I: involvement in fibnllogenesis . J Cell Biol 1992;116:1063-1070.

Mukhopadhyay G. , Doherty P. , Walsh FS , Crocker PR , Filbm MT A novel role for myelin-associated glycoprotein as an m-hibitor of axonal regeneration. Neuron 1994;13:757-767

McKerracher L. , David S. , Jackson DL , Kottis V. , Dunn RJ , Braun PE Identification of myelin-associated glycoprotein as a major myelin-derived inhibitor of neunte growth. Neuron 1994;13:805-811.

Li M. , Shibeta A. , Li C. , et al. Myelin-associated glycoprotem inhibits neunte/ axon growth and causes growth cone collapse. J Neurosci Res 1996;46:404-414.

Bartsch U. Myelination and axonal regeneration in the central nervous system of mice deficient in myelin-associated glycoprotem. J Neurocytol 1996;25:303-313.

Riehl R. , Johnson K. , Bradley R. , et al. Cadhenn function is required for axon outgrowth in retinal ganglion cells in vivo. Neuron 1996;17:837-848.

Cifuentes-Diaz C. , Nicolet M. , Goudou D. , Rieger F. , Mege RM N-cadherin expression in developing adult and denervatmg chicken neuromuscular system: accumulations at both the neuromuscular junction and the node of Ranvier. Development 1994;120:1-11.

Beesley PW , Mummery R. , Tibaldi J. N-cadherin is a major glycoprotem component of isolated rat forebram postsynaptic densities. J Neurochem 1995;64:2288-2294.

Yamagata M. , Herman JP , Sanes JR Lamina-specific expression of adhesion molecules in developing chick optic tectum. J Neurosci 1995;15:4556-4571.

Uchida N. , Honjo Y. , Johnson KR , Wheelock JM , Takeichi M. The catenin/ cadhenn adhesion system is localized in synaptic junctions bordering transmitter release zones. J Cell Biol 1996 ,135:767-779.

Fannon AM , Colman DR A model for central synaptic junctional complex formation based on the differential adhesive specificities of cadhenns. Neuron 1996; 17:423-434.

DeSilva U. , D'Arcangelo G. , Braden VV , et al. The human reelin gene: isolation, sequencing and mapping on chromosome 7 Genome Res 1997;2:157-164.

D'Arcangelo G. , Miao GG , Chen SC , Soares HD , Morgan JI , Curran T. A protem related to extracellular matrix protems deleted in the mouse mutant reeler. Nature 1995;374:719-723.

Rose LM , Richards TL , Peterson J. , Petersen R. , Alvord EC Jr. Resolution of CNS lesions following treatment of experimental allergic encephalomyelitis in macaques with monoclonal antibody to the CD18 leukocyte integrin. Mult Scler 1997;2:259-266.

Kent SJ , Karlik SJ , Cannon C. , et al. A monoclonal antibody to alpha 4 integrin suppresses and reverses active experimental allergic encephalomyelitis. J Neuroimmunol 1995;58:1-10.

Matsumota A. , Enomoto T. , Fujiwara Y. , Baba H. , Matsumoto R Enhanced aggregation of beta-amyloid-containing peptides by extracellular matrix and their degradation by the 68 kDa senne protease prepared from human brain. Neurosci Lett 1996;220:159-162.

Storey E. , Spurck T. , Pickett-Heaps J. , Beyreuther K. , Masters CL The amyloid precursor protein of Alzheimer's disease is found on the surface of static but not activity motile portions of neurites. Brain Res 1996;735:59-66.

Yamazaki T. , Koo EH , Selkoe DJ Cell surface amyloid beta-protem precursor colocalizes with beta 1 integnns at substrate contact sites in neural cells . J Neurosci 1997;17:1004-1010

Muir D. , Johnson J. , Rojiani M. , Inglis BA , Rojiani A. , Mana BL Assesment of lammm-mediated glioma invasion in vitro and by glioma tumors engrafted with rat spinal cord. J Neurooncol 1996;30:199-211.

Soussi-Yanicostas H. , Hardelin JP , Arroyo-Jimenez MM , et al. Initial charactenzation of anosmin-1, a putative extracellular matrix protein synthesized by definite neuronal cell populations in the central nervous system. J Cell Sci 1996;109.1749-1757.

Sullivan PB Hirschprung's disease. Arch Dis Child 1996;74:5-7

Matsumura K. , Yamada H. , Saito F. , Sunada Y. , Shimizu T. Peripheral nerve involvement in merosin-deficient congenital muscular dystrophy and dy mouse. Neuromuscul Disord 1997;7:7-12.

Martin PT , Kaufinan SJ , Kramer RH , Sanes JR Synaptic integnns in developing, adult, and mutant muscle: selective association of alpha 1, alpha 7A, and alpha 7B integnns with the neuromuscular junction . Dev Biol 1996;174:125-139.

Einheber S. , Schnapp LM , Salzer JL , Cappiello ZB , Milner TA Regional and ultrastructural distribution of the alpha 8 integnn subunit in developing and adult rat brain suggests a role in synaptic function. J Comp Neurol 1996;370:105-134.

Bahr BA , Staubli U. , Xiao P. , et al. Arg-Gly-Asp-Ser-selective adhesion and the stabilization of long-term potentiation: pharmacological studies and the characterization of a candidate matrix receptor J Neurosci 1997 ;17:1320-1329.

Devaux B. , Enderlin F. , Wallner B. , Smilek DE Induction of EAE in mice with recombinant human MOG, and treatment of EAE with MOG peptide. J Neuroimmunol 1997;75:169-173.

Bregman BS , Kunkel-Bagden E. , Schnell L. , Dia HN , Gao D. , Schwab ME Recovery from spinal cord injury mediated by antibody to neunte growth inhibitors . Nature 1995;378:498-501.

Kobayashi S. , Miura M. , Asou H. , Inoue HK , Ohye C. , Uyemura K. Grafts of genetically modified fibroblasts expressing neural cell adhesion molecule L1 into transected spinal cord of adult rats. Neurosci Lett 1995;188:191-194.