A 39-year-old woman with restriction of movement and macrodactyly of the great toes was found to have severe juxta-articular multiple osteophytosis of the lower limbs. The pathogenesis of this unusual condition is unknown. It may be a variant of diffuse idiopathic skeletal hyperostosis.
. O'BrienW.M.La DuB.N.BunimJ.J.: Biochemical pathological and clinical aspects of alcaptonuria, ochronosis and ochronotic arthropathy. Review of the world literature (1584–1962). Am.J. Med., 34:813–838, 1963
3.
. ResnickD.NiwayamaG.: Diffuse idiopathic skeletal hyperostosis. InDiagnosis of Bone and Joint Disease, Philadelphia, Saunders, 1989, pp. 440–451
